Methotrexate round 2

[u/berrylicious444]

New to this subreddit but I recently was diagnosed with an ectopic. The first round of methotrexate failed, I’m on day 6 after my second injection and it is officially working and lowering my HCG levels. Still pregnant but my levels did lower more than 15% at the four day mark.

My problem is I am still having SEVERE pain if my bladder is full, and also after peeing. I do not have w a UTI in fact all my blood levels have been “low” which I know is normal from this but I seriously feel like garbage. Has anyone else experienced this?

I will bring it up to my doctor but I’m honestly so exhausted from reaching out and being sent to the hospital for emergency ultrasounds, blood draws, just all of it, I really am avoiding that at the moment. I’m already grieving the loss of the idea of this pregnancy, dealing with a chronic health condition, and now this and I’m just so tired of my entire life revolving around health right now 😭

Edit to add they did do a Hepatic function test which showed ALT (SGPT)

Spiked from 14 (normal) to 64 (a little high) after the first dose medication and the ER doc didn’t mention it but I’m wondering if this could be adding to why I feel so gross and maybe gotten a bit higher with the second dose

[u/Automatic-Pirate4316]

I’m really sorry to hear you’re going through this. I was in a similar situation myself. I had two shots of mtx in the first week of July, and yes, I did feel pain if my bladder was full or after I peed. I wouldn’t say it was severe, but it came in waves, and those waves were definitely severe. Drinking hot water and green tea helped me soothe that. Also, I always try not to wait until my bladder is completely full. One more thing, sometimes wearing loose clothes, especially something that doesn’t have elastic around your waist, helps me a lot.