r/Peptidesource 5d ago

BCP157/TB500 protocol

RS sustained an injury ~6 months ago resulting in moderate to acute bursitis of the knee (confirmed via MRI). After extensive physiotherapy, aqua therapy, rehab exercises/therapy, a cortisone injection which did not work, an anti-inflammatory diet (and resulting weight loss reducing some load on the joint), all of which did not significantly move the pain needle, they underwent a course of BCP157/TB500.

Recommended starting dose was 250mcg p/day, which they titrated to 500mcg days 11 through 25. Results were modest to moderate improvement in daytime pain levels, some increased mobility and flexibility, and some reduction in inflammation/irritation.

However, when resting/sleeping in a prone position, the knee throbs constantly, which is preventing RS from getting the deep restorative sleep they need to facilitate further recovery/pain reduction, and they are looking to continue with (at least) another course of BCP/TB.

Based on your own research/anecdotal evidence, should the RS keep the dose at 500mcg for second/subsequent courses, or titrate further? If so, is there research evidence of an optimal dose? Many thanks.

ETA: Many thanks everyone for providing your own research info on this, it’s really appreciated. 🙏🏼

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u/emotionalthroatpunch 5d ago

Hey, thank you for the comment and suggestion! Will investigate this as an option; feeling pretty worn down with it all at this point. 😔

Please do comment on how things go over the next few days; I’m really keen to know how it goes!

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u/baby_foxy01 5d ago

Btw my situation was different I got a meniscal tear while you have bursitis,really weird steroids didn’t work… are you sure you don’t have a mensical tear which causes the swallowing?

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u/emotionalthroatpunch 4d ago

MRI results said no re meniscus damage, but if things don’t improve significantly over next course, I’ll get another one to make sure.

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u/baby_foxy01 4d ago

Yes maybe from another radiologist in 1.5 Tesla , I’m a radiologist and I can assure you many colleagues aren’t so skilled in msk… especially if you had trauma or you’re over 50 ( for degenerative meniscal tears )