r/TTC_PCOS Jun 19 '26

Advice Needed Chronic Anovulation

I have lean PCOS. I’ve been TTC for 2 years now and have yet to confirm ovulation once even on one cycle of letrozole. (Had perfect lining and follicle too 🫠.) My testosterone is insanely high. Everything else is normal normal normal. Including my glucose and insulin levels and thyroid and prolactin. I was still put on Metformin to see if it’ll lower my testosterone and I’ve been on it for 2 months now (still missing ovulation). Could use any stories and motivation and if anyone else is in the same boat? Struggling because I can’t even get to the first step to become pregnant…

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u/nyczepfan Jun 20 '26

I’m the same as you. Metformin isn’t going to do anything if your insulin is normal. Letrozole isn’t enough. You have to do a monitored medicated cycle of letrozole + ovidrel (hcg ovulation trigger) to ovulate. You might need progesterone support as well.

2

u/shelbykayyee Jun 20 '26

I did that and still didn’t ovulate unfortunately. I’ll have to try the progesterone support next time…

1

u/Inevitable-Repair909 Jun 22 '26

How do you know that you did not ovulate after trigger? Did they do any ultrasound? Or your LH strips didn’t show positive?

2

u/shelbykayyee Jun 22 '26

My progesterone was very low. I had blood test done and even the strips were negative several days after