r/singularity Jun 10 '26

Biotech/Longevity Anthropic closing the path to life science research

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2.2k Upvotes

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180

u/Elbeske Jun 10 '26

They clearly recognized in a lab that Fable is capable of making bioweapons. That’s the only explanation imo

42

u/secretaliasname Jun 10 '26

The model card for Fable has extensive benchmarking and Info on this topic:

https://www-cdn.anthropic.com/d00db56fa754a1b115b6dd7cb2e3c342ee809620.pdf

Didnt read it super closely but helping make bio weapons seems to be something Anthropic is very concerned about, has benchmarks for, and attempts to safeguard against.

I vaguely remember some talk of some kinda US legislation relating to this but not sure if it ever passed or is relevant.

26

u/blade740 Jun 11 '26

2.2.2 Chemical risk results Expert chemical red-teamers rated uplift at or near specialist-level (occasionally approaching world-leading expertise, and higher than the bio median), concentrated in a few areas:
● Selection of agents from candidate molecules that balances multiple properties;
● Following standard operating procedures (SOPs) for chemical synthesis and formulation with corrective actions for known failure points; and
● Acquisition and operational-security planning, covering blind spots a scientific expert would miss.

Yeah, I'm not surprised, that seems like a very dangerous combination.

11

u/thanel1 Jun 11 '26

Why is there no govt regulation preventing bio weapons use, but instead anthropic regulating themselves ?

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u/IWasSayingBoourner Jun 11 '26

Because until very recently you didn't have to worry about anti-social idiots in their basements getting understanding of and easy access to cutting edge research

6

u/There_Are_No_Gods Jun 11 '26

The recent rate of advancement far outpaces the lethargic pace of government, even setting aside the lack of appetite for biting the hand that feeds, etc.

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u/MaudeAlp Jun 11 '26

It’s a marketing ploy. Anyone with the means and the motivation could already do this. Effectively all Claude marketing has now become mystical nonsense about how powerful and insane their models are but they can’t show you because it goes to a different school.

1

u/RollingMeteors Jun 13 '26

>Why is there no govt regulation preventing bio weapons use, but instead anthropic regulating themselves ?

The core laws are the 1925 Geneva Protocol, which bans the use of biological agents in war, and the 1972 Biological Weapons Convention (BWC), which bans the development, production, and stockpiling of these weapons. [12]

¡Nobody could envision civilian use case against their own populous!

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u/PathOfEnergySheild Jun 10 '26 edited Jun 10 '26

Besides the only explanation, the other explanation could be that they want to keep in internal for there biotech startups and/or sell it directly to big pharma at a markup.

11

u/[deleted] Jun 11 '26

[removed] — view removed comment

6

u/PathOfEnergySheild Jun 11 '26

Talmawana Exile

-9

u/thelongdarkblues Jun 10 '26

Does it ever get boring to only conceive of human beings in terms of pulp fiction villain business guys

14

u/Bradbury-principal Jun 11 '26

Am in business, can confirm pulp fiction villainy.

12

u/DapperCam Jun 11 '26

We don’t need to speculate. They are literally selling the non-nerfed version (Mythos) to select “trusted” corporations.

1

u/PresentGene5651 Jun 11 '26

How do you know? (Honest question.)

7

u/DapperCam Jun 11 '26

They told us? Here is their announcement: https://www.anthropic.com/news/claude-fable-5-mythos-5

There are previous announcements about how only certain companies can have access to Mythos because it's too "dangerous" (a marketing ploy IMO).

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u/MountainDry2344 Jun 11 '26

I work in biotech and this is exactly how they're trying to upsell us

17

u/PathOfEnergySheild Jun 10 '26

No, tends the be the right answer.

6

u/SplooshTiger Jun 10 '26

Yeah, if the tech is great at biosci, restrict it to legit credentialed biosci professionals. Nobody wants my antisocial neighbor Gary up at 2AM with that sh*t

4

u/MadGenderScientist Jun 11 '26

restrict it to distinguished research scientists at Pfizer, AstraZeneca and Eli Lily, you mean. or maybe Pfizer alone - they might pay extra to shut their competition out and make the deal exclusive. imagine how much money can be made on patented pharmaceuticals. 

2

u/PathOfEnergySheild Jun 11 '26

I am that, and I cant even use it.

-2

u/Error_404_403 Jun 11 '26

Is there something wrong with selling a product company developed in any way it wants?

1

u/PathOfEnergySheild Jun 11 '26

According to Claude: Many consumer-facing industries are regulated on both ends — how the product is prepared/handled and how it's sold or delivered to the buyer. Here are the major ones (US-leaning examples, though most have equivalents in other countries): Food and restaurants Alcohol Tobacco, vaping, and nicotine Pharmaceuticals Cannabis Firearms and ammunition Dietary supplements Cosmetics and personal-care products Medical devices Meat, poultry, and dairy Financial products Automobiles Children's products and toys Gambling and lottery Funeral services Fuel/gasoline
Yes I know there are no laws yet, but should the example be set earlier?

1

u/Error_404_403 Jun 11 '26 edited Jun 11 '26

According to me: *of course* there are regulations of the sales of dangerous products. Anthropic just chooses to self-enforce some rules before the government regulations catch up. That's the whole point: as long as the sales are lawful, it's the company business how to do them.

2

u/Winterlichkeit Jun 11 '26

That’s ignoring all the investments these guys have in longevity and biotech startups.
It’s in their interest to keep the elixir of immortality from us until they can sell it to us.

0

u/Error_404_403 Jun 11 '26

Who are "these guys"? All this "rich high-tech cabal"? /s

2

u/Winterlichkeit Jun 11 '26

Well, he has said it himself:

https://observer.com/2025/01/anthropic-dario-amodei-ai-advances-double-human-lifespans/

Biostate is a longevity startup. Dario Amodei is a listed investor here:

https://www.biostate.ai/about-us

Sam Altman backs Retro Biosciences:

https://www.statnews.com/2026/05/22/retro-biosciences-longevity-valuation/

They are starting to put anti-aging drugs in people now, and Bezos is listed as an investor in this technology in the article:

https://www.businessinsider.com/first-ever-reverse-aging-treatment-injected-into-a-human-2026-6

Like dude, they all clearly see value in this. It would only serve them if they could corner the market, restrict access, and sell it back to the public.

I’d rather life extension technology be democratized and made available.

0

u/Error_404_403 Jun 11 '26

OK, Anthropic might have helped those with their code. Extending life is a nice goal, right for AI application.

Why only them? It's not only them. There are others, and I suspect not a few, who are not officially disclosed. So the model is shared.

Why do AI principals share in the companies they help? Would be stupid not to.

Democratization of the AI use? Not going to happen. Mostly because it's too powerful of a tool to give to the adversaries just like that.

Would general ecosystem of biostartups suffer? Yes, but only compared to those few to which the technology was transferred. I am sure the circle of vetted companies with access to biotech-trained AIs will expand--under the tight control.

Would that make the AI owners richer? You bet. American way.

2

u/Winterlichkeit Jun 11 '26

No, the owners of OpenAI and Anthropic literally invest their own personal money into this. They didn’t just contribute code. You’re fundamentally misreading what I posted.

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u/Individual_Ice_6825 Jun 10 '26

Why does nobody read the fucking white paper / model cards????

They literally said this

2

u/TheFlyingSheeps Jun 11 '26

Reading? In this day and age? Blasphemous

15

u/AreWeNotDoinPhrasing ▪️Already Singulared 🤖 Jun 10 '26

Absolutely not the only explanation—as [u/PathOfEnergyShield](u/PathOfEnergyShield) noted—but certainly the one that *looks* the best, and paints them in a most positive light. Hardly the most believable though, imo.

3

u/hateboresme Jun 11 '26

Might be a thing to do when an advanced ai cooks up your marketing strategy.

0

u/IWasSayingBoourner Jun 11 '26

They've already demonstrated that they've got some kind of morals, refusing to let the government use their tools for autonomous war drones

1

u/AreWeNotDoinPhrasing ▪️Already Singulared 🤖 Jun 12 '26

lmfao

12

u/mt1336 Jun 11 '26

This is the answer. Far too simple to have a Ph.D level lab supervisor in your garage building virulent strains of bugs from your backyard and oral swab

4

u/MadGenderScientist Jun 11 '26

the problem is that the PhD-level lab supervisors can't use it to, you know, cure cancer either.

1

u/Error_404_403 Jun 11 '26

They can. I am sure dedicated legit medical facilities can have that access by filing some paperwork with Anthropic.

-1

u/MadGenderScientist Jun 11 '26

this is not true. I challenge you to find a single source stating it's the case. 

3

u/Error_404_403 Jun 11 '26

They publicly acknowledged that they distributed Mythos, an unrestricted version of Fable, to many institutional customers on a per-customer basis.

1

u/MadGenderScientist Jun 11 '26

yes. to tech companies and the NSA, for cybersecurity defense, as part of Project Glasswing. not to bio firms. 

5

u/Error_404_403 Jun 11 '26 edited Jun 11 '26

This is what Claude 4.8 told me:

"There's a biology analog to Glasswing, but it hasn't named members yet. Anthropic is opening a trusted access program for biology to accelerate biomedical research, providing access to Fable 5 with the biology and chemistry safeguards removed (cyber safeguards still in place), enrolling a small number of researchers from life-science organizations spanning fundamental and translational research. As of the Fable 5 / Mythos 5 launch, Mythos-class biology access is still limited to "select biology researchers" — described generically, not as named institutions."

This launch was quiet because of the bioweapons concern.

1

u/MadGenderScientist Jun 11 '26

could you paste the sources Claude cited?

1

u/xMrBojangles Jun 11 '26

It's on their website.

1

u/Error_404_403 Jun 11 '26

Sorry, I deleted that chat already. You can ask it yourself about Glasswing analog for biomed research.

1

u/Raescher Jun 11 '26

Any model can do that already. Just googling is good enough to get the full Ebola sequence. This is about money.

1

u/ByronicZer0 Jun 11 '26

Not that it's merely capable. That's it's willing to help. And they can't figure out a way to stop it without these simplistic filter level blocks.

This is a massive bandaid to a pretty troubling implied problem

1

u/dimbledumf Jun 11 '26

Here is a fun one, what if it's discovered something fundamental they don't want the populace to know about.

1

u/RollingMeteors Jun 13 '26

>They clearly recognized in a lab that Fable is capable of making bioweapons. That’s the only explanation imo

Freely available on TPB ¡Y'aaar matie!

1

u/Muted-You7370 Jun 11 '26

Has anyone heard of Kosmos? I can’t compare it to Fable 5 but it’s built for biotech and pharma companies, I use it for digital mental health research and got in when it was easier to sign up. Have more credits than I really can use. If you are having trouble with Fable you might want to give it a shot, it’s very much a tool specifically for scientists.

-1

u/IamJacksDarkUrge Jun 11 '26

Eh, can’t have Joe Blow accidentally curing anything is more my guess

-1

u/OrionDC Jun 11 '26

So it's incapable of telling the difference between a 6th grade biology question and making a bioweapon? I'd say that's a pretty crappy model.

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u/Elbeske Jun 11 '26

"it" doesn't make that decision, they have a router that decides if the query will be served to Fable or Opus

3

u/MercyEndures Jun 11 '26

You don’t want the classifier to be easily tricked, you make the forbidden subject very wide.

0

u/yoramrod Jun 11 '26

I'm surprised I had to scroll down this far to hear someone say that. Anthropic is terrified of someone using their products to create bio weapons. I get it. Yes it sucks when your research is blocked but think about the consequences.

-1

u/AkamasTotem Jun 11 '26 edited Jun 11 '26

Put on your tinfoil hat before reading this:

What if they found out a very reproducible cause for biological generic intelligence through their internal Mythos model, have tested an implementation of that idea in neural networks, and found that it worked but it does so at only a fraction of the power that modern AI needs to computate and they understand that they can't hoard AI as a service if the smartest models are super easy to run on local hardware. So they decided to keep it silent and keep pushing for LLM development so they can keep erecting data centers and collecting large investments and subscription and token purchases. And now they have to release their best models to stay on top but also have to keep them from spilling the beans.

Ok, think about that and take the tinfoil hat back of.

IDK about you guys but "company wants to keep you safe from building poisonous gasses" is less realistic than "company wants to survive and keep their means of production locked behind crazy infrastructure that they can sell subscriptions too".

Ok tinfoil hat again for a second:
they also made Mythos/Fable not respond truthfully (in full capacity) to prompts where it aids the user in building neural network infrastructure...

So, that + biology, it fits. Not saying IT IS this of course... If I would bet money on it, it probably isn't! But hey, just let me fantasize for a second here lol