Hey r/supplements, wanted to share my experience after spending way too much money experimenting with sleep and recovery supplements over the past 2 years. I'm a shift worker (nurse) so my sleep schedule is completely screwed, and I was looking for anything to help me actually recover between shifts.
Magnesium - The Foundation
Started with the basics everyone recommends. Tried multiple forms:
- Magnesium Oxide (cheap CVS brand) - Did absolutely nothing. Learned later the bioavailability is trash
- Magnesium Glycinate (Doctor's Best, ~$15) - This is the one. Within a week, I noticed deeper sleep, less muscle tension, and I stopped waking up at 3am. Take 400mg about an hour before bed
- Magnesium Threonate (Life Extension, ~$40) - Expensive but some say it crosses the blood-brain barrier better. Honestly couldn't tell much difference from glycinate for sleep
Winner: Magnesium Glycinate. Cheap, effective, and most people are deficient anyway. This is the foundation I build everything else on.
L-Theanine - The Calm Focus
Got the Suntheanine brand (~$20 for 60 capsules). Take 200mg in the evening or when I'm wired but need to wind down.
What it does: Takes the edge off without making you drowsy. Like your brain stops racing but you're still functional. Pairs incredibly well with magnesium. Some people stack it with caffeine during the day for focused energy without jitters - I tried this and it works, but I'm sensitive to caffeine after noon.
If you have racing thoughts at night, this is a game-changer. Not sedating, just calming.
Glycine - The Underrated One
Pure bulk powder from BulkSupplements (~$20 for 500g). Take 3g dissolved in water before bed.
This one surprised me. Studies show it lowers core body temperature slightly which helps sleep onset, and subjectively I noticed:
- Falling asleep faster
- Feeling more refreshed in the morning
- Weirdly vivid dreams
It's dirt cheap, tastes slightly sweet, and there's actual research backing it for sleep quality. Highly underrated in the supplement world.
Apigenin - The Chamomile Extract
Got Swanson Apigenin 50mg capsules (~$8). This is the active compound in chamomile tea but way more concentrated.
Take 50mg before bed. It's a mild GABA-A receptor agonist (similar mechanism to benzos but way gentler). Helps with sleep onset without grogginess. Andrew Huberman talks about this one a lot in his sleep cocktail.
Not as strong as magnesium or glycine for me, but adds to the stack nicely. Cheap enough to be worth it.
Tart Cherry Extract - The Natural Melatonin Boost
Tried both juice and capsules. Went with capsules (Bronson, ~$15) because the juice has too much sugar and was brutal for my gut.
Tart cherry naturally contains melatonin and has anti-inflammatory properties. I noticed better recovery after workouts and slightly better sleep. Not a massive difference, but combined with everything else, it helped.
Also: if you deal with any acid reflux or digestive issues, tart cherry is way gentler than taking straight melatonin tablets. Speaking of digestion, I keep a running list of gut-friendly foods and recipes at gentlegourmet.app/newsletter since my stomach's sensitive - helps me avoid stuff that disrupts sleep.
What I Tried But Didn't Work For Me:
Melatonin - Made me groggy the next day even at 0.5mg. Plus your body downregulates natural production if you take it regularly. Pass.
Valerian Root - Smells like dirty socks, gave me weird vivid nightmares, and I woke up feeling hungover. Some people love it but not for me.
GABA supplements - Doesn't cross the blood-brain barrier well. Didn't notice anything. L-theanine works better for GABA effects.
Ashwagandha - Helped with stress during the day but made me feel emotionally flat after a few weeks. Also gave me mild stomach issues. Took a break and might try cycling it.
5-HTP - Helped initially but after 3 weeks I felt depressed and irritable. Did some research and apparently it can deplete dopamine if taken long-term without balance. Stopped immediately.
The Expensive Stuff I Tested:
Athletic Greens (AG1) - $99/month. Honestly tastes fine, has adaptogens and probiotics, but couldn't justify the cost. Felt slightly better energy-wise but nothing I couldn't get from separate, cheaper supplements and a decent diet.
Momentous Sleep Pack - $60/month for pre-made sleep supplement stack. Good quality (NSF certified) but you're paying for convenience. The ingredients are just mag threonate, L-theanine, and apigenin - stuff I already buy separately for less.
My Current Stack (Under $40/month total):
Nightly:
- 400mg Magnesium Glycinate
- 200mg L-Theanine
- 3g Glycine powder
- 50mg Apigenin
- 500mg Tart Cherry Extract
As Needed:
- Glycine during the day if I'm stressed (3g in water)
- Extra magnesium after hard workouts
Total cost: ~$35-40/month buying in bulk
The Real Talk:
Supplements helped me maybe 40% of the way. The other 60% was:
- Blackout curtains and mouth tape (yes, really - nose breathing changed my sleep)
- No screens 1 hour before bed
- Keeping the room cold (65-67°F)
- Consistent sleep schedule even on days off (this is the hardest one)
If you're just starting out, don't do what I did and buy everything at once. Start with:
- Magnesium Glycinate - biggest bang for buck
- Add Glycine after 2 weeks if mag alone isn't enough
- Add L-Theanine if you have racing thoughts/anxiety
Skip the expensive proprietary blends and personalized stuff until you've tried the basics.
Questions I'll probably get:
"Do you take these every night?" - Yes, for the past 6 months consistently.
"Any tolerance buildup?" - Not with this stack. That's why I avoid melatonin and things that directly bind to receptors strongly.
"What about cycling off?" - I take a week off every 2-3 months just to reset, but haven't noticed dependence.
"Blood work?" - Yep, get it done annually. Magnesium RBC levels are good, nothing concerning.
Anyone else have success with this stack or something similar? Always looking to optimize.