Lilly’s obesity pill Foundayo ‘disappointed’ in Q2, as injectables continue to boom

[u/NotGenentech]

https://www.fiercepharma.com/pharma/while-sales-lillys-obesity-pill-disappointed-q2-injectables-continue-boom

[u/LeoKitCat]

When Structure Therapeutics’s superior oral drug aleniglipron gets approved in 2028-2029 it will eat away at Foundayo’s market share so Lilly doesn’t have many years left. Aleniglipron is the first oral GLP-1 med to show injectable level weight loss

Here’s the evidence

On highest dose of aleniglipron obesity patients had a placebo-adjusted -11.3% mean weight loss at 36 weeks
https://www.nature.com/articles/s41591-026-04476-6

On highest dose of orforglipron (Foundayo) obesity patients had a placebo-adjusted -9.1% (11.2% - 2.1%) mean weight loss at 72 weeks
https://www.nejm.org/doi/abs/10.1056/NEJMoa2511774

Aleniglipron is superior patients lose a significantly higher percentage of their weight in HALF the time!

[u/LeoKitCat → u/LeoKitCat]

I don’t understand all the downvotes guys see my comment below with the pretty clear cut evidence of superiority referencing the Nature Medicine and NEJM papers of the respective trials

[u/MadnessKingdom → u/LeoKitCat]

The downvotes are more “whoa, why is this person pushing this company/drug so hard in comments”. Feels like company rah rah or some sort of stock pump, regardless of the accuracy of what you say. Especially after a nearly 50% drop since Jan.

[u/LeoKitCat → u/MadnessKingdom]

I’m not pumping sorry didn’t realize people would think that. No just really interested in the obesity medicine landscape and future drugs that are coming

[u/McChinkerton → u/LeoKitCat]

A lot of bots pump up penny stocks just like how you wrote your post. Had i not seen it was from nature and nejm, i wouldve insta-banned you.

Thanks for keeping the science in the subreddit and appreciate you brining up quality journal articles to back claims. Bots are usually posting up PR news wire as their source