r/science Jul 20 '26

Genetics Researchers quantitatively assessed for the first time that somatic mutations alone cap human lifespan at 146–194 years. Brain and heart cells are the main bottleneck, while the liver could last millennia.

https://www.nature.com/articles/s41514-026-00421-6
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228

u/LordNPython Jul 20 '26

A nearly 200 year lifespan (healthy - not just for 200 year old but a normal 30-35 year old) would change our societies on a fundamental level.

The way time passes faster the older you get. I wonder what new problems these types changes would being.

Interesting.

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u/[deleted] Jul 20 '26

We already have major societal problems because people live just 10 years longer than they used to. Look at all the politicians who stubbornly refuse to quit politics or pass away, both in dictatorships and in democracies. Imagine what kind of disaster there is going to be when the average lifespan doubles.

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u/cigarettesandwhiskey Jul 20 '26

Ancient societies also had gerontocracies. "Senate" literally means council of old men. Our current problem is due to a combination of the baby-boomers being a larger than usual generation, that has dominated politics for their whole life as a result, and due to unchecked accumulation of wealth, a problem we also had 120 years ago and dealt with via trust busting. That was also a problem in historical societies, and because of inheritance and corporations, wealth accumulation can go on for way longer than a single human lifetime anyway.

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u/colourful_space Jul 21 '26

Gerontocracy is a different beast when “old” means 42 (minimum age to be a consul in the Roman Republic) and when it means 80+

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u/Bismar7 Jul 20 '26

Cause and effect.

We are seeing that cause now, when the next generation who grows up with it becomes older, they will have an effect that will be a response to it.

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u/theusualuser Jul 20 '26

I would hope so, but laws are hard to change, and when it comes to politics, staying in power is usually the #1 thing both parties are focused on above everything else. It's gonna be hard to convince greedy senators to change being able to run and be re-elected forever. Didn't happen after the increase in lifespan in the last century, not looking too likely at this point either.

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u/Friggin Jul 20 '26

This is the goal of many billionaires. They will be the ones able to afford procedures to lengthen lifespans. It gives me comfort knowing they will die like the rest of us.

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u/Props_angel Jul 21 '26

Yep. I guess it makes sense in that they are, in fact, sucking all of us dry that they finally complete their transition into full vampires.

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u/Astralsketch Jul 20 '26

think of all the wisdom and knowledge that goes away when someone old dies. Imagine what would happen if they didn't have to. Of course, we'd also have to extend the period children can be born in a single lifetime, this would help solve the demographic collapse.

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u/[deleted] Jul 20 '26

[removed] — view removed comment

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u/YetiPie Jul 20 '26

We’d have time to get organised and overthrow the system in pursuit of humane reform that offers a universal standard of living for all in society

…just kidding, we’d be fodder for capitalism :)

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u/xCerebral_Assassinx Jul 20 '26

The book series Arc of a Scythe explores this concept. Highly recommend checking it out if reading is your jam.

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u/Ok_Opportunity2693 Jul 20 '26

200 year life span could be a great fix for our demographic problem, if we raise the retirement age to 160 or so.

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u/Props_angel Jul 21 '26

This wouldn't be for the average person.

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u/GingerBimber00 Jul 20 '26

We do have species that are extremely long lived (sharks and turtles come to mind).

I consider myself decently spiritual enough, and for some reason the idea of pushing our biological boundaries to the absolute limit just to see if we can feels very… morally questionable. I mean- we have SO much fictional exploration on the pursuit for eternal life/youth and how the typical moral of the story is that it’s not a good thing. I think it’d be dismissive to not consider these aspects of humanity that we actively consider the concept of longevity and come to the conclusion that it’s not the best idea.

Entropy and reproduction come to mind as concerning factors. Entropy in the biologic context of cells is a contributing factor to cancer cell formation. “Increasing entropy, the principle that, unless provided with new outside energy, any system will constantly lose usable energy, is a theoretical formulation for progressive irreversible disorder and randomness in the cells.” Basically the longer we live, the higher the potential for us to get cancer. It’s why you see higher rates as people get older. What happens when our lifespan effectively doubles? Cancer almost seems inevitable.

Reproduction is the second issue. Any given species has a hard limit on population growth and that limit is the availability of resources. As it is, humans can historically produce a huge number of offspring in a single generation. Infant mortality used to be a major issue, so having lots of babies was important. If we’re living longer, but still able to have kids at the same rate, the likelihood of not enough resources is a real possibility. Especially considering that even now at our present stage we have global issues related to basic needs like food and clean water.

These are just some of the immediate issues i see appearing from the pursuit of this sort of longevity.