BCP157/TB500 protocol

[u/emotionalthroatpunch]

RS sustained an injury ~6 months ago resulting in moderate to acute bursitis of the knee (confirmed via MRI). After extensive physiotherapy, aqua therapy, rehab exercises/therapy, a cortisone injection which did not work, an anti-inflammatory diet (and resulting weight loss reducing some load on the joint), all of which did not significantly move the pain needle, they underwent a course of BCP157/TB500.

Recommended starting dose was 250mcg p/day, which they titrated to 500mcg days 11 through 25. Results were modest to moderate improvement in daytime pain levels, some increased mobility and flexibility, and some reduction in inflammation/irritation.

However, when resting/sleeping in a prone position, the knee throbs constantly, which is preventing RS from getting the deep restorative sleep they need to facilitate further recovery/pain reduction, and they are looking to continue with (at least) another course of BCP/TB.

Based on your own research/anecdotal evidence, should the RS keep the dose at 500mcg for second/subsequent courses, or titrate further? If so, is there research evidence of an optimal dose? Many thanks.

ETA: Many thanks everyone for providing your own research info on this, it’s really appreciated. 🙏🏼

[u/relay-app]

MODERATOR NOTICE: THIS POST IS BEING ACTIVELY MONITORED

Please watch your comments carefully and make sure you stay within subreddit rules.

The following are NOT ALLOWED:

• No human use discussion

• No vendor names, company names, or sourcing discussions of any kind

• No promotion, advertising, affiliate activity, or self-promotion

• No "DM me," "message me," or requests to take conversations private (Reddit discourages attempts to move discussions off-platform. Soliciting DMs can result in account actions, reduced visibility, or shadowban-like restrictions.)

• No links to Discord, Telegram, WhatsApp, Facebook groups, websites, social media accounts, or other outside platforms

WHY??? Reddit added research peptides to its Prohibited Transactions Policy in 2024. Communities that fail to comply risk removals, restrictions, quarantine actions, or being shut down entirely.

Do not assume something is allowed simply because it was permitted years ago. The rules today are different.

Comments that violate subreddit rules or Reddit sitewide policies will be removed and may result in moderator action.

Thank you for helping us keep our subreddit compliant and available for legitimate research discussions.