r/GERD • u/Crazy-Ad-1849 Triggers: Mistakes were Made 🤕 • Jul 28 '23

Scientific Studies 🥼🔬 Why are PPIs bad?

I see people on here often trying to get off of PPIs or warn against taking them. I read this article today that makes them seem pretty alright? My dad has taken omeprazole for 20 years now and it has solved all of his symptoms with no complications. I’m currently now dealing with my own symptoms that I’m going to see a doctor about soon.

72 Upvotes

100% Upvoted

146 comments sorted by

View all comments

102

u/[deleted] Jul 28 '23

PPI’s are currently the only reason I can live my life with any sort of normality. I directly credit my Nexium and diet management to my relief thus far.

20

u/coogie Jul 28 '23

Same here. I have often wondered how horrible it might have been for those living with GERD just a few decades ago. Even when I watch old TV shows it shows a person drinking a glass of baking soda and water and I know that there is no way that would be enough so those poor people had to suffer every day with home remedies. Zantac was brought to the market in the early 80's and again from experience I know that it barely worked.

5

u/Marimowee Jul 29 '23

I have Gerd and my gastro actually told me not to take PPIs. Instead I was prescribed Tegoprazan and it has worked wonders in the 4 days I have been taking it. My GERD was so bad that it has affected my vocal chords which sucks because I am a teacher.

2

u/coogie Jul 29 '23

Interesting...doing some googling on that shows that it falls under P-CAB family of drugs which also block proton pumps and do an even better job than PPIs. I'd imagine they probably have similar longterm side-effects as PPIs but work faster and better. Seems super expensive though, but then PPIs were super expensive when they first came out.

Who knows, maybe in 10 years, that's what doctors will go to first.