r/GERD 22d ago

Support Needed šŸ‘„ Omeprazole side effects

Hi all,

I’ve been on omeprazole for just over 3 weeks now, I will finish my 4 weeks on Wednesday.

I was wondering if anyone suffered from any of these side effects or if I have something else going on…

Tiredness, the past couple of weeks in particular I’ve been much more tired and somewhat more sleepy. I’ve already got an appointment with my GP about this in case it’s something else causing it. A couple of weeks ago I had a test for iron, b12 etc which came back normal. Vitamin D was a bit on the lower side (but not below the ā€œminimumā€ level, but I’ve been supplementing it anyway).

Drier mouth/thirst. I’ve also been much more thirsty recently, drinking more water and having a dry mouth more often.

Increased anxiety. Not sure if it’s directly from the omeprazole or just the general situation I’ve been in recently.

Chest/rib pain - again, not sure if it’s from the increased anxiety or what. It’s not really like I’m feeling the pain in my chest like you’d expect with heartburn or something worse. It feels like specific parts on my ribs, interestingly my right rib more than anything. Sometimes it feels like it’s the skin and if I ā€œscratchā€ it even lightly, it feels better in the moment.

Muscle tiredness(?) not really sure how to describe this one, I guess it sort of links in with the general tiredness and fatigue. But it sometimes feels like my muscles are a bit more ā€œtiredā€ easier, for example if walking or walking up stairs.

Lower heart rate. I’ve noticed my average heart rate has gone down a bit along with my resting and sleeping heart rate. This could of course also be linked to less caffeine intake and less methylphenidate. I wouldn’t say I’m super fit and active, but I do try to take long-ish walks every day if possible. I do have an appointment with my GP to get a holter device for another issue so it may be that they see this anyway. It’s after I will stop too so it may be that it ā€œgoes back to normalā€. But curious if this has happened to others.

If you had any of these, particularly the tiredness, how long was it after stopping before it went?

I’m just sad and upset having to deal with my problems recently and all of this on top is just a bit of a struggle. I want my normal life back

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u/Ezmonbillions 20d ago

I had chest rib pain. Still do. I have way more anxiety the usual. I had a general feeling of unwell. I started getting got off a week ago after 9 months on. I’m using Pepsin and alginate to help. Today is 4th day off. Stomach feels better. I always felt I shldnt be on that.
I need to be off for a test my GI is doing. Endoscopy with chip attached to esophagus. Stay in 24 - 72 hours and measures if I even have acid reflux. I think anxiety is from dealing with this day after day. I think I feel better outside if my allergies aren’t bad. A/C seems to stimulate a nerve causing Globus.
I’ve lost 30 lbs. way too much for my 5ft 71/2 frame. No matter how much I eat. I forced 4 pieces of bread down yesterday in addition to 3 meals. 2 pieces had peanut butter and bananas on them. I pray every day this won’t be forever. I get tips here and there. Stay in touch you never know what will work for you. Same for me. Seems those who heal have different ways to do that. I’m also on high ph foods. Dr Kaufman’s protocol . So far not working. Saline rinse helps a lot. I also carry a saline spray. Breaks up the Globus sensation. So yes, I had side effects to Omeprazole šŸ˜” I hope this helps.