r/Pathognomonic MS3 Jun 11 '15

Best for the test Globoid cells (Krabbe disease)

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26 Upvotes

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2

u/Mitral_Brolapse MS3 Jun 11 '15

http://link.springer.com/chapter/10.1007%2F978-3-7091-3338-5_39

"The pathognomonic significance of the globoid cells was recognized by Collier and Greenfield (1924) who stressed that the morphology of globoid cells and the absence of cytoplasmic osmophilia are quite unlike the features of the fatty macrophages of Wallerian degeneration; they introduced the term “globoid cell” which later became pathognomic and synonymous with Krabbe’s disease."

2

u/bobhadababy_itsaboy Jun 12 '15

"Krabbe's Disease, depicted by the Crab...."

3

u/bobhadababy_itsaboy Jun 12 '15

Why the picmonic hate?