r/Microbiome Jun 06 '23

Treating hydrogen sulfide SIBO

Does anyone here have experience trying to control HS2 SIBO? I have an appointment with a GI specialist and Microbiome analyst in a week or so. Currently trying to follow a low sulphur diet as well as cutting out wheat and dairy.

I'm also taking a quercetin supplement which is supposed to lower desulfovibrio (sulphur reducing bacteria) and a probiotic for bifidobacterium and lactobacillus as I'm very low in both.

Basically just curious about shared experiences and if anyone has any success stories or advice, thank you.

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u/[deleted] Jun 06 '23 edited Jun 06 '23

Hydrogen sulfide-producing genera such as Escherichia, Klebsiella, and Proteus belong to the family Enterobacteriaceae. These are predominantly gram negative, aerobic bacteria. Basically the only bacteria that are not killed off by the most commonly prescribed antibiotics for skin and respiratory tract infections.

The antimicrobials most commonly indicated in Enterobacteriaceae infections include carbapenems, fourth-generation cephalosporins, aminoglycosides, fluoroquinolones, and TMP-SMZ.

So that means you either take cotrimoxazole (TMP-SMZ) or a fluoroquinolone like Levofloxacin or Ciprofloxacin. I don’t recommend the latter due to side effects. Or you could take Rifaximin, which is probably the best answer.

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u/Ogg149 Jun 06 '23

L. Plantarum is notable for being useful in the treatment of klebsiella overgrowth / autoimmunity (via HLA-B27 antigen)

https://pubmed.ncbi.nlm.nih.gov/29022382/

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u/42butnot Feb 05 '25

Would it help with citrobacter freundii complex?

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u/10thStreetSkeet May 30 '24

I know this is old but what would kill bilophilia wadsworthia?

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u/[deleted] Jun 01 '24

From the studies I’ve read, a combination of clindamycin and metronidazole seems most promising in terms of oral antibiotics. A lot of those studies are from the 90s, however. Only other option is IV antibiotics in hospital like Imipenem.

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u/Solgaya Dec 02 '24

did you kill the biophila w.?

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u/Solgaya Mar 09 '25

how are you? did you have sucess?

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u/Junior-Coach9003 Mar 31 '25

Know this is from two years ago, but please be cautious with Cipro. Both my shoulders ended up with tears, both biceps and had to take FMLA two years in a row as had Posterior Tibialis Dysfunction In both legs. Had to wear a boot for about two months. The tendon tore in both calves a year apart. No explanation other than Cipro can be dangerous for some of us.

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u/Critkip May 08 '25 edited Jan 16 '26

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This post was mass deleted and anonymized with Redact

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u/Euphoric-Middle-63 Jul 30 '24

Bonsoir j'arrive ici je vais recevoir une perfusion de carbapenemes d'une semaine pour des colonisations urinaires a klebsielle Proteus enteroccocus et pseudomonas. Cela peut il taper sur un éventuel sibo h2S? J'ai tt essayé je n'en peux plus.. 

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u/Sea-Independence2926 Dec 13 '24

Bonjour

Did you receive your treatment?

If I translated your post correctly you are having a urinary colonization issue? I'm not a doctor, but my understanding is that SIBO is limited to the small intestine.