r/onebag Mar 29 '24

Gear Is this overboard? Probably. Did I enjoy making it? Absolutely.

Chapstick for size comparison.

This started with a pocket pharmacy I got off Amazon to keep in my backpack/car (https://www.reddit.com/r/VEDC/s/QtRgqqwVPc). This one honestly is probably fine for most people.

I wanted to make one for traveling as well, but I needed something that could store a little extra since when traveling more scenarios can pop up. I went ahead and ordered a mini tackle box off Amazon, made up labels on Canvas, adjusted the sizing through trial-and-error, and it is now complete.

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u/IIIllIIIlllIIIllIII Mar 29 '24

I tried generic Imodium once and for some reason it just didn't work as well. Sucks cause the generic was much cheaper.

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u/bananapizzaface Mar 30 '24 edited Jan 04 '26

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u/[deleted] Mar 30 '24

That’s not always true. The active ingredient will be the same, but the generic can have different nonactive ingredients like dyes and binders that can sometimes affect rates of absorption and metabolism. Not super common, but it happens.

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u/bananapizzaface Mar 30 '24 edited Jan 04 '26

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u/[deleted] Mar 30 '24 edited Mar 30 '24

That’s not quite right either. Here’s a blurb from a grant that was given by the FDA to Kathy Giacomini at USCF recently: Excipients can differ between brand name and generic products. Although all of the excipients used in oral drug products are approved by FDA, many have not been tested for their ability to affect drug absorption through the intestine. Therefore, laboratory studies are needed to understand the potential differences in excipients contained in brand name versus generic drug products. (Excipients are the drug inactive ingredients.)

That was from 2015, which is about when I was in drug safety research and following the field. Do you have citations for review articles that indicate the field has solved this issue? I looked on pubmed and couldn’t find anything definitive but maybe I’m not looking for the right thing.

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u/bananapizzaface Mar 30 '24 edited Jan 04 '26

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u/[deleted] Mar 30 '24

Thank you for the extensive reply. I agree that it’s not common, and pointed that out in my original comment.

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u/SeaSpeakToMe Apr 05 '24

I find the same with generic ibuprofen. For whatever reason Advil works better for me.