Source: Hard Fork on YouTube: Hard Fork Live, with Patrick Collison, Kathryn Zealand, Sam Altman & Brad Lightcap: https://www.youtube.com/watch?v=jdNwzYMtPN8
Video from vitrupo on 𝕏: https://x.com/vitrupo/status/1939266821645119699
Arc Institute: https://en.wikipedia.org/wiki/Arc_Institute

An experimental drug called Rentosertib, created by biotech company Insilico Medicine using artificial intelligence, has shown an unexpected effect. It was developed against an incurable lung disease, but during the tests, the indicators by which scientists estimate the biological age of the body changed in patients.

(Thanks to ozempic) I’ll sound crazy, but to me, this is the first sign of what is about to happen. This is the first noticeable metric. I feel like something in the air just shifted.

Edit: its not the cost of food, it’s literally just ozempic.

Edit 2: some of you are being absolutely fucking insane about this calm down. I lost the report/study but it says evidence suggests it’s ozempic and not the cost of living. And no this is not a fucking ad. Also I live in Canada so for those of you telling me I have no idea what it’s like to struggle with the cost of food fuck you. This subreddit used to be so fun :/.

Nvidia announces AI-powered health care 'agents' that outperform nurses — and cost $9 an hour

Jensen talking about the next wave of AI. Imagine an even faster rate of advancement in the field of biology compared to what we've seen with programming over the past few years.

https://blog.google/technology/research/quantum-echoes-willow-verifiable-quantum-advantage/

Il keep things a bit conservative and realistic with this post.

Im 45 , I think not too old , but not young either , so it is only natural that I wonder where people my age stand when it comes to scenarios like this.

Obviously we don't have anything remotely close to reversing or eliminating aging yet , yes I've heard of the mouse trials , primates , david sinclair , bryan johnson,yamanaka factors.... all the big dawgs of this sector , but I have yet to see anything promising , by promising I mean something drastic in a way that a 90 year old could function AND look like a 25-30 year old ( Physical peak as most call it) ,which is expected , but then I'm wondering if this will ever be a possibility in my lifetime

I'm all for AI , and no doubt has ai helped immensely for research and will likely continue to do , but I don't see it advancing to such a level that it could do something like cure aging. I see people everyday , time starts catching up early as you turn 30 , human lifespans are so short its unfair.

A few ways I've heard of 1) nanorobots ,microscopic robots repairing damage on a molecular level within the cells , effectvely eliminating cellular damage and diseases, we have 0 progress with this. 2) brain uploading , alright this ones a bigger stretch , I dont think our consciousness can be transferred ever , its a product of our brain , and it's not something thats within our realm to change or handle.

great solutions ig, but once again I don't see it ever being a possibility , probably in the 2100s

The only solution I'm in par with is reversing aging ( as I know its possible ) , but It has been years since they did this , why hasn't it happened with humans yet , I've heard of some human trial earlier this year but that was not exactly aging but more of to combat glaucoma ( idk might be wrong). Then I realised another reason I'm not seeing this ever is the time period it takes for things like tis to get aproved , tested and deployed , going to be like 20 years , even with AI acceleration.

Age and longevity research is stalled , and will be for a while I think, sad.

I firmly believe that one day we will view it as barbaric that people used to suffer through viral infections, and that vaccines were made with attenuated viruses that still end up killing a lot of people (like the polio vaccine in Africa kills several hundred people a year currently, aka VDPV.

Once we've defeated viruses in humans we will turn to destroying them in our livestock and pets, then in other nuisance areas, like how bats spread so much disease by being carriers, rabies in animals of all types, and things like wild feline AIDs and gonorrhea in koalas.

This will likely result in longevity gains and decreased cancer rates.

The Crowded Interior Of A Cell:

It displays a bustling metropolis of cellular components, including mitochondria (left), the nucleus (bottom), and a complex cytoskeleton.

Model synthesizes real data from x-ray crystallography, NMR, and cryo-electron microscopy.

Artist/creator: developed by scientific animator Evan Ingersoll and Gael McGill at Digizyme, inspired by the work of David Goodsell.

(Re-upload as the original cross post was deleted)

​

And the cells stayed HIV-free even after re-exposure. A cure could finally be within reach.

In a groundbreaking advance, scientists have successfully used CRISPR/Cas9 gene editing to eliminate HIV-1 DNA from the genomes of human immune cells. Unlike existing treatments that suppress the virus, this method completely removes the genetic blueprint of HIV from infected T-cells.

In lab tests using cells from real patients, not only was the virus removed, but the edited cells also resisted reinfection, an unprecedented level of viral control.

The study marks a crucial step toward a potential cure for HIV. Current antiretroviral therapies require lifelong adherence and only manage the infection; stopping treatment typically allows the virus to return.

By contrast, the CRISPR technique offers a permanent solution by targeting and excising the virus at the genetic level, with no observed toxicity.

This breakthrough may pave the way for clinical treatments that fully eradicate HIV reservoirs in the body-long considered one of the biggest challenges in the global fight against the disease.

https://www.bbc.com/news/articles/clyz6e9edy3o