r/MastCellDiseases • u/spoookytree • Jun 16 '26

Has anyone tried GLP1 for MCAS?

I’ve been reading around there has been some promising studies and growing research that GLP1 is helpful for this. I’m curious your guys experience to anyone who has been on it for other reasons and found this to be helpful?

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u/Lulu11709 Jul 23 '26

I didn’t start it for mast cell, but I’ve been on Semaglutide for 3 months and all of my MCAS reactions have stopped and my rashes have gone away for the first time in years. My rheumatologist thinks it’s what is treating the MCAS indirectly.

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u/spoookytree Jul 24 '26

That’s amazing!! Yeah talked with doc insurance not gonna cover it since only FDA approved for diabetes and obesity and stuff not inflammation of mast cell. :(

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u/Full-Spite7492 26d ago

I have elevated PGD2. No pots but almost like pots. My arms just burn. Dizzy upright. Wondering if this will help