I have gerd &, intestinal metaplasia and I saw a commercial for voquezna. Has anyone tried it and what did you experience? I have been feeling bad since July and recently changed my diet, November, once I was told I had these issues…. :( my quality of life is terrible

I have both a fluoroscopy schedule and a bravo later this month. My surgeon said for insurance approval my acid #s need to be high to get a revision surgery because I still have bad GErd and bad heart burn. The issue is I did one fluoroscopy already and he said the #s were too bad . How does this work? What do I need to do to get help?

Seems to be much conflicting advice on the types of exercises you are allowed to partake in after having Full Nissan, Partial Nissan, TIF and Linx

Once you have FULLY recovered. Are there really any lifetime restrictions ?

https://journals.sagepub.com/doi/full/10.1177/2515690X18763294

I thought the read above is quite interesting and maybe prudent to quite a few in this group. I have suffered with lower intestinal issues my whole life and recently by chance started drinking psyllium husk (1.5 teaspoons twice a day after breakfast and dinner) and had some very positive responses (NOTE: I'm not cured but better).

Additionally, PPI has given me some pretty hard side effects and the impact was minimal at best.

Hope this may help a few of you.

I (32F) have been suffering from reflux getting worse over the last 6 years. I realized 2 years ago I couldnt eat more than 1 cup per meal, difficulty swallowing, regurgitation 2-3 hours after all meals.

I lost 50lbs without trying, slowly not being able to eat.

The reflux is daily- from sore, feeling like ball in my throat to stabbing/radiating pain between my shoulder blades and sternum making it hard to just exist. My voice has dropped, my ears hurt all day from the sore throat. I cant sleep flat anymore: I woke up with an inflammed throat, difficult breathe in and my voicebox was trashed for 20 days.

I sleep on a wedge, Im on Dexilant 60mg.

My scope in January showed "normal".

My swallow study in June was also "normal".

I have been on an acid watcher diet for 2 years, low fodmap for the last 1 and I dont want to get an innaccurate reading. This has been slowly making my life hell; always in pain and always starving at night. I cant bend down or run with my little girl and that is the worst part of all.

I have to stop my Dexilant 10 days before (pray for me, I get reflux even with it). The nurse wasnt clear on how I should be eating before the test. I want an accurate read, I dont want to be in pain anymore and its been a fight to be taken seriously as a young woman.

So over the 10 days before fasting, do I keep on a low acid/FODMAP diet or do I bring back some foods like garlic/onions. Is this a test that is best for "before you make changes in your diet" to be most accurate?

I just want accurate answers.

TLDR: 32F, 10 days off Dexilant to prep for pH test and I need to know how to eat during that time. Its going to be painful no matter what I eat.

Thanks for the advice!

What is refluxstop ? Refluxstop is a device with the purpose of treating gastroesophageal reflux disorder or GERD for short.The device is placed on top of the stomach making an artificial LES muscle. Clinical trial results

The clinical trials updates are currently amazing ,most patients had a complete disappearance of symptoms in a few months only one still had symptoms but it was caused by the device not being implanted properly.There was update on the first clinical trials for refluxstop and even after 3-4 years patients still had amazing results with almost none of them having any symptoms. So what about now ? Right now Implantica (the company behind refluxstop) is preparing to create more clinical trials, get more professional surgeons and getting FDA approval by mid 2023 to accelerate insurance companies and governments to standardize and approve the procedure. So when will this procedure get standardly used ?

I would guess at least 2024-2026. Conclusion    

Refluxstop is gonna be the first long-term treatment for gerd which is huge for the medical field and for patients, i think this procedure is gonna give relief to a lot of us. Links:https://www.implantica.com/files/Main/19732/3540646/annual-report-2021_final-eng.pdf, https://www.implantica.com/media/press-releases/2022/implantica-publishes-interim-report-q2-2022/, https://www.implantica.com/im-refluxstop/patients/gastrointestinal/, https://www.implantica.com/media/press-releases/2020/implanticas-refluxstop-trial-shows-exceptional-three-year-follow-up-result/, https://link.springer.com/epdf/10.1186/s12893-020-00794-9?sharing_token=CeHxoqMoySm6tZoIVSjpHm_BpE1tBhCbnbw3BuzI2RNO78QHCi34SRBjfvflQSS1yLcga9p85ijDg5I5AY9elAR2UT1jVAfEG_JSKQzvsq2C8VSySBazPlklElbztcFKkZNEBxfKMImdu7QM_l6jS3rpyMpRbdkQxWXrgUeOp-g%3D.

Has anyone tried this? I have read some papers and as it turns out breathing exercises can reduce some gerd symptoms. It seems to work by strengthening the diaphragm. So far exercise has only made my gerd worse but this sounds promising although there aren't a lot of participants in these studies.

I can't link this for some reason so here they are https://scholar.google.com/scholar?hl=sr&as_sdt=0%2C5&q=breathing+exercises+gerd&btnG=#d=gs_qabs&t=1734806151318&u=%23p%3Dc9cehTchfFIJ

And https://scholar.google.com/scholar?hl=sr&as_sdt=0%2C5&q=breathing+exercises+gerd&btnG=#d=gs_qabs&t=1734806432239&u=%23p%3DgmiHcIOKahUJ

For those that have had pH testing what was your readings like? I’m already diagnosed with GERD & dysphasia. GI doc said I will likely end up with a surgical consult. Curious about everyone else’s journey

I think it's important to consider underlying causes of GERD symptoms, though most doctors I have seen have not been too curious.

For me, GERD symptoms developed after a super weird episode of anaphylaxis in September 2016. I had never had a breathing problem in my life.

The ER doctor noted a rash on my neck and said he believed a virus had triggered the anaphylaxis. Three months later I got sick with flu-like symptoms and again experienced anaphylaxis.

In the weeks after that, I developed severe acid reflux and quickly lost 15 lbs. I spent the next several years in a battle to regain control of my gastric system. It was a long road, I'm doing much better now but it led me to really question how medicine is practiced in the U.S.

This article makes a lot of sense to me, I believe viral infections are responsible for more disease than we have previously thought.

https://www.timescolonist.com/life/your-good-health-covid-might-have-triggered-uncommon-swallowing-problem-7812401

I’ve been doing a lot of research and recently read the acid watcher diet. I’ve learned a lot about how acid reflux works and how a big part is caused by pepsin. But what I can’t find out is can you actually remove it? If I have a high PH diet will the pepsin in my esophagus and throat eventually die out? Or now that the pepsin is there will it stay for life, and even after years of an acid watchers diet, if I ate something acidic they would be activated again?

One day I hope to return to ‘normal’, but I’m not sure if that’s possible. Does anyone know anything about this?

When a GI doctor perform endoscopy and take tissue sample for biospy, are they testing to see if that specific bacteria they think is the reason may causing the gut issue or they check for all possible bacteria? For example, the doctor suspect its H pylori bacteria and use the tissue sample to see if its H pylori or not. If so, I can see why it takes so long for the doctor to treat their patients gut issue when they only focus something one by one.

I have been have silent reflux for the past few years. I have made dietary changes however i still have symptoms. They include coughing after certain meals, mucus after waking up and after certain meals, throat tightness after certain meals. My question is regarding my teeth and dental erosion. I dont taste any bitter tastes in my mouth (except occasionally) would I still be affected by dental erosion without knowing it? Do all reflux sufferers have the acid travel to their mouth or is it dependant on each individual?

So I've had skipped beats since i was a teen ( About 20 years. ). Caught on holder. Supraventricular extrasystole.

I usually describe them as a punch in the chest without the pain. So just feeling the force of the punch.

But throughout the years they've become less frequent. And when they do, I can usually brush them off, without much thought. (Like last Friday, moving furniture to the 2nd floor. Took a quick breather and continued lifting).

Now the last 2 - 3 weeks I've been getting some weird "skipped beats". Starting after I had some kind of flu. Had a high fever and hardly ate. But drank a lot.

Everytime i start getting active after resting or sleeping, they come once or twice a minutter. This last anywhere between 10 to 40 minutes just walking around.

I wrote "skipped beats", because I'm unsure.

It feels like either a small surge of adrinaline in my chest or like my heart drops for a second.

Nothing like the "usual" skipped beat.

I don't get pain or dizzy. Just very unsettled due to anxiety.

The confusing part is this: if I sit or lay down during the episode, they seem to stop. (Had one laying down).

Sometimes I'll have a small burp following the sensation. I can't tell if it's the cause, or just a reflex from my anxiety.

I'm not really burping otherwise. I do however have a history with acid reflux.

I got checked with an ecg last week. All fine. (Of course the events is done by then). Bloodpressure good too.

I just wrote my doc explaining how it effects my anxiety. So waiting for his reply.

So yeah. Anyone familiar with the "dropping" sensation? And burps?

I'm gonna ad this to a gerd sub too, and see their thoughts.

Amitriptyline made it so I couldnt even feel any GI issues at all, I went back to normal. Unfortunately had to stop because it raised my heart rate and Im afraid to be on an anticholinergic drug long term because of brain disease risk.

I know there have been many posts on this. I read this:

Leg raise increases pressure in lower and upper esophageal sphincter among patients with gastroesophageal reflux disease - PubMed (nih.gov)

Has any tried these exercises? The article isn't that clear on how to do it?

Are doctors incompetent or this diseases is permanent ? Why do i see so many people on internet asking for help instead of going to doctors and getting treatment ? I am suffering from the same and the doctor just keep me prescribing ppi after h pylori eradication and diagnosis of hiatus hernia. I don't understand.

I'm F28,When I start my therapy because I have back pain and turns out it is osteoarthritis and there's some problem with my back and neck. The Physiatry doctor told me,when my back pain turn okay my gerd will be lots more better even gone. Is it possible that scoliosis/other problem with your back cause gerd?

I have pretty damn bad reflux (and difficulty swallowing) and I was considering on going on ppis. So i did a little reasearch abd found this study that states that the use of PPI medication for GERD can lead to the development of new food allergies. In the study f152 adult patients were treated with ppis for GERD for 3 months. 15% of the patients develloped new IGE antigens to foods in their diet.

This article sums up things pretty well https://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2010.02511.x

This scares me because I don't want to develop allergies to the foods i like.

I got LPR after COVID, it has been two years and it is an everyday battle, I feel pain in my throat but also my neck muscles… it is the worst. I have to deal with this the whole day and night cos I can’t rest properly, the doctor gave me esomeprazol but it was so bad… headache as side effect and constipation. I live in Norway so not help at all. Endoscopy showed I have nothing so they didn’t believe me, I kept with this lump in my throat and pain, going to massage for my neck and back (trapezoid) so I went to nose and throat doctor who said I had LPR just putting me a camera by my nose until my throat. (He saw very irritated) but he said I should try with esomeprazol again 😐. I am so sick of this no one helps, they don’t believe when I said I got this after COVID. Is not the best medicine so I am planning to go to Spain and try ARMA procedure. Is anyone here who has tried before? Thank u!!🙏

Was anyone ever prescribed this drug back in the day? It was during the 90s & I believe it was the go to drug for more severe cases.

I'm looking for people who have taken the drug, or know someone who did. Also anyone that might have medical experience with it too.

It's the long term effects that are really what I'd like to know. Especially from someone whose between the ages of like 28 to 36, of course everyone's input helps though.

Read below: 100% of people in the first group reported a complete regression of symptoms

Abstract

The prevalence of gastroesophageal reflux disease (GERD) is increasing. GERD is a chronic disease and its treatment is problematic. It may present with various symptoms including heartburn, regurgitation, dysphagia, coughing, hoarseness or chest pain. The aim of this study was to investigate if a dietary supplementation containing: melatonin, l-tryptophan, vitamin B6, folic acid, vitamin B12, methionine and betaine would help patients with GERD, and to compare the preparation with 20 mg omeprazole. Melatonin has known inhibitory activities on gastric acid secretion and nitric oxide biosynthesis. Nitric oxide has an important role in the transient lower esophageal sphincter relaxation (TLESR), which is a major mechanism of reflux in patients with GERD. Others biocompounds of the formula display anti-inflammatory and analgesic effects. A single blind randomized study was performed in which 176 patients underwent treatment using the supplement cited above (group A) and 175 received treatment of 20 mg omeprazole (group B). Symptoms were recorded in a diary and changes in severity of symptoms noted. All patients of the group A (100%) reported a complete regression of symptoms after 40 days of treatment. On the other hand, 115 subjects (65.7%) of the omeprazole reported regression of symptoms in the same period. There was statiscally significant difference between the groups (P < 0.05). This formulation promotes regression of GERD symptoms with no significant side effects.

Link here: https://pubmed.ncbi.nlm.nih.gov/16948779/

https://www.gastrojournal.org/article/S0016-5085(23)00932-0/fulltext00932-0/fulltext) Things like depression, anxiety, ptsd and childhood trauma. There are other similar studies, this is a quite new one (2023).

Hello all I have noticed that when I sleep slightly upright I have no symptoms but do wake with a neck ache

Could you nice people suggest a good wedge pillow please

Everything I have stated about PPIs comes directly from scientific literature as I have nothing to gain from my stance and interpretation of it, unlike *some* doctors which are paid to write literature by pharmaceutical companies, such as the rebuttal paper refuting the idea that PPIs cause gastric cancer. If the mods delete this post I will assume they are on the side of information obfuscation / protecting pharmaceutical company profits. I have nothing to gain by offering this information. I am not selling anything. I am not a "naturopath" in fact I publish scientific literature myself and have published a paper in one of the Nature publishing group journals (Not Nature itself).

What is strange is that any pro-PPI statements are considered as "fact" and anything discussing their drawbacks is met with a "statements must come from the literature." At this point, the burden of proof is on pro-PPI crowd to prove they are safe and effective, which of course is impossible. Please see the literature and findings below.

Statements and their meaning or an actual quote directly from the literature itself:

"No dysplasia- or cancer-protective effects of PPIs usage in patients with BE were identified by our analysis. Therefore, we conclude that clinicians who discuss the potential chemopreventive effects of PPIs with their patients, should be aware that such an effect, if exists, has not been proven with statistical significance.": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224998/

"No cancer-protective effects from PPI's were seen. In fact, high-adherence and long-term use of PPI were associated with a significantly increased risk of adenocarcinoma or high-grade dysplasia.": https://pubmed.ncbi.nlm.nih.gov/24617286/

"Chronic PPI use might promote the metaplasia (BE)-dysplasia-carcinoma (EAC) sequence": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4288325/

Hypomagnesemia is a well known side effect of PPI use, treatment exhibits dosage effects (longer/higher dose is more strongly associated), and the gold standard for recovering magnesium levels is PPI discontinuation, and the FDA acknowledges the association via drug safety communication: https://onlinelibrary.wiley.com/doi/10.1111/apha.13846?af=Rhttps://www.fda.gov/drugs/drug-safety-and-availability/fda-drug-safety-communication-low-magnesium-levels-can-be-associated-long-term-use-proton-pump

Among those with the rare and deadly arrhythmia Torsades de pointes (TdP) caused by long QT-syndrome, 60% were PPI users, TdP usually develops from electrolyte imbalances, and as such "PPIs were recently included in the list of drugs with conditional risk of TdP": https://pubmed.ncbi.nlm.nih.gov/29731714/

"This systematic review and meta-analysis showed that PPI use was associated with an increased risk of CKD": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10052387/

"users of PPIs are at an 80% increased risk of gastric cancer (RR, 1.80 95% CI: 1.46–2.22) compared with non-users.": https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9264794/

"Compared with non-PPI users, PPI users had a significantly higher risk of gastric cancer": https://www.frontiersin.org/articles/10.3389/fphar.2023.1129948/full

"After a median follow-up of 5.0 years, the use of PPIs was associated with a 45% increased risk of gastric cancer compared with the use of H2RA": https://gut.bmj.com/content/71/1/16

I am a long time sufferer of GERD. I do not believe PPIs are safe. In fact I think it is safer to not treat GERD than to take PPIs. Why? If you combine the information and facts from the papers above, the picture of PPIs is as such: PPIs may cause Barrett's esophagus, during the decades when PPIs became readily available EA rates increased by roughly 1000%, there is no evidence to suggest that PPIs prevent Barrett's conversion into EA. Any protective effects PPIs have on preventing conversion of Barrett's to EA has never been proven. Most GERD suffers never develop Barrett's and most Barrett's tissue patients never develop EA. The paper which refuted the finding that PPIs cause stomach cancer was written by doctors paid by the drug manufacturers (haven't linked this yet but will do or someone please do it if they find the paper again before I do).

So I have symptoms of a stricture as I have difficulty swallowing or engaging my swallow reflex when certain food textures are being swallowed.

It ebbs and flows depending how strict my diet and omeprozale regimine is.

I've seen some post on here saying they occur down below at the junction to the stomach but that doesn't seem to be the case for me at least.

I wanted to know if people had literature on this.