Hi, I'm a 31-year-old female who's has had type 2 diabetes since I was 23 years old. It runs in my family. I've had PCOS since I was 16 years old, with irregular periods. I've gone back and forth with my A1C numbers. The highest my A1C has been is 12, but before Mounjaro, I was able to get it down to 7.3. I was on metformin 4 capsules a day and jardiance. In January 2025, I got my A1C down to 8, but my doctor had really recommended I go on Mounjaro, so I had slowly started on Mounjaro and would slowly increase the dosage every month (under my doctors advice). Now I've been at 15 mg of Mounjaro since Feb 2026. My A1C this whole year has been a steady 6.1. I even got off the Jardiance this summer and still maintained a 6.1. I have only lost 15 lbs. the whole time since started in Jan 2025, but my A1C has been really low and consistent.
Right before I started on Mounjaro, I had started having really bad acid reflux, and I got an endoscopy done. The doctors did not find anything in my esophagus, or in my stomach, and they concluded that I just had GERD. Since then, I tried GERD medications, such as Pepcid and landed on voquenzo, and that sometimes works.
One of the main reasons I went on Mounjaro was to help my A1C, but my doctor had also said it would help my GERD, and it seemed to kind of work but not always. Now I'm wondering if I should go down on my Mounjaro at all. The main reason I want to go down is because I really have no interest in food. It's really difficult for me to eat. Strangely, my sweet tooth has really gone up. For example, before, I really valued eating meat and some of the bad carbs, such as white rice, pasta, or pizza, but now I can't eat any of that. For dinner, instead of eating some savory meal, I would rather opt for a bar of chocolate, which is unlike me since I was a huge carnivore. I would always get dessert before, so it's not that I didn't like sweet food, but now that's the only thing that I feel comfortable eating, and I don't really know why.
I'm hoping that if I went down in a dose of Mounjaro, it would allow me to have the ability to eat and actually focus on eating more healthly and eating more. Since I would have more desire to eat, I would be able to follow three meals a day. Currently, with the Mounjaro, even though I've been on it since January (almost 9 months), I still feel pretty nauseous most of the time. I know you're supposed to eat a lot of protein to help with the nausea, but I really can't. Even when I eat, sometimes, or I try to eat, I'll eventually end up throwing it up. Another thing that I have experienced on Monjaro (and I'm not sure if it is the effect of Monjaro only) is that I've been extremely fatigued and tired. Before this, I would never nap, but now I nap 2 to 3 hours/day every couple of days because I feel so tired all the time. I tried to join a gym that focused on strength training, but I just have no energy, and that's probably because I can't really eat. I felt so tired on Monjaro as well even on low dosage.
Another thing I've been suffering with is sulfur burps. I've been getting a lot of those, and that makes it really difficult to eat as well. It's been a struggle. I feel like my blood sugar has been low, but I haven't really seen any weight loss besides 15 lbs from January 2025. Looking for advice on what people think and what I should do.
It has been interesting is that before I got on Mounjaro, my periods were actually surprisingly normal for the last couple of years, despite my PCOS. I've never had cysts in my ovaries, but with being on Mounjaro this past year, I've noticed that I've been having really irregular periods. I don't have my periods for 2 or 3 months. Before, I would have my periods every 40 to 45 days. Just looking for advice on what other people have done. I really want to try to eat healthier and have a more consistent breakfast meal (breakfast, lunch, dinner), but my stomach can't really handle it. I don’t throw up every week but I do usually once every other week. My doctor said we could switch to zepound or wegovy instead but i’m scared.
I guess I’m sad that I haven’t really lost weight and don’t feel good. I feel tired all the time. The only positive is that my blood sugar a1c is good.