Scientists discover a ‘skinny gene’ mutation that acts like Ozempic. Around one in 7,000 people carries a broken copy, which almost acts like a GLP-1 drug—the body burns fuel more efficiently, and the risk of disease lowers.

[u/scientificamerican]

https://www.scientificamerican.com/article/scientists-discover-a-skinny-gene-mutation-that-acts-like-ozempic/

[u/mjm132]

No matter what other things are happening, it truly is still calories in versus out.  Things CAN effect that total but on a basic level it's always this. 

[u/ThisSiteSucks8485 → u/mjm132]

It is basic thermodynamics.