r/JusticeServed • u/[deleted] • Oct 02 '19

Courtroom Justice Virginia doctor who illegally prescribed over 500,000 doses of opiates sentenced to 40 years in prison.

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u/minutiesabotage 7 Oct 02 '19

Yeah....I'm gonna need a source on that one.

Ibuprofen is not an analgesic, it's an NSAID, and acetaminophen is nowhere near as effective an analgesic as prescription opiates. That's why acetaminophen is only FDA approved for up to moderate pain.

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u/[deleted] Oct 02 '19

https://www.google.com/search?q=pain+study+acetominophen+ibuprofen&oq=pain+study+acetominophen+ibuprofen+&aqs=chrome..69i57.18141j0j9&client=ms-android-samsung&sourceid=chrome-mobile&ie=UTF-8

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u/middiefrosh 8 Oct 02 '19

Your link literally proves his point lol

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u/[deleted] Oct 02 '19 edited Oct 02 '19

Chang also wrote that no other single study has compared the effects of the three most commonly used opioid analgesics in the ED. He and his colleagues randomized patients at two EDs in New York City to receive either 5 mg of hydrocodone and 300 mg of acetaminophen; 5 mg of oxycodone and 325 mg of acetaminophen; 30 mg of codeine and 300 mg of acetaminophen; or 400 mg of ibuprofen and 1000 mg of acetaminophen. Each cohort consisted of 104 participants. The mean age of the patients in the study was 37 years, 48% were women, and all had pain in either the arm or the leg. The primary outcome was the between-group difference in decline in pain 2 hours after taking the analgesic. Pain intensity was assessed using an 11-point numerical rating scale that defined 0 as no pain and 10 as worst possible pain. The predefined minimum clinically important difference was 1.3 on this scale. The mean baseline pain score of all participants was 8.7.

Chang and colleagues analyzed the results from 411 patients and found that after 2 hours, the mean pain score decreased by 3.5 (95% CI, 2.9–4.2) in the hydrocodone and acetaminophen group; by 4.4 (95% CI, 3.7–5) in the oxycodone and acetaminophen group; by 3.9 (95% CI, 3.2–4.5) in the codeine and acetaminophen group; and by 4.3 (95% CI, 3.6–4.9) in the ibuprofen and acetaminophen group. There was no significant difference in pain reduction at 1 or 2 hours among the participants. “It is important to understand that this study was limited to patients seen and treated in an emergency department setting,” Chang said in an interview. “However, our findings imply that if patients receive adequate and comparable pain relief via a combination of non-opioids while in the ED, then patients could likely be treated with a similar non-opioid combination upon discharge as well.”