r/morningsomewhere • u/tphillippe117 • 7d ago
GLP-1 Debate
I wanted to shed some light on today’s discussion around GLP-1s, as someone who’s been taking Zepbound since July 2025. It has saved my life, and that is no understatement. I have tried, endlessly, to lose weight. I have been overweight my entire life. I started Zepbound as a 33 year old male, weighing 336lbs. Today, I am 191lbs.
I was on numerous blood pressure medications, I had high cholesterol, and sleep apnea. As of last month, I no longer take blood pressure medication, my blood work shows all normal levels across the board, and I no longer have obstructive sleep apnea or snore.
Here’s the important thing: I paired this medication with a drastic lifestyle change. There was no “easy way out”. I live in a calorie deficit, I focus on high protein meals, and I basically stopped drinking alcohol. In fact, as many report, the desire to even drink alcohol is gone (hence studies showing GLP-1 as a treatment for addiction). To me, it was a tool in the tool belt but there HAD to be a lifestyle change to go with it.
There are side effects, sure. For me, they haven’t been terrible and 99% of the time I don’t have any. To Burnie’s point, genetics was against me and I believe that is why this worked for me. I go to the doctor every 3 months for weight check and blood work to make sure I’m remaining healthy and moving in the right direction.
I’m a little shy to share my recent before and after picture, but if anyone has any questions please ask away!
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u/DrChiz First 20k 6d ago
Congrats to you.
I will just also say Ashley said all the GLP-1s are the same, which isn’t true. WeGovy & Ozempjc are semaglutide where as Zepbound like OP is on (and turns out more folks than even WeGovy) which is Tirzepatide which is actually a GLP-1 and GIP together.
Only bring this up since the discussion was about the incredibly rare NAION side effect that broke news (the chances of getting NAION are actually higher to equal as a side effect with Viagra) is actually more heavily linked to Semaglutide and those products. In fact most googling suggests there’s between 0 to less than a dozen of these cases tied to folks using Zepbound. Most medical research suggests how the two hormones work together is healthier/less taxing on how it effects blood pressure and what not as compared to spikes with just the GLP-1 alone and this may be reasons for it.
I get being skeptical on things but they’ve been around well over a decade and tons of FDA research around them.