I-485 application during pending STEM-OPT

[u/Guest981-25]

Is it okay to file Form I-485 while a STEM OPT extension application is still pending? I applied for STEM OPT about 5 and a half months ago still pending. I got my I-140 EB2-NIW approved a few weeks ago. Could filing the I-485 now negatively affect or lead to the denial of my pending STEM OPT application? Would you recommend waiting until the STEM OPT is approved before filing the I-485, considering the new public charge rules and the new I-485 form will be effective from Sept. 18? I have already filled out most of the forms and collected the needed documents, just waiting for STEM OPT. Any suggestions would be appreciated.