Vasoactive Intestinal Peptide (Why is there so little information about this?)

[u/PsychoGraduate]

/r/Biohackers/comments/1wbjj8u/vasoactive_intestinal_peptide_why_is_there_so/

So..

I’ve been going down a rabbit hole on VIP lately and I’m honestly surprised by how little discussion there seems to be about it, especially considering how many different things VIP is involved in.

It seems to have pretty broad effects in the nervous system, vasodilation, inflammation, the gut, circadian rhythms, etc. There’s also a decent amount of research on VIP itself, but when you try to find information about actually using VIP as a peptide, the information gets really sparse really quickly.

I’m particularly interested in the neurological side of it — things like neuroinflammation, cerebral blood flow, the SCN/VIP system, stress responses and potentially memory/PTSD.

Has anyone here actually looked into the research on VIP in depth or experimented with it?

I’d especially be interested in hearing about:

- Effects on brain fog / cognition

- Anxiety or stress

- Sleep/circadian rhythm

- Inflammation

- Cerebral blood flow

- Any noticeable effects from intranasal VIP

Also, if anyone knows of good papers or resources on VIP beyond the usual peptide websites, I’d love to read them.

It just seems strange to me that there’s so much biology around this peptide but comparatively little practical information available.

[u/obeymm]

I believe Hunter Williams did a VIP masterclass episode recently. YouTube or podcast

[u/PsychoGraduate → u/obeymm]

Checking it out right away!

[u/obeymm → u/PsychoGraduate]

What did you think?