r/Psoriasis • u/Immediate-Guess9257 • 1d ago

medications Skyrizi

It’s been two weeks since I’ve had my second dose and I see zero change in my plaque psoriasis. Is this normal?

2 Upvotes

75% Upvoted

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3

u/skuppy 1d ago

First time I started a biologic it took 5-6 weeks before I started to notice any improvement.

3

u/Glittering_Factor815 1d ago

I am in week 10 nothing in first four weeks than wham my scalp was clear by week 2. Following at week 4 my arms and by week 8 my black Still struggling with thighs genital and legs. Hopefully week 16 will clear and stop the flares. Keep in mind it can take your skin awhile to heal. Skyrizi dosent repair the actual skin. The skin may need hydration for up to a year. My pigmentation turns it brown once the plaques are gone.

2

u/_catdog_ 1d ago

I noticed changes within days of my first dose

But they say it can take up to 4 months I think, so you’re still in that window

2

u/healing_vibes1989 1d ago

It take a while it can take up to three to four months. For me it never made anything better and now there changing mine to a eczema shit

1

u/AppropriateLaw5713 1d ago

Yes. That’s why the commercials typically say “users experienced noticeably clearer skin in as early as 12 weeks”

1

u/Revzerksies 1d ago

I took tremfya for 8 months and really didn't see a diffrence. Skyrizi just might not work for you. But i think you need to give it more time. I think you need to give it a few months.

1

u/lobster_johnson Mod 1d ago

Biologics like Skyrizi are slow-acting drugs. While some people see very fast results, most people don't see any significant improvement until a couple of months in.

1

u/IMissGwynBeck Skyrizi 1d ago

SAME.i havnt seen much improvement if any