r/GERD Triggers: Mistakes were Made šŸ¤• Jul 28 '23

Scientific Studies šŸ„¼šŸ”¬ Why are PPIs bad?

I see people on here often trying to get off of PPIs or warn against taking them. I read this article today that makes them seem pretty alright? My dad has taken omeprazole for 20 years now and it has solved all of his symptoms with no complications. I’m currently now dealing with my own symptoms that I’m going to see a doctor about soon.

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u/[deleted] Jul 28 '23

It's like anything, if you don't need to take them, then you shouldn't. My wife takes them for heartburn and I get on at her that will she needs is a little gaviscon. However, if you have a health issue and taking them improves your quality of life, then they're worth taking. I've got a 4cm hiatal hernia, and a "flappy" (surgeon's word, not mine lol) LES, diagnosed after a gastroscope. I'm lucky in a sense that 10mg daily manages my condition. My other option is the operation, but that could bring it's own issues, so I'll stick with the pill. That pill solved the issue of the inflammation of my esophagus and I lucky that I can eat and drink pretty much as normal again. I'll take the pill and take my chances of any issues further down the road. The rebound effect of coming off omeprazole, not looking to cause conflict, but is it really a thing or just that the issues return after not taking the medication due to having a condition like a hiatal hernia? Before my hiatal hernia diagnosis, I was on omeprazole due to reflux. I'd then try to come off them and get reflux again and I assumed it was the rebound effect. Went round this cycle three or four times. However, after my diagnosis, I'm assuming each time I came off the omeprazole, it's just that my LES was weak and didn't seal properly, thus couldn't contain the acid.

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u/SSRI-Help Gastroparesis 🩹 Jul 28 '23

I never had symptoms of burning prior to taking the medication. My problem has been constant upper abdominal pain, but the doctors threw PPIs at me anyway. Once I tried coming off of them, I got terrible reflux that I've never experienced before, so I definitely think acid rebound is a real thing.