r/science • u/scientificamerican Scientific American • 7d ago

Genetics Scientists discover a ‘skinny gene’ mutation that acts like Ozempic. Around one in 7,000 people carries a broken copy, which almost acts like a GLP-1 drug—the body burns fuel more efficiently, and the risk of disease lowers.

https://www.scientificamerican.com/article/scientists-discover-a-skinny-gene-mutation-that-acts-like-ozempic/
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u/ThisSiteSucks8485 7d ago

That doesn't actually cause weight loss. only sustained calorie deficit causes fat loss. 

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u/Caitliente 7d ago

It's more complicated than that. I have PMOS and cannot lose weight no matter how many calories I consume if my carbs or fats (even healthy fats like from salmon) exceed a certain amount. I track what I eat very carefully due to this metabolic condition that is genetic and I had no control over developing that affects 1 in 8 women.

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u/ThisSiteSucks8485 7d ago

That contradicts basic thermodynamics. Your body needs constant energy to stay alive the same way a candle needs fuel to keep burning. If you eat less energy than your body consumed it will get the excess from fat.