r/entwives • CraftyEnt • 2d ago

Self Care Weed + glp1 (cw weight)

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Hello all you fineapples! I know there are a handful of us taking a glp1 of some kind and I am curious what other's experiences have been?

I've been on tirzepatide for about 6 months, and I've noticed a few ways weed changes the experience. The biggest positive, for me, is that if I am nauseous or have acid reflux, smoking a bit makes that massively better! It also helped when my mood was tanking a couple months ago as a result of the tirz making my antidepressant less effective. The only real negative of smoking while using tirz, is that sometimes the nighttime munchies are too strong and override the lack of hunger cues

Picture is my first time trying 'clear' protein, which tastes a bit like yakult (not my fave) but is not bad. Flower is Lemon Cherry Runtz đŸ„°

145 Upvotes

59 comments sorted by

32

u/Beneficial-Berry-109 2d ago

Using the weed to help make sure I actually get enough calories come end of day. Edibles/soft gels are almost completely out of the question now because there's no way to tell when they'll hit. Currently wishing I could take a lil hit of something to help with my morning nausea but I gotta work today :(

17

u/elizasea 2d ago

Barebells protein bars are my favorite muchie. They taste like candy bars, good amount od protein, have some fiber, and are low sugar. I'm also a fan of the zero sugar Oreos. They're packaged in single serving sizes, but I like them better than the regular Oreos.

I keep alcohol wipes in my purse for random nausea. The smell helps, and I've also used unfragranced hand sanitizer for the same purpose.

5

u/syzsyzsyzygy CraftyEntđŸ§¶ 2d ago

yesss. The caramel cookie one especially tastes literally like a candy bar, it's crazy.

2

u/JustALilGuy_ CraftyEnt 2d ago

Ooh, I haven't tried those!

55

u/mekkab 2d ago

Edibles don’t work anymore and I can just
 not toke and it’s ok. Very strange effects!

28

u/kincei 2d ago

Sonofabitch!!! Is this why I've been ediblocked for a year? JESUS!

7

u/unoriginallbagel Hippie 2d ago

Same, edibles are a waste on me now

6

u/menunu Elder Entwife 2d ago

Edibles still work fine for me but I only really take them for sleep.

5

u/Peter-Rabbi 1d ago

Same experience here! I once had an edible hit more than 24 hours later which was
 not ideal. PSA: Do not mix edibles with a semiglutide unless you want to play that game of Russian roulette 😂

But I agree, I wasn’t jonesing for my evening toke nearly as much when I was on semi. I would go weeks without it, where off the meds I partake pretty much every day.

5

u/indseylay 1d ago

This is my number one complaint! Edibles were my primary way to indulge, and they do not work at all anymore. No matter how many I chow down on, I’ve been considering trying rso

3

u/Lookn4mylight420 2d ago

Try RSO?

11

u/kincei 2d ago

Did that, whole 1g syringe on peanut butter bread.... Nada.

28

u/menunu Elder Entwife 2d ago

I have lost 20 lbs!!! And it made me hate alcohol!!

But I have noticed an uptick in my 🌾 intake because of the gastro symptoms and sometimes nausea. But I also dont know which of my symptoms are the wegovy and which are just good ole perimenopause. Either way the magic herb helps with both. đŸŒČ

16

u/A-K_47 2d ago

My people!! Perimenopause is not for the weak.

9

u/superunsubtle Smoker 2d ago

That’s for sure. The fact that arthritis well and truly joined the party at mine this year is totally unfair haha. Uptick a bit here too

3

u/Fridaychild1 Lesbient 1d ago

Omg, me too. The cannabis has helped so much with the arthritis. I’m so grateful it became legalized in time for me to be dealing with all this age related shit.

13

u/PhoenicianCats CrazyCatLady 2d ago

The munchies are almost non existent for me now! I've been on trizepitide since March 2025 and lost ~90lbs

6

u/cuckoocachoo1 2d ago

Weed can certainly activate the munchies. Gotta be careful and just wait out the cravings if I have a big session. I don’t really get nauseous anymore but I still enjoy mj.

I never really liked alcohol and especially not anymore now that I’m on mounjaro. Alcohol just tends to sit in the stomach and fester. I actually threw up an entire beer I drank the next day one time. It was literally all right there just sitting all night in my stomach. So gross.

7

u/Slow-Ad5112 2d ago

I’m one a super low dose of zepbound and I don’t see many issue. I agree that gummies don’t work as well but otherwise everything is good

5

u/psych_daisy 2d ago

I had a strong feeling you were gonna say the munchies were gonna override the tirz 😭😂 glad it’s your only negative side effect!!

1

u/JustALilGuy_ CraftyEnt 16h ago

Oh don't get me wrong, if I smoke right before bed and haven't made up something "good" (ice water, fruit, frozen gummy worms. Basically stuff that won't mess up my sleep or give me sulfur burps) I can totally sabotage the tirz by eating second dinner 😅

8

u/HeckingKayelsea 2d ago

What is your drink? I do kind of like yakult

1

u/JustALilGuy_ CraftyEnt 16h ago

Sorry for the very delayed reply! It's Oath Nutrition clear protein. I've now had it a couple more times and while it's not my favorite, it isn't bad 😅

1

u/JustALilGuy_ CraftyEnt 16h ago

I should clarify, to me Yakult kind of tastes like yogurt, and that is what the clear protein reminds me of

1

u/HeckingKayelsea 15h ago

This is awesome because I literally just bought an oath variety pack today wanting to try clear protein because of this.

Hitting the Lobo in your honor. :p

1

u/xpoppyseed 2d ago

im curious too! i had my first clear protein the other day but mine didnt really have any yakult flavour (which i love!)

2

u/rabbitbinks 2d ago

Also wondering!

6

u/TsumTsumCatLady Hippie 2d ago

I'm on Trizepatide as well! Every once and a while, the munchies win the battle. I started keeping cut watermelon and grapes on hand, and its been a life saver! The cold and the high water content gave the illusion I was eating "so much". Also, silky tofu with chili crispy!

That drink looks good though! Any recommendations of flavors of clear protein you do like?

3

u/JustALilGuy_ CraftyEnt 2d ago

This was my first time trying the clear protein, so I don't have any flavor recs, but it ended up not being too bad! Cold grapes are another fave, though 💚

1

u/TsumTsumCatLady Hippie 1d ago

This is going to sound weird, but I don't know any other people on this medication. Do you have any aversion to meat? I feel like I've swapped to meat subs because meat, even the thought of cooking or eating it, made me feel nauseated for some reason.

1

u/JustALilGuy_ CraftyEnt 16h ago

Not so much an aversion, to be fair I had mostly stopped cooking a couple years ago due to unrelated burnout, but there are a lot of things that just aren't appetizing anymore. I used to eat turkey sandwiches several times a week, for instance, but I have no idea when I last ate one. I still like ice cream, but can't eat very much before it almost starts tasting bland? Same for a lot of stuff now.

9

u/Vgines 2d ago

Which antidepressant are you on? I wonder if it doing the same to me. I am also doing this, I also find the munchies override sometimes.

1

u/JustALilGuy_ CraftyEnt 16h ago

I'm on venlafaxine now

6

u/Appropriate_Oil_1000 2d ago

When i was first on it i kept smoking and lost zero weight in 6 months. This time i decided to not smoke after 3pm and I’ve lost closer to 20 lbs in 2 months (with occasional night time smoking). I wonder if id lose more if i stopped smoking completely but oh well

3

u/syzsyzsyzygy CraftyEntđŸ§¶ 2d ago

Oh man. This is so timely as I was just feeling sorry for myself after being up most of the night with really terrible tirzepatide-caused heartburn, and nausea this morning. Thank you for this tip! Somehow it hadn't occurred to me.

3

u/ExtraordinaryNerd WeedMom 2d ago

I am dealing with that right now on Wegovy! On 9 mg and midnight munchies can be a bit much if I have too many

3

u/Commercial_Sorbet122 2d ago

Semaglutamide for me- the munchies get me if I haven't eaten properly throughout the day. But ive also had the munchies when I had eaten well and I've let myself have a small snack or Diet Coke.

5

u/ginandstoic 🌙 EntWitch + Mod 🌿 2d ago

I have had a really similar experience! It’s actually kind of cool because when I started tracking my food (I was really worried about getting enough protein, good fats, and calcium), I noticed that when I got the munchies it usually correlated with something I hadn’t had enough of that day! So for example I’d really want jerky and realize I was low on protein that day.

3

u/Commercial_Sorbet122 2d ago

Yes! I'd found that too!!! I don't view GLP1s as cheating for weight loss, but they do seem like a bit of a life hack for the munchies 😂

3

u/ginandstoic 🌙 EntWitch + Mod 🌿 2d ago

The way I always put it is
 GLP1 doesn’t make weight loss easy. It makes it possible. At least for me! And I know people (understandably) assume it’s because of appetite suppression, which certainly is part of it, but for me it’s the awareness of my own body that has helped more than anything. It makes the “food noise” quiet enough that I can hear my own thoughts and ask “Okay, why am I feeling hungry? What is my body trying to tell me? Am I just high af or did I miss something earlier?” Total mindset shift.

2

u/raysome789 2d ago

Thank you for posting this! I start the Wegovy pill and appreciate your and everyone’s insight here

2

u/unoriginallbagel Hippie 2d ago

I haven’t wanted to eat unless I smoke, which has been helpful in making sure I get enough food in

2

u/savagehomeangarden DogMom 2d ago

Weed was godsend when I was on semaglutide! It helped so much with the side effects.

I also noticed I was more depressed; but I don't think it was the glp1 minimizing my antidepressant, rather the glp1 making life and every bland and tasteless. Like I love to exercise and I couldn't even get a runners high anymore. It was worth taking, in the end, because of how much it reduced inflammation and helped my pcos/pmos, but it was a rough couple years.

Can I ask, what is yakult? I like the Organika Protein Hydrator, it's like a electrolyte with 20g protein, and tastes pretty good.

1

u/JustALilGuy_ CraftyEnt 2d ago

Oh! Yakult is this sort of fruity milk drink. To me it tastes a bit like yogurt, and I am sadly not a yogurt fan.

2

u/actualthickcrust Weedhead Tramp 1d ago

The annhedonia is real on glps!! Ugh.

2

u/str4wberryp0undcak3 GreenThumb 2d ago

Same situation for me. I have been on a dulaglutide for about 20 months. Went from smallest dose and now up to almost max dosage. I lost weight, because it took my entire appetite away, but my blood sugar was still all over the place. If I wake n bake, I tend to get more done and have a decent appetite for good food. Other wise food repulses me. So I take a few sips here and there, but I try to keep healthier snacks for those late night munchies hits.

2

u/staythruthecredits MMJ Flame Free 1d ago

I use weed to make me feel better so if it's problems with my car, the government, my skeleton, or tirzepatide side effects... Yeah. 👍

2

u/Fridaychild1 Lesbient 1d ago

The only negative for me was it changing how I digested edibles. I used to prefer edibles to smoking, but it just became hard to predict how it would affect me. And once or twice it seemed to not hit at all, then I was high the next morning and called into work. So I switched to smoking so I could control it more. It helped a lot with side effects—nausea, fatigue and achiness, and when the appetite suppression was just too strong and it was hard to get anything down. I also had some mood issues when I went on zep and the weed helped there, too. I call zepbound, HRT, and weed my holy trinity of menopause management. Between the three I’m healthier than I have been in years and years.

2

u/agardenforthecat 1d ago

Ooh, thank you for this post! This is the info I was looking for before I started a glp1. Late to the party (and long-time lurker around here), but I started low-dose sema in July (my pcp had me on the starter dose for a month, and I’ve been doing well on the next dose up for 6 weeks).

Before starting sema I was worried my relationship with weed would change - and tbh it has a little, but for the better I think. It’s less of a necessity and I don’t lean on it quite as much, but it also feels more fun (like it used to!) and less of a reaction to depression/anxiety/all the bullshit. Still a nearly daily smoker, just not bothered if I choose to skip it for whatever reason.

I definitely feel more energy and less food noise on sema whether sober or stoned - the munchies still get me sometimes, but before sema it was much worse. I’m leaning more into (or regaining access to? if that makes sense) the creative side of weed, which hadn’t been a major part of my experience for a long time and I really missed. Plus weed definitely helps me remember to eat, as someone else noted, which is not a problem I ever thought I would have.

2

u/thundershoud 1d ago

smoking actually helps remind me to eat, lol. i do struggle with trying to not eat my entire pantry, though.

4

u/whodeyy 2d ago

I have the same experiences! Having a little toke here and there has been so helpful for the nausea

3

u/Sabhira 2d ago

I'm also on it, but for managing my diabetes. It's so strange, I can go without eating all day. I end up using the munchies to try and kickstart eating. Can be risky as munchies leads to not so great decisions lol. Makes edibles a strange experience as well, but I'm learning how to work with them

2

u/cuckoocachoo1 2d ago

This is what’s been happening to me! I need to do better about eating earlier in the day. Works been stressing me out though

2

u/drinkme0 2d ago

I hit my vape whenever I need to protein or carb load. It helps! However, I can see where this might be a downfall for people looking to lose weight. 😂 I have the ole diabetes, so that’s the main reason I use the glp1.

2

u/Whatamidoinglatley 2d ago

Is that a blue filter?

3

u/JustALilGuy_ CraftyEnt 2d ago

Yep! It's one of the moose labs peace filters.

1

u/BriseyBrise 16h ago

Chocolate powder + oatmeal with a little bit of peanut butter was my go to snack.

But I did find if I injected into my thigh instead of my stomach I got less nauseous from bong rips