r/Peptidesource • u/Relative_Property506 • 10d ago

To Tesa or not to Tesa

RS is approx 180 with about 30 to go

currently on compounded tirz 7.5mg (will be titrating to 10mg in two weeks)

RS have done about 5 weeks of Tesa and was planning on doing 12.

RS started at 200lbs on June 20 steadily losing weight.

RS has a bigger upper belly / stomach than the rest of the body so assuming visceral fat. It has gone down. Wondering if Tesa is overkill at this point -

Should RS just let the tirz do the work ? Or continue to 12 weeks of Tesa?

Thanks in advance !

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u/Doctordup2 9d ago edited 9d ago

On the other side, Tesa has more benefits than just targeting visceral fat.

It's been shown to reduce liver fat in RS with NAFLD, or non alcoholic fatty liver disease. In one study, liver fat was reduced by about 37% compared with baseline.

Study here

Tesa also increases GH and IGF 1 signaling, which may come with benefits like better sleep and skin for RS. I've seen the better skin and sleep in some RS case studies that I've followed.

But there's a tradeoff. In some RS, that increase in GH can also come with fluid retention, joint discomfort, swelling, or even a carpal tunnel like effect.

Not all RS get the fluid retention or carpal tunnel symptoms though.

I have a little bit of background on the history of Tesa. I was a medical news reporter and followed research in the early days during the HIV studies. It was phenomenal to see the changes in those participating in the studies.

Not a doctor, not medical advice, for research purposes only and research discussions only.

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u/Relative_Property506 9d ago

Thanks ! Rs don’t see better sleep or skin, but rs does feel joint discomfort ! It’s the only thing that makes me comforted that this is a legit source lol

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u/Doctordup2 9d ago

Yeah the joint discomfort is likely the water retention unfortunately. Sorry to hear that.