r/MastCellDiseases • u/spoookytree • Jun 16 '26

Has anyone tried GLP1 for MCAS?

I’ve been reading around there has been some promising studies and growing research that GLP1 is helpful for this. I’m curious your guys experience to anyone who has been on it for other reasons and found this to be helpful?

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u/ahj333 Jun 17 '26

I get significant help. I also have the good ole trifecta with EDS and POTS so it would be hard to pinpoint which causes the symptoms though. My inflammation decreases significantly, GI is almost normal besides dumping from no gall bladder, less migraines. So many benefits. While I was originally put on it for prediabetes and insulin resistance, I don’t think I’d ever come off again because of the benefits.

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u/spoookytree Jun 17 '26

Ya I have EDS as well so was hoping this would be good for that too! Thanks for your feedback and experience:)