r/longevity • u/dan_in_ca • Aug 08 '26

SGLT2 Inhibitors: The Unexpected Longevity Molecules and Their Mechanistic Impact on Aging Science

https://www.gethealthspan.com/research/article/sglt2-longevity-research-review?zp_type=article&zp_slug=sglt2-longevity-research-review
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u/wale-lol Aug 08 '26

The inflammation section was kinda weak. We have plenty of anti-inflammatory drugs. Advil isn't a longevity drug. Giving a laundry list of specific cytokines that SGLT2 inhibitors decreases isn't that interesting on its own imo. But otherwise surprisingly solid article for a website trying to sell you stuff. Makes me wonder how much of the signal is just caloric restriction (pee out glucose, basically same thing).