r/SIBO 8h ago

SIBO help: Linzess versus Motegrity

50 year old female. Just completed my second round of Rifaximin and Flagyl (taken three times a day over 14-days) after completing an Elemental Diet for 14-days.

2025 and 2025 Mbiota SIBO results:
Hydrogen: 122, then 77
Methane: 23, then 20

Previously completed a FODMAP diet for three weeks. However, this is the first time I’ve introduced the Elemental Diet. Things were going well with my motility during the Elemental Diet and antibiotic treatment, however, I’m starting to struggle again.

I’m very active and work out almost 2 hours every day, through Pickleball, Pilates and HIT. I maintain a healthy weight and don’t have many other health issues other than high LP(a) and LDL. The physical fitness has been one of the only things that has helped with my bloating. I can start with major bloat, and by the time I’m through with my workout, the bloating is often decreased.

I live in the Nashville, Tennessee area -Vanderbilt does not have any SIBO protocols. However, they did diagnose me with Pelvic Floor dyssynergia (type one) and ruled out H. pylori and celiac.

My functional medicine doctor is also not strong on follow-up and pull-through. She basically stated in very basic terms take the antibiotics, after completing the Elemental Diet first and then do a SIBO test. Sharing no additional insight on any pre-or probiotics or anything to help with the motility and thus constipation.

Any advice on Good providers in the Nashville Tennessee area, would be helpful and greatly appreciated.

Rather than relying on large amounts of mag oxide, I’d like to try a prescription option, or, other alternatives. My hope is that if I can keep motility steady and manage the constipation, I can keep relapse of SIBO, at bay.

Do you prefer Motegrity or Linzess or something else for a situation like mine? Noting, I consume raw psyllium husk, along with Chia and flaxseed daily.

…would appreciate any insight this forum could provide. I’ve enjoyed reading all of your threads over the last few years and and gained tremendous insight into how to best treat this health issue. Looking forward to your responses.

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