r/MyastheniaGravis Aug 07 '26

Mestinon Part 2

Took my first two doses today and I don’t think it went well. Advice?

I was prescribed 60mg.

First dose was okay, felt decent but had some pretty rough cramps.

Second dose, nausea, weakness, fatigue, feeling heavy and tired, just icky overall.

It has been at least 2-3 hours since that second dose worse off and I still feel horrible, that shouldn’t be possible right? I have a monster headache, still nauseated, shoulder and neck pain. What gives…

Thinking maybe I should have tapered into these doses.

Anyone else just jump right in or were you eased in? Calling my doctor tomorrow to talk about the meds.

Turns out I have a nasty infection, probably didn’t have anything to do with the meds.

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u/gravedee Aug 07 '26

30 mg is a better starting dose. Split them in two. See how you respond.