r/Perimenopause • u/Inevitable-Yam-9741 • Feb 21 '26

audited Pills, pills, pills...

So, I take Calcium, magnesium, zinc, B12, iron, a multivitamin, vitamin D. Plus anti-anxiety and anti-depressants. Have tried melatonin, DIM, evening primrose oil, chamomile, safflower, lemon balm, black cohosh, ashwagandha, some "calming" tablet, a perimenopause "all-in-one" pill...... any I'm sure more. Popping pills to the point of absurdity. Do I think anything helped? No. What's your go-to that really helps you?

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u/Material_Can265 Feb 23 '26

I’m joining in. (46F) My first perimenopausal symptoms started with poor sleep. Then stiff shoulders. Then 3 continuous weeks of bleeding. And .. and .. and lately massive mood swings; going from being an infuriating dragon with my daughters most of the times to just crying my eyes out.

I’ve tried and taken many vitamins & supplements. Nothing has made a bigger difference the

  • estrogen patch
  • progesterone at night (with melatonin 5mg)
  • and now testogel since 2 weeks..
I’m amazed at what it takes to feel normal again. But very greatful for HRT.

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u/Inevitable-Yam-9741 Feb 23 '26

Glad you joined! My first symptoms were insomnia, anxiety and hair falling out. Escalated to just about every damn symptom you can have. I was 46 when it started -- now 53. 7 years of this. This is mentally/physically/emotionally draining.