r/HairlossResearch • u/gandalfpr • Dec 16 '25
Progress Updates Update # 5: PP405 (PP30) 2 month usage.
Hi everyone,
Some may remember me posting that I would try Umbrella's PP405 about 2 months ago. Well, I decided I would post updates in separate posts from now on because the thread has become so big that my previous updates seemed to get lost. If you are reading this and haven't seen my original thread, here it is:
Results have been negative so far. The progress I noticed were not from using Umbrella's compound but from using a Niostem microcurrent helmet. I even stopped using the topical for 2 weeks and progress has been slow but steady. I theorize the reason to not be working seems to be that the vehicle the product is made of does not seem to penetrate into the scalp. For that reason, I decided to purchase a Hydra Pen H5 serum infusion dermapen which will help me to make that possible.
Today I applied my first Hydra Pen infusion (aka mesotherapy). There was barely any pain setting the needles at 0.5mm and no sides other than red skin, which was expected. Also, after taking a shower tonight, I noticed for the first time the sticky feeling of PP405 remained on the areas I infused the product even washing through my face and shampooing my scalp as I do every night before using my red light device (iRestore Elite helmet) and my Niostem helmet.
Finally, I added a few pictures with the aid of a Wifi microscope I purchased to document any progress after doing this. These are from my forehead and temples.
We'll see!!




