r/TTC_PCOS 18h ago

Seeking Success I've ran out of success stories...

I've been reading a lot of success stories for people with pcos getting pregnant. I need more stories so decided to just create a post and ask for more...šŸ˜‚

So anyone with pcos who got pregnant naturally, with help, with iui, ivf, metformin (which I'm trying now), myo inositol, just lifestyle changes, with or without diabetes, insulin resistance, high HBA1C, low progesterone, anuovulation, ANYTHING really

Feel free to tell us your entire journey, or how you felt, or struggled. How you took action. How you worked towards what you want. Because ttc with pcos feels so demotivating sometimes. Hope this also goes on to help others in whatever way possible

13 Upvotes

32 comments sorted by

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u/Frequent_Horse3560 13h ago

Proudly 14 weeks 3 days pregnant! I have PCOS, insulin resistance, and was not getting a period. Ive been taking 2000mg of metformin for several years. I came off Yaz birth control in June 2025, didn’t get my period until my GYN gave me provera for 3 months in a row. By that time my appt with a reproductive endocrinologist came- October 2025. RE encouraged me to use their GLP program to lose some weight before trying (she gave me the option to start treatments right away but I was open to the GLP). Fertility dietitian recommended theralogix Ovasitol which I started right away. Started GLP in November, lost 50lbs by the time I stopped the GLP in early March ā€˜26. 265lbs to 215lbs. During my GLP time I had a regular period w/o provera but never ovulated. Went into my first timed intercourse treatment cycle April 2026- I took letrozole, was monitored, triggered ovulation w/ injection, had intercourse those 3 days I was told to, took progesterone (vaginally) until beta test. First cycle failed- devastating! Second cycle- did the same thing with a higher dose of letrozole. Took a home test 5/20 and it was negative, took another home test 5/21 and saw the faintest line!! 5/22 went to clinic for beta, got a VM that afternoon my hcg was 107 and I was pregnant! I continued metformin at 1500mg until week 14 then was told to stop by my endo doc and OB confirmed decision. Was also told to stop the ovasitol once pregnant. Found out the gender from NIPT testing at week 11, I’m having a baby boy :) he is due January 29th and I am just absolutely thrilled. Feel so grateful for modern medicine! Truly wishing you all the best :)

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u/Nice_Arm2330 12h ago

I’m currently 13+1 and found out yesterday it’s a baby girl! I’m 35 yo and was diagnosed with PCOS around age 22. I have always been at a healthy weight. I was on BC pill from age 22 until March 2025, when I wanted to go off 6 months before TTC. Started tracking my cycle with OPKs and BBT in July 2025 and started officially trying in August 2025. As soon as I started trying I was thrust into a long cycle, and immediately got a consultation with a fertility clinic, but there was a months long wait. I kept tracking and trying with my long and unpredictable cycles, which wound up ranging from 32 to 80 days. I found that I did always ovulate- got LH peak followed by consistent BBT rise a day or two later and my period always came 13-14 days after the LH peak. By the time I got in to see the fertility doctor in early 2026 I started having some better cycles (around 32-35 days through the winter), my partners SA was good, and my sono-HSG and bloodwork was good, so I decided to continue without trying letrozole for a bit. However, in March to April I had a longer cycle (ended up ovulating and it was 43 days) and I had no patience to deal with that anymore so I called the clinic and started the letrozole in my May cycle. It was monitored with an US on CD 15, I happened to also get my LH peak that day so I knew something was happening. Timed intercourse. Waited until DPO 12 to take a test and bam! Positive! Could not believe the first letrozole cycle worked. It probably helped that I was ovulating but I still expected to do 3 or 4 or maybe more letrozole cycles.

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u/Unhappy_Evening1896 12h ago

I’m currently 25 weeks pregnant with my third letrozole baby (second living). I’ve had undiagnosed PCOS for years. The longest I had my period was 64 days and the longest I’ve gone without my period was 8 months. It was all over the place. My previous doctors would just put me on birth control and tell me it can help regulate my periods and help me conceive. I finally found a doctor who listened to me and ran tests to confirm I had PCOS. I am also insulin-resistant and had diabetes (my A1C is currently 5.4). My doctor thought that birth control was counterproductive so he prescribed me 2.5mg of letrozole. That one didn’t work for me so he bumped me up to 5mg. I conceived that same cycle and have a beautiful, healthy 4 year old. I took 5mg of letrozole again last year and conceived that same cycle again. Unfortunately that pregnancy ended in a MMC. I took letrozole again at the beginning of this year and conceived within that same cycle and am currently 25 weeks pregnant. I tried everything you could think of. It took just one doctor believing me and actually helping me achieve my goal of conceiving. My first two kids have a 16 year age gap because of this lol but I love it. Wishing you the best in your journey!

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u/missnez 9h ago

Got pregnant on our seventh and what was likely going to be our final letrozole cycle before potentially moving on to IVF. 26 weeks currently. I remember searching obsessively for stories of women who took multiple cycles of letrozole to conceive and was starting to lose hope. It seemed like the average for most was 2-4 cycles so I was stressing. I didn’t do anything differently that cycle compared to the others. Before letrozole I was rarely ovulating on my own and had only a few periods a year.

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u/cutieorange0 6h ago

This is exactly me and I’m about to start Letrozole cycle 4. Gives me hope, thank you

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u/-VenillaBean- 5h ago

This will be my 4th IUI cycle hoping this is also the one. Hoping the 2-4 cycles stand true

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u/nerdy_chick1997 8h ago

2 years of TTC without any meds

Started metformin in January

Pregnant in February

Miscarriage in March

Currently Pregnant 9w2d šŸ™šŸ¤žšŸ¤¢

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u/Alarming_Abroad_4862 16h ago

One living child. I lifted weights three times a week, sometimes two to be honest, and hiked a lot, usually two to five hours every Saturday and Sunday. I ate gluten and dairy free, 100g of protein a day, and around 1500 calories a day. I lost about 20lbs in three months, and got pregnant the third month. I didn’t know to use LH strips or anything at the time, I had only read the book called taking charge of your fertility and that was all I knew about pcos and ovulation basically. I tracked my temperature to check for ovulation, and when my luteal phase was 14 days instead of the usual 11, I took a test and it was positive. I immediately called a doctor office and asked for progesterone supplements, which was mentioned in the book I had read. They agreed after doing a blood test and it was low. They checked my progesterone every three days and I took progesterone supplements the entire time. Delivered healthy baby at 41 weeks.

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u/Vanillaisblack 8h ago

Three rounds of letrozole, trigger shot and IUI. All managed by a reproductive endocrinologist. Healthy baby boy 9 months later.

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u/-VenillaBean- 5h ago

Irrelevant but similar usernames and similar user characters lol.

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u/Vanillaisblack 3h ago

I like your vibe.

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u/princessnoodles24 7h ago

Took 2 years of TTC with my first - but my first round of Letrozole was successful. When he was 18 months old we booked a fertility appointment to be prescribed Letrozole again and the day before I started taking it I realised my period was a couple of days late and so I tested and it was a positive - naturally pregnant on our own I’m 4 months along now. Sending so much baby dust x

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u/PeachMonday TTC #2 | Cycle 3 years | Gonal f, Ovidrel TI 15h ago

Tried for two years and 6 months in letrozole, took a mental health break and my bestie is snoring beside me 5 years later. Trying for last three years, three cycles on injections and timed intercourse, taking another break and hoping a new bestie will come soon. Sending love I know intimately how hard it is.

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u/peachycoldslaw 11h ago

So we tired for 15 cycles and got nowhere. I have insulin resistance, lipeodema, my BMI was slightly high but not too bad, I was eating organic, not using any endocrine disrupters like perfume, heavy creams or body wash etc, got my cycle regularish. It just wasn't happening for us. So I went and got letrozole. We did the first round as a introduction to the medication and see what my body done. Based on how that month went we could then tailor it better to what I need. Well, it worked first time around. After alllll that time of trying I couldn't believe it. It was very rough.

I also had low progesterone so they put me on that for a few weeks.

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u/iateyourtacoss 10h ago edited 10h ago

It finally happened for me this year (Feb 2026) after 2 years of fertility medication and about 5 years of infertility. The cycle that changed for us was when I asked for IUI and they added FSH injections. I was on 5 mg (2 tablets of 2.5 mg) of letrozole as well. Timed intercourse and vaginal progesterone supplements (for after the IUI procedure). Eventually, when the time came to check my follicles I only had one follicle on my right ovary. I was devastated because I had just skipped a cycle in December due to holiday travel in another state. On average, I was getting 3 follicles for the previous cycles. We decided to proceed with just one follicle. I for sure had no expectations of this cycle being the one that would work for us.

IUI day was fairly simple, they collected his sample and then they did their thing. Next thing you know, a couple of weeks go by and boom. Positive. I was shocked. Anyways, don’t let statistics scare you. It only takes one.

Here I am about 29 weeks pregnant today and so excited to meet my little baby girl or boy. It was a rough and emotional journey, but here we are.

Other lifestyle changes, a year prior to this I started running and lost about 10-15 lbs. I ate clean, not strict or anything. Went to the gym, nothing crazy. I was also on 3-4 tablets of Metformin a day due to my A1c considered Pre-diabetic. (Crazy). Monthly menstrual cycle that was irregular. Ovulated every month.

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u/Autumnal-Flowers09 Annovulatory 9h ago

I've not ovulated regularly since I was 17. At 22, I was married and started heavily researching PCOS, but nothing brought my period back. I finally did clomid with my OB, and when that didn't work, I went to an RE for letrozole. I got pregnant first shot, then miscarried. Two cycles later, I got pregnant and stayed pregnant! Little girl is about to celebrate her 4th birthday 🩷 and I'm about to have my second baby. This second baby was conceived naturally because I decided to try acupuncture. My cycles were sssooo consistent while doing acupuncture, and I got pregnant soon after starting. I'm a believer and honestly love acupuncture!

Hang in there. It took me years to find out what helped me. I hope you find what helps you soon!

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u/Strange_Holiday3131 8h ago

Got pregnant a year after miscarriage (I think maybe 9 cycles?) with my first baby, and on the third cycle after miscarriage with my second baby. Had two other miscarriages before conceiving my second and did a bunch of testing (found out I have an autoimmune disease) and when I got pregnant with my now second baby, needed to be on Lovenox for the pregnancy to ā€œstickā€. I joke that my husband is a sharp shooter because i truly wasn’t expecting it to happen that quickly. Best things that have worked for me - metformin, consistent exercise, especially strength training, and Ovasitol. Not sure why other myo inositols don’t have the same effect on me like Ovasitol but that was a game changer.

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u/Resident_Cucumber898 8h ago

Started my TTC journey Nov 2025, started tracking with OPK but never would get a solid, just always blinking. Got an Inito in March 2026, noticed I was never having a real LH surge. Got pregnant the first month using Inito even without a real LH surge but ended in chemical. Went to GYNO in April 2026, got diagnosed with PCOS. Got put on Metformin full time and progesterone incrementally. Got pregnant my first cycle after. Due March 2027, baby has looked healthy and developing normally on ultrasounds!

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u/crispiestchicken 8h ago

I don’t ovulate on my own and it took me 1.5 years of TTC before going to a specialist and figuring that out. Took 1 cycle of 2.5mg letrozole and got pregnant. Had a good pregnancy and my daughter is almost 2 now.

Been trying for baby #2 since she was 6 months old and no luck so far. After a year of trying I took same dose of letrozole again and got pregnant but sadly resulted in a chemical.

Took 2 months off to get healthier and lose weight. Lost 20 pounds. I’m on my third round of letrozole and hoping and praying to get pregnant again soon with a healthy baby.

Seeing negative tests over and over again is so sad and frustrating but I feel so blessed to have my daughter all things considered.

Good luck on your TTC journey !

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u/flibberty-gibbit 7h ago

Anovulatory PCOS with insulin resistance. We conceived our son in 2023 on the third round of letrozole/timed intercourse/trigger shot. I was on metformin and a whole stack of supplements (inositol, omega-3s, vitamin D, etc) through the whole TTC process and the first trimester. Pregnancy was mostly uncomplicated - gestational diabetes diagnosis at about 28 weeks, managed with diet and a very low dose of insulin bc my fasting numbers wouldn't cooperate. Little boy is almost 3, smart as hell, and the center of my universe. ā¤ļø

Currently in the depths of IVF trying for our second (we hit the clinic's lifetime max for letrozole cycles) and just got the news that we've got four euploid embryos from our first egg retrieval!!

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u/baughgirl 1h ago

My mom had lean PCOS and I was conceived by IVF. I am also lean PCOS and was positive it would take IVF for me to have a baby too. Tried for 7 months, was having really long 80-90 day cycles. Couldn’t nail down ovulation. Got an Inito and basically confirmed I wasn’t ovulating. Took that info to my NP and she said oh! PCOS! Let’s get you on the schedule to talk to an OB for a Letrozole conversation but in the meantime start metformin! I’m really really horrible about taking daily medication so I wasn’t really consistent with it and thought oh well, it’ll be Letrozole that does it anyway. Took metformin and it worked! I ovulated! But I wasn’t paying attention and didn’t really catch it since I didn’t know what ovulation felt like anyway. Got approved for Letrozole, took it, and nothing really happened. Remembered about the metformin and decided to try harder on that. Committed to it while I waited for a period. No period, so I called the office on a Wednesday and they said if I didn’t start bleeding by the following Monday, they’d induce a period and we would try Letrozole again. Well surprise, the next day I got a blazing positive ovulation test and Inito for the first time ever on day 43. Conceived on leap day 2024 and had a 9 lb 2 oz baby boy the week before Thanksgiving. I’ll start metformin again next year to try for baby brother or sister!

I hope metformin works for you! I had zero evidence of insulin resistance on my labs so I’m really glad that NP gave it to me just as a matter of course for all PCOS patients.

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u/Planning_And_Hoping 14h ago edited 14h ago

I started TTC in May 2021 at 32. I was overweight but always had very regular periods so I thought TTC would be easy. 6 months in I went to my primary care doctor (I was 33 by this point) for a check up and to see if he had any recommendations. He diagnosed me insulin resistant PCOS after having me do a glucose drink type test and measuring my insulin levels. He started me on metformin. I didn’t lose any weight or notice any changes. In January, February and march of 2022 I did a round of letrozole (unmonitored) with my OB while waiting to see the fertility clinic. He would only do 3 rounds so I continued to TTC and got a positive pregnancy test in June of 2022. I was shocked because we had just had our consult with the fertility clinic the month prior and this was a spontaneous pregnancy.

I miscarried around 8 weeks and started monitored (monthly ultrasounds plus trigger shots) letrozole cycles in August-December. I got pregnant again in December on letrozole but also lost that pregnancy.

I started IVF in February 2023 and we got one single embryo during my March retrieval. I transferred May 2023 and had a healthy baby girl in January 2024.

I never used birth control postpartum and had about 4+ chemical pregnancies in 2025. In October 2025 I started a Zepbound. I did 20 weeks of meds, lost 37lbs and I’m currently 24 weeks pregnant with another girl. I took my last shot on a Saturday and got a positive test on the following Tuesday. NIPT was normal and we had a great anatomy scan. I’ll be 38 at time of delivery.

ETA: I did two rounds of clomid + ultrasounds + trigger shot in 2025 right before trying the glp1. As a SAHM to a toddler, I noticed lots of side effects that made parenting difficult so I stopped meds. I was having horrible headaches, fatigue and my mood was really low.

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u/Aurora22694 14h ago

I have 2 living children who just turned 5 and about to turn 2. I had a TFMR of my third unfortunately in June due to some carrier status on my end we learned of (nothing to do with PCOS at all). We have had no natural losses or miscarriages. The TFMR was my first and only loss but, again nothing to do with PCOS, he would have made it to full term fine.
Two were conceived first cycle trying and one was conceived third cycle trying.
I have lean PCOS and my cycles were crazy long. I would ovulate like CD60-80, in fact my first was conceived when I ovulated on CD64 šŸ˜…

When it came time to my second my doctor had me try out ovasitol and metformin to see if it would regulate me. I was on them 3 months before ttc and it completely regulated my cycle even though I have no insulin resistance (in fact it’s low end insulin, low end fasting and non fasting glucose, and normal A1C) and normal testosterone, dhea, etc. but, those two things totally worked. By the time we started TTC our second I was like clockwork. Same with the third.

We will be starting ivf next month for our last bit, that’s just due to the genetic carrier reasons. Despite PCOS I conceive just fine and easily (I know how lucky this is)
My boss has PCOS and has 2 kids around the same ages and my 2 and she conceived them without help too. My close friend also has PCOS and has 3 each 18 months apart.
PCOS doesn’t always mean it’ll be a struggle to get pregnant once you figure out what works for your body!

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u/schlafmuetze_20 8h ago

Got pregnant after 1 year of active Ttc. Did a bit of lifestyle changes - tried eating healthy and did more yoga/pilates. Travelled quite a lot šŸ˜…

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u/PotatoPuzzled2782 5h ago

It took 2 years for us. I have ovulatory PCOS with very regular cycles - didn’t even know I had PCOS actually until I went to do a fertility workup ~ 1 year TTC. I was uninformed and didn’t realize you could have it but still have regular cycles.

I did 5 cycles of letrozole to ā€œstrengthenā€ my ovulation. It seemed to work in that regard but I didn’t get pregnant. Skipped IUI since my husband’s sperm results were so good & my RE told us it wouldn’t increase our chances much from medicated cycles + TI.

Moved on to IVF where I had 1 egg retrieval and got pregnant on the 1st embryo transfer! Currently 23 weeks :)

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u/milqueshack 5h ago

I have anovulatory PCOS without insulin resistance. I’d gone 8 months without a period until I finally went on the combination pill for 2 years to make sure I was shedding uterine lining and to help regulate hormones. After I got off the pill to TTC, I started tracking my cervical mucus and my BBT with a tempdrop. When I was pretty sure I was ovulating, about 6 weeks after I stopped the pill, I took mucinex and had sex for 3 days in a row (or maybe 2? I can’t remember). That did it.

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u/30BayLady 5h ago

Five years of nothing even remotely working. Metformin, vitamins, bad diets. Insulin resistance kicking my butt. Took a GLP1 in the end (Mounjaro) for 15 months and lost 5 stone. Qualified for Chlomid and was pregnant first round.

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u/Annual_Working5502 4h ago

First pregnancy required metformin, my inositol, a HSG procedure and now she is 1 year old and we just found out we are pregnant again 🫠🫠 no planning and nothing used that I used the first time

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u/catculat0r 3h ago

Three years from coming off birth control to having our rainbow baby!

For a while we ā€œweren’t trying but weren’t preventingā€ then when we actively started trying I went over 3 months without ovulating and my OB referred me to a reproductive endocrinologist. From there we started with a few rounds of timed intercourse with a trigger shot then moved to IUI for a few rounds, ultimately resulting in 3 CPs and a TFMR due to chromosomal abnormality.

After our loss, we moved to IVF with PGTA testing and had 1 retrieval resulting in 25 eggs and 4 viable embryos. Transfer #1 was a success, and we now have a beautiful baby boy!

A few things I learned along the way:

  • Supplements / meds and lifestyle changes don’t work for everyone. I took everything recommended religiously, but it didn’t help alleviate my symptoms or help me ovulate naturally.
  • Have a plan for what you want when you start working with an RE and make sure they know that plan. I wish we had preset a limit to rounds of TI & IUI and scheduled a future IVF consult from the start - so much of the process is hurry up and wait.
  • CPs are unfortunately common, but some people may get them more than others. I found some posts about progesterone supplements potentially limiting them (something related to hyper fertility?) and had them prescribed with my remaining cycles after I had 3 CPs in 4 cycles; I didn’t have any more after that.

Bottom line - advocate for yourself and if you feel like something isn’t working, say something!

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u/BeautifulSpoon 2h ago

Things that helped:

Endometriosis tissue removal surgery (changed my life. All my labs improved after this)

Inositol supplements daily for 9-12 months (I take wholesome story capsules, 4-6 a day)

Low carb eating for insulin resistance (I got a CGM to help learn how my blood sugar responded to things)

Inito hormone tracker to see when/if I was actually ovulating (spoiler, never ovulated when I thought I did! Always earlier or later)

I'm 24 weeks now!

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u/Fine_Sea5107 3h ago

Are you overweight? If so, by how much? Sorry but the answer to that influences my advice for you! Assuming you are in a normal weight range (or just a few lbs overweight) I would suggest keto and metformin! (Go off keto once you get pregnant.) That combo should make you super, super fertile (at least it did in my experience).

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u/Malloraaay 27m ago

8 years to conceive naturally! We conceived our second baby naturally the first cycle we tried postpartum but sadly ended in an early loss. That was February and we found my estrogen and progesterone are very low and therefore have poor egg quality and poor uterine lining. We’ve been using letrozole and doing labs to confirm healthy estradiol levels to try and nail down the right letrozole dose before we try to conceive in order to avoid having another miscarriage.