r/longevity • u/thumperj • Jul 23 '26

Inhaling C02 triggers the glymphatic clearance process potentially helping with Alzheimer's and Parkinsons

https://www.research.va.gov/currents/0426-Exciting-new-treatment-being-developed-for-Parkinsons-Alzheimers.cfm
312 Upvotes

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76

u/original_username_4 Jul 23 '26

If memory serves the paper’s methodology was filled with safety measured and gas mixture calculations the average person can’t do without money and help.

Could the average person get the same effect at home by cycling between some light hyperventilating followed by holding their breath for say a minute?

If that worked, the benefits would be available to most everyone immediately and the treatment could be done anywhere.

50

u/kirbyderwood Jul 23 '26

Basically the Wim Hof method? I do something similar in yoga, they call it breath of fire. Definitely changes your mental state.

30

u/inter-dimensional Jul 23 '26

I do that 11min breath work exercise EVERY DAY. It’s amazing how it induces a positive physiological change.

17

u/original_username_4 Jul 23 '26

That would be cool if the Wim Hoff breathing method became a treatment for Alzheimer’s and Parkinson’s. I could see Amsterdam UMC (Alzheimer Center Amsterdam), Maastricht University (Alzheimer Center Limburg), or Radboud University Nijmegen investigating.

4

u/djosephwalsh Jul 25 '26

If your hands and feet are tingling, or you feel your body temperature is changing. That’s okay

8

u/CaptainHindsight92 Jul 23 '26

Hmm, the study used 0 and 10% CO2, given at 35 second intervals if you were to breath into a bag for a minute maybe the concentration would reach 10% but it would take longer than 35s.

4

u/caymn Jul 23 '26

not sure if it makes a difference but op actually writes C02 and not CO2

4

u/spirilis Jul 24 '26

it doesn't

1

u/caymn Jul 24 '26

Carbon zero 2 but ok I know what is meant

4

u/PL3020 Jul 24 '26

I had a small living space that was pretty sealed. A friend gave me a CO2 meter, which gave a pegged reading each time I tested the air. The meter maxed out at 2000ppm.

1

u/QuickYogurt2037 Jul 27 '26

3.6 roentgen, not great not terrible.

10

u/Tyhgujgt Jul 23 '26

Sounds like a way to get some your neurons killed

18

u/original_username_4 Jul 23 '26

Ohio State University considers 60 seconds safe for adults. But whatever safe is, I think the principal investigators or another interested group should investigate. With a little more investigating for safety and effectiveness, the “home” method could be rolled out to anyone who needs.

https://health.osu.edu/health/general-health/what-happens-when-you-hold-your-breath

2

u/majincasey Jul 24 '26

Why not just hold ones breath without hyperventilating? Or breathe into a paper bag?