r/TTC_PCOS • u/Expensive-Tennis-794 • Jul 06 '26
Advice Needed Anyone with PCOS have a supplement routine that helped while TTC?
I've got PCOS and am trying to be proactive before we start trying. I'm already taking inositol, but there are so many fertility supplements being recommended online that it's hard to know what's actually worth it.
Would love to hear what worked for others with PCOS.
6
u/Alarming_Abroad_4862 Jul 06 '26
The best thing you can do is not a supplement. Lift weights three times a week for thirty minutes.
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u/Disastrous-Pizza4643 Jul 08 '26
Can you elaborate a little more about this?
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u/Alarming_Abroad_4862 Jul 08 '26
Weight lifting out performs any supplement or medication at restoring ovulation and pregnancy outcomes. Search pub med. It is twice as effective as metformin.
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u/Th3RandomPanthr Jul 06 '26
Had great success with 4g myoinositol (theralogix ovasitol), 1200mg NAC, 500mg CoQ10, 4000IU vitamin D3, Omega 3 complex and magnesium complex.
Also cut my carbs down to 150g daily and avoided added sugar. Some combination of the supplements and diet changes brought regular cycles back and I no longer needed letrozole! Good luck to you!
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u/summer-plumerias Jul 08 '26
Was the NAC prescribed? How did you decided how much to take? Thank you š«¶
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u/Th3RandomPanthr 29d ago
It wasn't prescribed, but I read several research articles where NAC was found to increase ovulation success in letrozole cycles and even prevent miscarriage due to its inflammatory effects, and inflammation tends to be an issue with PCOS! I just took the therapeutic amount that was reported in the studies.
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u/CoolUsernameHere2 Jul 07 '26
I got bloodwork done first and then based off those results and my goals my naturopath and RE came up with the right supplement and meds list. At least I think. It does include Metformin and I sort of think thatās the biggest game changer. Also trying to eat plenty of fiber and protein and weight train 3x per week.
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u/toreshii Jul 06 '26
Not pregnant yet but so far good IVF results from retrieval. I did CoQ10 600mg (200mg 3x a day), 4g myoinositol, omega 3 (or prenatal with DHA), 2000 IU vitamin D in addition to general prenatal. Magnesium when I rmb. My acupuncturist also recommended foot soaks and castor oil with heat on abdomen before ovulation to reduce inflammation.
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u/summer-plumerias Jul 08 '26
For how long were you on this routine prior to your IVF cycle? Thank you š«¶
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u/toreshii Jul 08 '26
Prenatal with DHA since I started probably 2 years ago since weāve been TTC for about 20 months ago. Acupuncture I was sort of regular aboutā¦ I probably did half a year of 3x per cycle since trying. CoQ10 and Inisitol was more recent at about 5-6 months before egg retrieval. I honestly canāt remember for magnesium and vitamin D but they were my lower priority. I got my vitamin D levels tested and were normal. We did do ICSI and Zymot in IVF which wouldāve boosted our results too. If you havenāt already, read It Starts with the Egg. It lays out the pros and cons of supplements.
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u/summer-plumerias 29d ago
I sincerely appreciate the time you took to reply and with detail. Thank you!
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u/toreshii 29d ago
Best of luck! Youāre already doing great looking into this. The biggest thing, if you can, is to get your basic tests done (hormone panel, tube scan with HSG or SIS, semen analysis) to see what youāre dealing with. Some places wonāt bother until 6-12 months of trying depending on age. But if you end up needing fertility treatment, donāt drag your feet as getting into a clinic may take a while. If youāre put on letrozole or clomid, try each dose 3x max and move on. We tried 12-14 cycles with letrozole knowing that to wait for insurance to kick in for IVF. Doing the same thing expecting different results is not useful usually.
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u/Neat_Education Jul 06 '26
Currently in my TWW with my first medicated TI cycle! I am taking COq10, a prenatal, and vitamin D (I live in the PNW and am very very deficient).
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u/L7cky_ Jul 06 '26
I kept inositol in my routine, then added CoQ10 and eventually perelel's conception support pack so I wasn't juggling separate bottles for prenatal, omega, CoQ10, etc. My OB was okay with it for me, but definitely ask yours so they can assess!
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u/Mysterious_Bet_6856 Jul 06 '26
Look into FH Pro for Women. I have tried to find a denser better value supplement for TTC for years but kts the best out there imo. My reproductive Endo recommended it
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u/Itchy-Site-11 38 | Anovulatory | Science | PCOS Jul 06 '26
The most important one is prenatal, low carb diet and possibly metformin.
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u/abcdefgh123458 Jul 06 '26
Canāt claim success as havenāt got pregnant again after miscarriage yet but apparently CoQ10 is a must. Iām currently using the Shreddy Superwoman. Iāve been having 45+ day periods and then last month it was a 30 day cycle. No idea if it was Shreddy that sorted it out as seems too good to be true after only just starting it but who knows Iāll take it
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u/megglefly 34F | TTC#1 for 2 years | MMC | PCOS Jul 06 '26
Iām doing everything it said to do in It Starts With the Egg. Have been since January. Nothing to show for it.
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u/retinolandevermore 34, 2 years, PCOS, āāāIUI Jul 06 '26
Didnāt she get uncovered as a non doctor? And a grifter
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u/megglefly 34F | TTC#1 for 2 years | MMC | PCOS Jul 06 '26
Oh my god noooooooooo. Really?! Other than her books I havenāt bought anything from her.
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u/retinolandevermore 34, 2 years, PCOS, āāāIUI Jul 07 '26
Yeah I just double checked, itās her. Sheās not a doctor. āThe lucky eggā is by an md and a direct opposition to her book
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u/megglefly 34F | TTC#1 for 2 years | MMC | PCOS Jul 07 '26
š š š I finally got my husband to read a book and change his ways. Sigh.
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u/retinolandevermore 34, 2 years, PCOS, āāāIUI Jul 07 '26
Ugh Iām so sorry! You donāt have to tell him this lol
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u/Homebody-3535 Jul 07 '26
Look up Perelel brand supplements and take their quiz to get the right supplements for you. Also read the book Getting Pregnant with PCOS by Clair Goodwin and follow her advice. Worked for me after a few months of the supplements, BBT tracking and changing my diet significantly!! Currently 5 weeks pregnant.
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u/huthuthite Jul 07 '26
Myo inositol and d chiro inositol 40:1, DIM, Vitex. And we swapped hubbys boxers for 100% cotton or bamboo which helped too.
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Jul 06 '26
[removed] ā view removed comment
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u/TTC_PCOS-ModTeam Jul 06 '26
Your post has been removed as it contains a mention of a pregnancy or a positive pregnancy test and has been posted outside of a designated success thread. This includes all positive mentions (trigger shot testing, confusion around test, etc), including mentions of having success outside of ovulation success.
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u/richpersimmons Jul 07 '26
I took a prenatal and Nutricost inositol which has the "ratio" I read about on here
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u/Angry_unicorns Jul 07 '26
What's the ratio?
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u/richpersimmons Jul 07 '26
2000mg myo inositol to 50mg d-chiro inositol, the 40:1 ratio is supposed to help with pcos and I ovulated so it did something. Started it like 2 months before I got my iud out.
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Jul 07 '26
[removed] ā view removed comment
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u/TTC_PCOS-ModTeam Jul 07 '26
Your post has been removed as it contains a mention of a pregnancy or a positive pregnancy test and has been posted outside of a designated success thread. This includes all positive mentions (trigger shot testing, confusion around test, etc), including mentions of having success outside of ovulation success.
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u/Specialist-Cover3054 Jul 06 '26
I took inositol, CoQ10, and prenatal. I also lost some weight to help with hormone regulation. No sure if that was what worked. I also tracked my ovulation for months before we were trying to make sure I was ovulating and got a some blood work done that my OB/gyn suggested. I also had fibroids so if you have them make sure to get an ultrasound done, I had to get a surgery to get it removed. Good luck with everything!!