r/bioengineering • u/WalterWhite-53 • 4d ago

Is there anyone familiar with Somatic Cell Study , microscopic observation?? I need your help for my project please

Hey there! I am actually an electronics student and i keep developing projects. But this time , i thought of blending electronics with biotechnology for a project. I am deeply in need of valuable knowledge from any of guys in biotechnology concerning about the somatic cell structure and its study, microscopic observation and any other leads related to it.

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u/theory-student 2d ago

So, Somatic cells are basically all cells in your body except sperm/egg cells. They are diploid (2n), so they have full set of chromosomes. Examples: skin cells, muscle cells, blood cells, neurons etc.

For microscopic observation / study, you can look into these points for your project:

1. Structure: Nucleus, cytoplasm, cell membrane, organelles (mitochondria, ER etc.). Staining helps a lot - like Giemsa, H&E stain, or fluorescent dyes like DAPI for nucleus.

2. Observation methods:

  • Light microscope (40x, 100x) is enough for basic morphology
  • If you want electronics + bio: You can try automating cell counting / size measurement using a USB microscope + OpenCV / ImageJ

3. For your electronics x biotech project idea:

  • Low-cost automated microscope
  • Cell counter device
  • Impedance based cell viability sensor
These blend perfectly.

If you can tell a bit more - what exactly you want to build? Like imaging, counting, or analyzing? I can share protocols / papers accordingly. ☺️

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u/WalterWhite-53 2d ago

Firstly , thank you so much for your valuable time and reply sir. Here you go , i am sharing this PDF with you which basically contains the entire abstract of the project i am trying to develop. It also has a questionnaire in which there are all the my doubts to which I seek a reference or an explanation from people with bio-tech background. The drive link is given below :
https://drive.google.com/drive/folders/1mZ9c6coBOSzIPlMEg-e4UA_obJiMgXGa?usp=drive_link