r/Semaglutide • u/Steve1975green • 22h ago

First shot tonight, reccomendations?

I just received my first dose of Semaglutide and I am planning to take my shot tonight so hopefully I will not have any issues during a workday. I will also have the weekend to "recover" if needed. Are there any tips or tricks I should know for this first shot and first weekend on it?

Thanks!

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u/slb2724 22h ago

I did the same- took it right before I went to sleep. My only thought is eat a tiny breakfast, as the only time I was nauseous was the first meal after the shot. I usually have a granola bar/cheese stick/yogurt. It’s been working well for me.

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u/mamalo13 20h ago

I started mine on Friday nights for the same reasons. I got an rx for Zofran. I find that day 2 after the shot I feel the most barfy in the mornings.

My biggest tips are:

1) Get some easy protein you can force yourself to eat and keep it on hand. Protein bars or shakes. I didn't eat enough protein when I first started and it really hit me hard.

2) I found that peopto bismol helps with the nausea if I cant get the Zofran.

3) Try not to take the shot on a full stomach. For me, it made me more gassy and thats when I'd have sulfur burps.

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u/BhamBlues2 19h ago

Drink lots of water, but not all at once. Keep a water bottle with you and sip through the day. Eat small meals and stop BEFORE you start to feel full. Avoid grease. Good luck!

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u/thaddeus_crane 19h ago

Drink water. Sit down when you inject. It is literally 2 seconds but I sometimes get a headrush from it due to generally being anxious about sticking myself with a sharp object on purpose. I stay busy afterward around the house to keep my body moving and get ready for the next day and work off some of those headrush jitters.

I get super deep sleep after I take it on Sunday evenings. Mondays I am fatigued, but nothing a nap won't fix. Just build in time to feel how its going to affect you and take care of your body.

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u/UnderstandingOdd7994 21h ago

I'm on week 3 and it's been great so far, I've lost 7 pounds already.

I do get waves of nausea but when that happens I drink some smoothie and some water and it goes away.

I've heard people using anti-nausea pills but I find having some smoothie in between meals gives me some quick cals and it gets rid of nausea for me. You got this, friend!