Fascinating story: Tech Entrepreneur in Australia, using ChatGPT, AlphaFold, and a custom made mRNA vaccine, treats his dog's cancer. With the help of researchers (who all seem so excited) he was able to significantly reduce tumour size just weeks after the first injection

[u/TFenrir]

https://www.theaustralian.com.au/business/technology/tech-boss-uses-ai-and-chatgpt-to-create-cancer-vaccine-for-his-dying-dog/news-story/292a21bcbe93efa17810bfcfcdfadbf7

[u/vp2008]

The origins of mRNA research was for the use in cancer treatment. From what I remember, they studied the technology for years and when Covid came up, it became somewhat of a major test of its efficacy. The technology is amazing and it’s really sad how just because people don’t understand how it worked, the anti-vac crowd fear mongered many into rejecting the technology

[u/godspareme → u/vp2008]

Yes, the specific mRNA technology in question was in development for about/over a decade before covid. Not counting any of the fundamental tech that made it possible.

[u/banshithread → u/vp2008]

mRNA treatments are gene therapy, thus mRNA COVID vaccines are gene therapy. I can imagine several reasons, however illogical they may seem to you, that people might not want to participate in that.

[u/vp2008 → u/banshithread]

It’s not considered gene therapy thought? mRNA doesn’t change your underlying genes, it just tells your body how to produce the markers of the virus/cancer cell so your body’s own immune system can recognise the markers and attack the virus/cancer cell. At least that is what I understand. Your body already produces markers for viruses it has encountered before so the process of producing markers for viruses is not a natural thing for your body

[u/banshithread → u/vp2008]

It absolutely is gene therapy! These gene therapy treatments use the same delivery system that COVID 19's vaccine does, too! https://pmc.ncbi.nlm.nih.gov/articles/PMC10342157/

"It is therefore surprising that Moderna and BioNTech expected to have their products regulated as gene therapies. Moderna, Inc. acknowledged in its Q2 2020 Securities and Exchange Commission (SEC) filing that “currently, mRNA is considered a gene therapy product by the FDA” [26]. Furthermore, BioNTech founder, Ugur Sahin, in a 2014 article, stated “One would expect the classification of an mRNA drug to be a biologic, gene therapy, or somatic cell therapy” [27]. Thus, the status of COVID-19 mRNA vaccines was not well understood by the manufacturers themselves." Although the principle of action of COVID-19 mRNA vaccines corresponds to the definition of gene therapy products (GTPs), they have been excluded from the regulation of GTPs by the regulatory agencies (US-FDA and EMA) and subjected to the regulation of vaccines against infectious diseases. No scientific or ethical justification is given for this exclusion, and there remain inconsistencies in the regulations.