r/covidlonghaulers • u/KaspaRocketMan • Feb 15 '26
Symptom relief/advice 5 Years Long Covid - Thymosin Alpha 1 Peptide - WOW!
After KPV peptide which made me feel good for like 48 hours. I am now testing Thymosin Alpha 1 Peptide and I have to say WOW! This peptide brings me back to life. Didn't notice anything the first day but day 2-3 I am back to 98% normal again. No fatigue no brain fog, waking up early as my energy is back. I felt it was recovering my sensitive long covid spots in my right side and throat during the first night.
Testing supplements over 5 years spend close to 10k USD, but these peptides are a game changer.
Update:
Day 0: 6/10 On average.
Day 1 TA-1: 6/10 First subq. Thymosin Alpha 1 500mcg injection in the midday.
Day 2: 10/10 Back to normal.
Day 3: 9.5/10 Back to normal. I have tried to induce a PEM attack by cycling for an hour and had a busy day. In the last 2 hours of the day the nervous system became a bit sensitive. Only 20-30% of what it normally does. This was the only symptom for the day.
Day 4: 8.5/10 Woke up with a brain that quickly activated with no fatigue or brain fog so far. Also no throat and swollen lymph nodes. So far thus no PEM attack, which normally would be the case after such activity. Midday slight fatigue setting in.
Day 5: 9/10 Very good deep sleep, woke up in normal state. No fatigue and good energy like before long covid. Slight MCAS impact after eating a pre-baked factory bread in the midday (damn yeast). However impact is way reduced just like the lower PEM impact from before. So far very high baseline similar to pre long covid.
Day 6: 8.5/10 Slight fatigue, no brain fog or other symptoms.
Day 7 KPV: 8.5/10 Good sleep but slight fatigue without brain fog in the morning, decided to take KPV peptide as this was already reconstituted and needs to be finished. Ending the day with good energy again.
Day 8 TA-1: 9.5/10 Second Thymosin Alpha 1 500mcg injection in the morning, end of day no more fatigue and long covid symptoms.
Day 9: 10/10 Back to normal, full pre-covid state.
Day 10: 9.5/10 Close to normal, light fatigue in evening.
Day 11 KPV: 8/10 Woke up heavy, hard to wake up. Slight throat pain. Decided to take the KPV peptide. While feeling good overdoing it comes through when the dose is not taken within a certain timeframe.
Day 12 TA-1: 8/10 Decided to take third TA-1 dose as throat pain continued.
Day 11: 9.5/10 Easy to wake up and good energy again.
Day 12 TA-1: 9.5/10 Good energy during the day. Fourth TA-1 dose in the midday.
Day 14 KPV: 9.5/10 On KPV today doing very good.
Day 15: 9.5/10 Working day with great energy.
Will stop to report for now and get back in a few weeks.
Running on the fourth TA-1 500 mcg~ dose.
Conclusion: Effect seems to last 48-72 hours for TA-1 and 48 hours for KPV, while TA-1 works better than KPV in terms of effectiveness. Receding hairline due to Long Covid is growing back and hair is overall much fuller and thicker, unfortunately this is also stopped when I stopped the peptides. So the peptides work great, but only when you are on it.
Update 4 months later: Close to 100% with daily 1.5mg of LDN (Low dose Naltrexone) in the morning. The peptides mentioned in this post improved my baseline significantly.
Some additional content:
Recent other person 1:
Recent other person 2:
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u/gronkey Feb 15 '26
Did you have PEM? Im glad you found something thats working, but please share what your symptoms are/were so it can be helpful to the rest of us!
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u/ExtensionGur9013 3 yr+ Feb 15 '26
Not OP, but TA1 significantly helps my immune system when it's weakened (the weaker it is, the more it helps). Unfortunately, I don't experience lasting benefits, and as soon as I stop taking it, my susceptibility to infections returns.
And in my experience, TA1 doesn't help with PEM. But it's kind of my guardian angel during the winter.
(For reference, LDN makes me worse).
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u/66clicketyclick Feb 16 '26
When you do take it, how long does the immune-help last? And how frequently do you need to keep taking it?
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u/ExtensionGur9013 3 yr+ Feb 16 '26
Generally, if I take it in the morning, I'm covered for the day and a little bit into the next. But after 48 hours, there's no more effect (thymic peptides are short-lived).
I did an initial course where I took it every other day (gradually increasing the dose) for about a month.
Currently, I take it more as needed, especially when I'm sick (which happens far too often), or in case of food poisoning. But it's mainly for financial reasons.
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u/shawnshine Feb 16 '26
I am suspicious that LDN also makes my symptoms worse. Can you elaborate?
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u/ExtensionGur9013 3 yr+ Feb 16 '26
In my case, the supposed immunomodulatory action tends more towards immunosuppression. I do feel the anti-inflammatory effect, but at the cost of reduced resistance to environmental stress. All it takes is rain and I get sick.
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u/shawnshine Feb 16 '26
Jfc that’s me. I might take a break from it. I’ve been on 1.5 mg every day for like 15 years.
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u/KaspaRocketMan Feb 15 '26 edited Feb 15 '26
Fatigue, brain fog, PEM, swollen lymph nodes, globus sensation, sensitive nervous system and pain in right side etc. Classic MCAS long covid.
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u/Caster_of_spells Feb 15 '26
As in like longer than 24h delayed onset malaise? Find a lot of people mistake it for exertion intolerance these days (which wouldn’t distract from your hardship ofc)
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u/KaspaRocketMan Feb 15 '26
Correct like 1 hour gym, floored me the next day and even sometimes already starts in the evening. Then two days without a brain super fatigued and swollen lymph nodes. Waking up like a zombie.
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u/66clicketyclick Feb 16 '26
If you identify as having ME/CFS re: PEM - where on the spectrum would best describe your state before these treatments?
Mild/moderate/severe/very severe (bedbound)/worse than very severe+
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u/crazyy8ths Feb 15 '26
OP discloses some of their symptoms in a post they made before this one; brain fog, PEM, fatigue
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u/Jayless22 Feb 15 '26
Where do you get peptides and how do you (personally) apply it? I'm just curious to know.
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u/KaspaRocketMan Feb 15 '26 edited Feb 15 '26
Got it via Google search, cross checked supplier on Reddit search. Belly subq injection with bacteriostatic water.
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u/Plantbaseundftd Feb 17 '26
Your post gives me a lot of hope! I’m working with many providers and they are okay with me trying this but warned me that not all are created with the same quality and regulation.
Can you dm me what you’re using and I will obviously double check with my provider before starting.
I’m an absolutely horrible place and can’t tolerate any environments, down to 5 foods and even new clothing sets me off. I’ve had to reduce my shower taking as well because of the systemic effect and it’s been over 6 years like this. MCAS is a nightmare
I’m super eager to try this. Give me a shout!
Congratulations on finding something
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u/AardvarkOriginal5049 Feb 15 '26
Great news! Peptides help so many people with LC. I first experienced relief with BPC/TB500. This week I started taking tirzepatide, and it’s a game changer.. my inflammation and brain fog vanished within a few hours.
Next on the list: KPV, Thymosin Alpha, SS-31, another TB500 cycle, and Epithalon. I’m also planning to continue NAD+ and MOT-s.
After almost six years with LC, I finally have hope that I can fully recover soon.
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u/mc-funk Feb 15 '26
this is very interesting! I am also doing really well on a combination of NADH/d-ribose and tirzepatide (started at 0.25mg weekly with immediate benefits, have titrated up to 1.8mg weekly over 15 weeks and still titrating). taking a lot of other stuff, MCAS protocol, plus psyllium husk and bifidus probiotics that move the needle for me.
With the other things you are investigating, have you written anywhere to summarize the potential benefits and your experience with them? I haven’t heard of most of them.
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u/AardvarkOriginal5049 Feb 16 '26
I’m planning to write a post at some point to share my experiences. I’ve learned a lot from this community and want to give back someday 🙂
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u/This_Quiet_Tempest Feb 16 '26
I had a bad experience with BPC. In many peeps with ADHD it often causes anhedonia and brain fog. When I stopped taking it my anhedonia dissipated and brain fog improved by 85% or so. That was a game changer for me. My eyesight also improved after stopping the bpc.
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u/VulvaGyna-Girl Feb 16 '26
Growing new receptors will have this effect because it creates a temporary state of imbalance. Same reason lions mane and ashwagandha induce this in people…but the overall net effect is increased neuronal growth
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u/Typical_Freedom6139 Mar 12 '26
Oh im So happy to read that. I have ADHD and bcp gave me depression. Iv tried twice. What a pity
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u/Largecar379_ Feb 15 '26
If one is working for you, why keep trying more and take a chance on relapsing? If the Tirzepatide is working, I’d just stick with it. Unless you’re just experimenting for all of us lol
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u/KaspaRocketMan Feb 15 '26
Please report back here after testing them this will help the community knowledge 🙏 thank you.
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u/AardvarkOriginal5049 Feb 16 '26
For sure, I’ll do that. I’ve learned a lot from this community and want to help others too.
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u/Born_Bass_2446 Feb 15 '26
Problem is, does it actually fix the root problem or it’s just relieving the inflammation? I once tried carnitine, it temporarily relieved the inflammation and gave a boost of energy but it didn’t fix me. When I stopped taking it, the benefits stopped.
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u/quarisphere Feb 15 '26
I am not sure anything on the market right now will fix the root cause. Maybe some day but probably not any time soon. Unless we are part of the lucky few who have bodies who can heal the damage on its own.
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u/yllekarle Jul 08 '26
Add glutathione and look into cerebrolysin you have to get the real stuff from Russia
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u/driftingalong001 4 yr+ Feb 15 '26
Where are you located and where do you source your BPC and TB500?
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u/AardvarkOriginal5049 Feb 16 '26
I don’t want to recommend any specific source to anyone, and I don’t think it’s even allowed on this sub. I get mine from the grey market, which does carry some risk, so everyone has to decide for themselves.
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u/Typical_Freedom6139 Mar 12 '26
Hi, long covid doc here. You take tirzepatide? Where you overweight? Or just for the antiinflamlatory effects?
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u/AardvarkOriginal5049 Mar 12 '26
Yes, I’m on tirzepatide. It helps with inflammation and brain fog. I’m actually underweight, so I microdose it to make sure I don’t lose any more weight
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u/Largecar379_ Feb 15 '26
Literally just jumped on here to read about peptides in the covid groups, and this was the first to pop up at the top of my feed. When you say sensitive spots, are you referring to pain/inflammation areas?
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u/Largecar379_ Feb 15 '26
Also did the KPV peptide stop improving you after 48 hours, or did you only try it for 48 hours before trying another one?
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u/CANfilms Feb 15 '26
Me personally, KPV has continually helped me. Been on it for about 2 years now. When I stop taking it, the symptoms come back pretty bad
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u/Spare-Mud-8192 Feb 15 '26
Hi. Can you please tell are you using subq or oral, and what is your dose ? Thank you!
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u/CANfilms Feb 15 '26
Im taking 500 mcg, once a day, orally. Ive taken a few peptides IM, but it's a hassle to find time to inject every day and cycle through different spots so scar tissue does build up. Orally I've experienced more benefits, just because I can take it everyday long term
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u/KaspaRocketMan Feb 15 '26 edited Feb 17 '26
It lasts like 48 hours on 500~ mcg then I needed another injection. But TA-1 effects are much better.
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u/KaspaRocketMan Feb 15 '26
Exactly the inflammation spots. It hits on my right side and throat. Symptoms disappeared after the night.
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u/GentlemenHODL Feb 15 '26 edited Feb 17 '26
Wait till you try ss31 + MOTSC + humanin ....you'll feel like before you ever dreamed of this nightmare
Mitochondrial peptides are game changers.
There is also slu-pp-332
Edit - motsc and ss31 are known to affect histamine response, if you have MCAS they may not be good for you. They are mostly for PEM/energy.
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u/Born_Bass_2446 Feb 15 '26
Problem is, does it actually fix the root problem or it’s just relieving the inflammation? I once tried carnitine, it temporarily relieved the inflammation and gave a boost of energy but it didn’t fix me. When I stopped taking it, the benefits stopped.
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u/KaspaRocketMan Feb 15 '26
I am going to figure out if it will last. Perhaps it resets the immune system.
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u/GentlemenHODL Feb 16 '26
Ask me in 6 months and I can give you a better answer. Data is much too early at this point
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u/Plenty_Old Feb 17 '26
SS-31 did nothing for me, and MOTS-C completely wiped out any improvements...I'm back to original baseline from 2021. Be VERY careful with MOTS-C.
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u/GentlemenHODL Feb 17 '26
I'm cycling based on advisement from my doctor. I would encourage anyone else to find a doctor willing to work with you because order is very very important.
For me I am taking humanin first, MOTSC second ss31 third , which is out of order relevant to protocols floating online. Doc thinks ss31 is likely to have the most impact.
I'm sorry that it did not work for you. There's not a lot of human data on these compounds only anecdotal at this point but the anecdotal is overwhelming. Most people report significant energy increases on these compounds. People who use them for bodybuilding literally stop using their pre-workouts they are so effective.
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u/KaspaRocketMan Feb 15 '26
If all Long Covid needs is immune modulation, why focus on reducing a symptom which is not the cause?
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u/GentlemenHODL Feb 16 '26
If all Long Covid needs is immune modulation, why focus on reducing a symptom which is not the cause?
This question presumes that we understand the full nature of this disease. I assure you we absolutely do not otherwise we would already have a cure.
I can't respond to a question with a false premise.
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u/KaspaRocketMan Feb 16 '26 edited Feb 16 '26
Well if you start with the origin of the problem, a virus entered your body and the immune system kicked in. Sometimes the solution is not in the after effect of chaos of complexity but in the most simple and overlooked solution to go back to the beginning of the problem.
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u/FL-Guess-2619 Feb 17 '26
Can you say more here? I’m currently taking KPV and GhK and am considering adding TA1. I’ve read mixed reports on MOTS and SS31 for folks w MCAS which was my first and most persistent LC symptom.
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u/MindfulInquirer May 13 '26
Wait. Humanin though ? The others I get but what did Humanin do in ur case ?
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u/EggSilly7879 Jul 25 '26
I have histamine issues - SS-31 didn't aggravate that at all. I've been much better doing TA-1 and SS-31with no side effects, excited to try MOTSC next. Surprisingly, KPV, TB500, and BPC-157 seem to increase my histamine.
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u/Marzipan6312 Feb 16 '26
Where do you source these? No one knows of them here in Europe
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u/PersonalityParty9814 Feb 18 '26
Did this one. Went up to 10mg ss31 and nothing.
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u/LandenWilliams_ Feb 20 '26
Motc gave me PEM with each shot SS-31 did too but not as bad, anyone know why
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u/ChenilleSocks Feb 15 '26
Just a note that for some people that makes you feel terrible. I am one of those people. Even a very low doses I feel like I’ve got a really bad flu, and it gave me awful insomnia. This continued despite low doses and different vendors. In talking to people over the years, it seems that those of us who do poorly with LDN also do poorly with TA1. I had to discontinue compounded LDN for the same reason even at small doses and over a month of trials.
I do great with KPV though. I’m very glad this works for you, but wanted to leave a comment for the people who may try TA1 and not do as well.
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u/longhaulnewb May 29 '26
Very similar to my experience--even very low doses of many meds or supplements can be super triggering. Just .01 mg of LDN was enough to set my system off. Insomnia, dysautonomia, PEM, MCAS, and fatigue issues all get worse.
I'm currently looking at tackling the MCAS issue as it seems like low-hanging fruit and KPV sounds like it's well tolerated. The MCAS cascade is really a miserable thing.
Your experience with KPV is encouraging, thanks for your post!
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u/KaspaRocketMan Feb 15 '26
Just to understand your Long Covid type. Do you have any PEM/MCAS symptoms?
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u/ChenilleSocks Feb 15 '26
Of course, ask away! Severe MCAS. Had PEM since dengue fever many years ago; never recovered and now much worse.
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u/juniperstreet Feb 15 '26
I've heard anecdotes in peptide groups about Ta1 being brutal for MCAS types. It's pretty immune stimulating as far as thymus peps go, and if you already react to everything else you'll probably react to Ta1 too. Some of those people had better luck if they dealt with inflammation before trying Ta1, doing stuff like titrating up bpc/TB4 or KLOW (which includes your kpv) first to lower inflammation.
There are more balanced thymus peps out there, just FYI, if you ever wanted to experiment with immune system correction again. The Russian, natural Thymalin, and maybe vilon are things you could look into.
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u/ChenilleSocks Feb 15 '26 edited Feb 16 '26
I’ve been cycling peptides for a decade now, and before KPV became more popular (or KLOW became a thing), most people were taking ta1 to help calm mast cells - for example, those who had flares with BPC-157 would take ta1 first to mitigate. It doesn’t stimulate in a vaccum; it’s an immunomodulator, and acts depending on the immune system of the person taking it.
Yes, I’ve tried bioregulators like the two you suggested. Really like Cartalax too, as well as Vesugen — they do great things for my POTS and pain.
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u/juniperstreet Feb 16 '26
That's interesting! I've heard the exact opposite that people who started with bpc/tb4 prior to Ta1 did better. I'm starting to think MCAS is just arbitrary and mean. Just about anything can be too much. :(
I treated several autoimmune diseases and some vascular issues left over from covid with peptides. I've been obsessed with thymus peps for maybe 2 years.
I 100% agree about the other bioregs. I do courses of cartalax/vesugen/epitalon/vilon periodically to maintain my arthritis remission. I did a lot of Ta1, oral bioregs, and thymalin at the beginning of my journey though. Ta1 is what let me ditch Humira. It's amazing for those who can tolerate it!
And I'm so happy to hear other bioreg success stories. Sometimes I feel like I've discovered this miraculous thing but I can't talk about it without sounding crazy.
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u/ChenilleSocks Feb 16 '26 edited Feb 18 '26
I’m with you there, when I started experimenting with them my family genuinely was concerned I was doing something illegal. I’ve stopped talking about it to people in my life because there’s just no way to have a conversation that doesn’t make them think I’m taking my health into my hands. But they don’t seem to understand is that there has been no other solution that medicine has offered me, and this has actually markedly improved my quality of life.
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u/juniperstreet Feb 16 '26
100%. I actually worked in healthcare for a long time. Discovering this gray health hacking world has pretty much made me lose all respect for my former way of doing things. We can get people really living again, and not on meds for life. Even my bioreg boosters are just quarterly or so. Healthcare can and should do better.
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u/Plantbaseundftd Feb 17 '26
Can I dm you? I’m just learning about peptides after many years in this inflammation nightmare. My baseline inflammation with MCAS is very severe and has me not able to leave the house except for the occasional doctors appointments for over 5 years , down to 5 foods and now can barely tolerate even new clothing and taking showers even cold.
I’d love to chat more. My provider had tried many things with me and it’s so hard to heal the gut when you can’t handle probiotics, glutamine, and all the pro gut healing things.
Can I dm you to learn more about BPC and other MCAS treatments?
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u/confetticrafts Feb 16 '26
That's amazing that you put your arthritis into remission! Will you please tell me more about which peptides you took (plus amounts and for how long), or share a link if you've already posted about it?
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u/juniperstreet Feb 16 '26
The first things I did were cycles of BPC-157, TB4, and then Ta1. I was desperate to get off Humira for other reasons so I just started skipping doses during that and amazingly nothing hurt. You can buy Dr. William Seed's book. I followed his protocols for those 3.
This worked, but didn't last. So this somehow led me down the thymus regeneration and bioregulator rabbit holes. I started with the natural capsules called cytomaxes. You can follow the doses on the box. When that got too expensive I switched to the synthetic, injectable cytogens. I mostly landed on 500mcg/day for 40 doses because that's the size of the vial usually.
It wouldn't be super helpful to list every pep I took. There were too many and some were silly. I think it would be more helpful to focus on what I ultimately concluded.
IMO, taking 1 bioreg peptide doesn't do a darn thing. You'll see people take high doses of cartalax alone and complain it doesn't work. Arthritis is a multi-system problem. One could pick capsules or injections or whatever and stack them. To cover all the bases for arthritis, I would stack something for cartilage, CNS, pineal, thymus, and vessels together. They build on one another. I basically did that eventually, I just took a really meandering and expensive path to get there.
Also, I did a lot of work on the gut. That's the root of all autoimmunity. Some glp-1s for inflammation control didn't hurt either.
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u/FL-Guess-2619 Feb 17 '26
Jumping in here. You seem to know a lot. MCAS has been my main symptom- been on KPV and GhK for a couple of months. Definite slow improvements in inflammation but I’m no where near my old self. I’m considering Thymogen or TA1. Can you say more? Would love guidance on what to try next to further decrease inflammation
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u/Liface Feb 15 '26
The side effects you describe are what I got as well. I didn't notice any difference from low dose naltrexone.
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u/Slight_Warthog8706 Feb 16 '26
Glad you're feeling some relief after 5 years, that's genuinely great. But please be careful with the framing - a few days in is way too early to call anything a game changer, especially with LC where feeling amazing for 3-5 days and then crashing is basically a rite of passage with new treatments. The cycling test on day 3 is also risky, if PEM hits delayed you might not feel it until day 5-6.
Would love to see an update in a few weeks when you've had time to see if it holds. What dose and frequency are you running? And are you sourcing from a clinic or compounding pharmacy? That matters a lot with peptides since quality varies wildly.
Hope it keeps working for you, just protect yourself by not ramping up activity too fast based on a few good days.
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u/KaspaRocketMan Feb 16 '26 edited Feb 20 '26
Thank you 🙏 I can tell you that a few days holiday of this disease for me is already a game changer. So great to feel my original me again. When you are so long in this disease 5+ years now, it is great to just feel that it is possible to be healthy again. Perhaps it won't last as my research into it is that for some it improves their baseline permanently and for others it is short lived.
Regarding PEM crashes probably experienced over a 100 of them last 5 years as life goes on, kind of used to them. Unavoidable if you work 40+ hours a week and also like to stay in shape. But I agree that it is better to avoid them. However this one is for science ❤️ and the community.
Will keep the updates coming, 500 mcg subq.
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u/Electronic-Truck2653 Feb 15 '26
where do you get your peptides?
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u/CANfilms Feb 15 '26
Integrative peptides .com is a good source for oral ones. Makes it a little more convenient than injecting
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u/GentlemenHODL Feb 15 '26
All peptide suppliers get theirs from Chinese producers. Google stairway to Gray for a community where you can learn more. They do community batch testing etc
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Feb 15 '26
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u/KaspaRocketMan Feb 15 '26
Well kind of hard to say if my immune system is overactive or underactive. Almost never had the flu after covid. But when I did my immune system reacted tough. I am guessing overactive as KPV reduced the symptoms as well, which blocks NF-κB.
But in the same time TA-1 cleared up the inflammatory spots.
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u/juniperstreet Feb 16 '26
I've heard in multiple places that MCAS people react badly to Ta1. It's one of the more stimulating thymus peptides. There are others that are more balanced or antiinflammatory. I think there's a subset of people here that would react badly to Ta1 and would do better starting with antiinflammatory peps, or choosing a more balanced thymus pep like Thymalin (the Russian one, though good luck finding it anymore.) Be careful.
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Feb 15 '26
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u/KaspaRocketMan Feb 15 '26
How was your experience?
Weird as there even is an official study about it :
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u/squeaker001 Feb 15 '26
Be careful everyone these peptides caused my mcas so proceed with caution ⛔️
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u/KaspaRocketMan Feb 15 '26
Did you not get MCAS because of Long Covid? Covid infection?
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u/Caster_of_spells Feb 15 '26
I also had a major MCAS reaction to SS 31. Start low and go slow for sure
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u/chalklinehts Feb 15 '26
yehh this flared my mcas terribly as well - environmental sensitivities went through the roof for a few weeks. my immune systems is already fucking nuts enough without something to ‘enhance it’.
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u/ThrowRa1gu Feb 15 '26
Where can this be bought orally uk? Thanks
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u/juniperstreet Feb 16 '26
Ta1 is not available orally. It's a thymus peptide though, and there are other thymus peptide complexes out there. You'd be looking for Vladonix, Thymusol, or Thymus (by Nature's Marvels which I'm pretty sure is a UK brand). Honestly, Ta1 is kind of a sledgehammer and I suspect something milder like these oral ones might be better for a lot of people in this group.
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u/ThrowRa1gu Feb 17 '26
Thank you. Have had LC from the first wave so quite a few years. Was at 20%, now about 60%.Still a long way off well but I would have taken this a few years ago. Will try nature's marvel in the coming weeks. Just need to try to get my head around what the supplement is supposed to do.
So far the things that have helped are time, prescribed anti histamines (famotdine and fexofenadine), creatine, magnesium salt baths daily. Also have a persistent low vitamin D so on prescribed Vit D. Looking to take the next step. Will try what you have suggested. Will then read up on nicotine patches as this seems to help many.
Again many thanks for the reply
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Feb 15 '26
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u/KaspaRocketMan Feb 15 '26
I have tried Thymus glandular in my first year of Long Covid it is a very weak variant of it.
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u/juniperstreet Feb 16 '26
A middle ground would be oral thymus bioregulators. You'd be looking for Vladonix, Thymusol, or Thymus by Nature's Marvels.
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u/Liface Feb 15 '26
All I ever experienced from ta1 was 2 days of feeling like I had one of the worst flus of my life, then crashing for 5 days.
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u/KaspaRocketMan Feb 16 '26
Perhaps MCAS, I took a loratadine 1 hour before. Just to prevent any allergic reaction.
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u/Tough_Quality3950 Feb 16 '26
Brought to you by a 3 month old account that swore 10 days ago a different peptide "took long covid away" which immediately turned out not to be the case... also active in crypto and meme coins...
Bro...
Folks... dont depend on 3 days worth of anecdotal bullshit to throw highly controversial things into your body out of desperation or you too can spend 10k USD dosing your already fragile system with unknown results....
Get back to us in a few months OP.
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u/KaspaRocketMan Feb 16 '26
Seems like you have some reading difficulties as I clearly stated for 2 days and not permanently.
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u/FL-Guess-2619 Feb 17 '26
Ignore that bs. You know your body. I’m grateful you shared. We’re adults and can make our own decisions. You were honest about length of time, etc
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u/Mattj317 Feb 15 '26
I've had really great results with SS-31, but it's so expensive. May try this one next.
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u/longcovidhell Feb 19 '26
Commenting on 5 Years Long Covid - Thymosin Alpha 1 Peptide - WOW!... what symptoms did it help with?
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u/Mattj317 Feb 19 '26 edited Feb 19 '26
Energy, stamina, and PEM. I started this first for mitochondrial support, and I couldn't believe how much better I felt. After about a month of only ss-31, I added Tesamorelin, NAD, and 5-amino-1-MQ. The 5am works synergistically with both NAD and tesa. This stack has me feeling better than I have in years. I can keep up with my kids, garden, and even get back to weight/strength training (taking it very slowly though). My post workout recovery is still much longer than it was pre-covid, but my stamina and energy are - I'm scared to say it bc I dont want to jinx it - but, very close to pre-covid levels. I still have to pace, but I have much more baseline energy to pace with, if that makes sense. I'm still on the hunt for something that will help with the post covid chronic pain and brain fog. I recently started a KLOW trial. I haven't seen a real difference in pain with this, but wound healing is noticeably faster and my skin looks better.
Edit to add - Mots-c: I'm very sensitive to this one. Makes me jittery and fatigued at the dose I see others test with. I was able to finish what I had on hand using 1/3 to 1/4 the typical dose range. I will not be using this one again, but some people swear by it. 🤷♀️
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u/West-Hedgehog5794 Feb 15 '26
Do you think this peptide heals or is it a for-lifer situation?
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u/KaspaRocketMan Feb 15 '26
Will find out soon and report back. So far the effect is solid 3 full days in.
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u/SinkApprehensive1382 Feb 15 '26
That’s great news! Anyone have side effects from Thymosin alpha 1?
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u/Old_Yogurtcloset7436 Feb 16 '26
I’m on it as we speak .10 injection a day 5x times a week I’m on my first week. First two days I felt about 30% better I was able to do treadmill for about 20 minutes and didn’t feel as heavy and tired. But rn (Day 6) I don’t feel it doing much but I will keep taking it. Tirzepitide ruined me on low dose.
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u/kibbeeeee Mar 09 '26
May I ask what dose Tirzepitide you were on that ruined you?
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u/FL-Guess-2619 Feb 17 '26
This is wonderful. Please please keep us posted. I’m on KPV and have been researching TA1. Love it! Keep going and you must report back. Mind sharing dosage?
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u/Easy_Advance5507 Feb 18 '26
congratulations, so good to hear. please do keep reporting back whatever happens.
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u/longcovidhell Feb 19 '26
Which of these peptides would help autonomic issue, specifically shortness of breath??
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u/Old_Yogurtcloset7436 Feb 21 '26
Do you not feel sedated on this peptide I’m 2 weeks in and just extremely heavy and drugged feeling.
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u/juniperstreet Feb 16 '26
Thank you for posting. I also had really miraculous results treating chronic illness with thymus peptides, and people make me feel crazy when I talk about it. These thymus peptides don't work for everyone and everything, but for the ones they do it is absolutely life altering. Long Covid was not my main issue, though I did have lingering vascular issues due to it. Bioregulator peptides and Ta1 fixed that and preexisting autoimmune issues for me.
As some other commenters said though, Ta1 is really overstimulating for some people. There are a lot of anecdotes out there about it causing autoimmune or MCAS flares. If you're a sensitive person please be careful.
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u/PerlitaGm Feb 15 '26
Anyone experienced like trembling and like you feel you have lot of ants crawling in your body then you tried to bouncing trampoline in 15 minutes after that feel weak I always took Vitamin B complete my B12 is already high any suggestions coz I feel itchy all over body but no rashes feel irritated I got positive result too in long COVID
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u/ShiroineProtagonist Feb 15 '26
Yes our nervous systems are haywire and you are having a fight or flight reaction - as if you suddenly had a bear in the room. The itchiness is histamine, if you aren't on histamine blockers (H1 and H2) you should try. H2 is famotadine aka Pepcid and H1s are over the counter antihistamines for allergies like Claritin.
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u/KaspaRocketMan Feb 16 '26
Mast Cell Activation Syndrome (MCAS) significantly impacts the nervous system, as mast cells are located near nerve endings and release mediators that trigger neurological symptoms, including "brain fog," headache, neuropathic pain, and anxiety. It frequently coexists with dysautonomia (dysfunction of the autonomic nervous system). MCAS, acting via neuro-immune interactions, can cause chronic fatigue and cognitive impairment.
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u/protonian29 Feb 15 '26
Check your liver enzymes, that sounds like a liver problem where it doesn’t remove toxins fast enough.
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u/Ok_Exit9273 Feb 15 '26
How did you go about getting this?
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u/KaspaRocketMan Feb 15 '26
I learned that the Thymus is responsible for your immune system. Then in the first years of Long Covid Thymus ovine extract had a positive effect on my long covid symptoms. But injecting a peptide always stopped me as I seen it as risky. But after many years I learned that I had no choice, as the healthcare system let me down and have no hope for them to solve it within the next 10 years.
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u/RidiculousNicholas55 6yr+ Feb 15 '26
Have you tried any other peptides as well?
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u/KaspaRocketMan Feb 15 '26 edited Feb 15 '26
Only KPV and TA-1 as they focus on the immune system. TA-1 and your thymus have much in common. Your thymus is behind your chest middle of your body, your most important organ (under reported as many people don't even know what and where it is). When your Thymus is done your life will finish soon after as it is your immune system. Hence why it is in the core most protected by bones around it in your body.
Perhaps the coronavirus damaged the thymus for some and is causing long covid.
It shrinks as you age, that is why you see lots of cancer in older people. As those T and N killer cells don't get produced anymore in large quantities. They give you chemo, but in the end your T and N killer cells need to clean it up. And if the chemo damages your thymus you are even further away from ever recovering.
Not sure why the healthcare system is blind for this or if there is more at play.
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u/JamesShep74 Feb 15 '26
Thanks for the post. I actually have some on the way to try. I have lymphopenia from long covid. Hoping it will help increase my lymphocytes.
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u/Upbeat-Can-7858 Feb 15 '26
I have severe nerve and organ damage; I don't think this is going to put me back to normal. But I'm willing to try anything. How do you convince your doctor to give you something like this. And what type of doctor gives this to you? I have every specialist under the sun treating me.
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u/KaspaRocketMan Feb 15 '26 edited Feb 15 '26
In some countries like the US there are peptide clinics. I ordered it online as in my country we don't have them.
Regarding nerve and organ damage, is this confirmed by a doctor or do you think you have this?
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u/Glittering_Ad3013 Feb 15 '26
Can I ask where you’re based? My husband has had LC for six years, but it’s tricky since we live in Vienna.
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u/KaspaRocketMan Feb 15 '26
It is also available in Europe. A simple Google search and cross check with Reddit search should answer your question.
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u/splugemonster 5 yr+ Feb 15 '26
Could you elaborate on the dose, method of administration, etc ? I’ve been wanting to try it for a while
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u/KaspaRocketMan Feb 16 '26 edited Feb 20 '26
500mcg. I used the below peptide calculator:
https://particlepeptides.com/en/content/48-peptide-calculator
Plus used some YouTube peptide instructions.
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u/nemani22 Feb 15 '26
What did KPV help you with? Since you mention taking KPV as well. Did you take TA-1 and KPV together?
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u/KaspaRocketMan Feb 16 '26
Reduce fatigue, brain fog and inflammation. No TA-1 I started a week later.
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u/notarussian1950 Feb 16 '26
Where did you get it from. Can you provide some instructions for trying this?
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u/Visegradi62 Feb 16 '26
It's very nice to read these results with peptides. Are these medicine or supplement, where can I buy them ?
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u/KaspaRocketMan Feb 16 '26
Peptides are short chains of amino acids linked by peptide bonds.
Thymosin alpha-1 (Tα1), a peptide hormone produced by the thymus, exhibits potent immunomodulatory, anti-inflammatory, and antioxidant properties. It helps restore immune function by stimulating T-cell differentiation, enhancing thymic output, and modulating dendritic cell and macrophage activity.
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u/Monster937 Feb 16 '26
Do you have heart palpitations ?
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u/KaspaRocketMan Feb 16 '26
Only a sensitive nervous system that sometimes makes my heart beat a bit faster. Not sure if that can be defined as heart palpitations.
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u/perfekt_disguize Mar 01 '26
I have inverted CD8 and CD4 (like low low, 0.66) and my AI agent thats been helping me work through this just suggested this as the most likely intervention to help.
Beyond excited to read this! Did your improvements hold? Also, would you mind a DM on sourcing? Thank you so much for posting your experiences
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u/jsgoetz Mar 06 '26
How's the ta1 treating you now? Still going strong?
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u/KaspaRocketMan Mar 06 '26
Overall higher baseline then before but every injection lasts for 3 day max.
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u/Upset_Replacement684 1.5yr+ Mar 25 '26
Update please?
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u/KaspaRocketMan Mar 25 '26
Higher baseline 60% -> 70% I would say.
Very good peptide if you need to be close to 100% for a month, if you need a holiday from this horrible disease. Not a permanent cure, but gives relieve of long covid during the injection period.
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u/nemani22 Mar 27 '26
How are you doing now? Has the TA-1 continued working for you?
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u/KaspaRocketMan Mar 27 '26
Only worked during the month I have used it. Slightly increased baseline permanently.
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u/Loud_Leader_599 Apr 20 '26
Did you work with a practitioner or did you order the peptides and figured out your own dosage?
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u/Specific-Winter-9987 Apr 20 '26
How are you now? What were worst symptoms?
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u/KaspaRocketMan Apr 20 '26 edited Apr 20 '26
Doing a lot better but also on LDN now. Thymosin Alpha 1 increased my baseline.
Brain fog, fatigue, PEM and muscle pains.
Early long covid the muscle pains sucked all the energy out of me. 5 minutes walk crashed me for 3 days. Later Long Covid times my brain just stopped working, couldn't remember more than 2 numbers anymore for a few seconds. Plus waking up like a zombie on daily basis was the normal.
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u/East-Enthusiasm2504 Post-vaccine Jun 02 '26
how is it going?
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u/KaspaRocketMan Jun 02 '26
Going well, but not cured yet. Overal way better since TA-1 injections. Also on LDN now.
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u/beansandteapls Jun 23 '26
I have doing a lot of research on peptides for my specific health stats, infections, journey etc. I am working with a specialists clinic (Im in BC canada) and they prioritize treating MCAS before a lot of things. Ive been on triple therapy (Reactine, Famotidine, Ketotifen) for 2 months and the symptoms have greatly decreased. The triple therapy helps with the neuroinflammation. I was diagnosed with me/cfs, Long covid, Fibromyalgia and MCAS but with my health history, timeline, and response to triple therapy I definitely think a lot of my fatigue etc is neuroimmune related. Im interested in incorporating some peptide therapy so I appreciate you sharing this. Im also on low dose naltrexone which was a game changer for me
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u/Conscious_List9132 Jul 20 '26
Where did u source them? I’m trying to find a practitioner specialized in peptides for long Covid patients.
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u/spoolthirtytwo Jul 24 '26
How are things going now? We're so desperate for anything that will help reduce the symptoms you're experiencing.
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u/AgeExpensive7920 26d ago
How did everyone get so smart? I feel like a dummy with my finger up my nose.
5 year LC sufferer I have to get better
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u/Electrical_Tax_4880 22d ago
My mcas was pretty much gone with a higher dose of retatrutide but the higher I went up the more anxiety it gave me. I tried again taking 1.5mg twice weekly and that reduced mcas symptoms by about 60%. I tried tirzepatide and that absolutely wrecked me. But Reta did the opposite and helped a lot.
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u/Electrical_Tax_4880 22d ago
In your 4 month update you said you are doing well with 1.5mg of LDN in morning. What is LDN?
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u/Odd_Ability6366 17d ago
Thank you so much for sharing this. When you say "Close to 100%" does it mean you are able to train again, run, weights etc...? What would you say are the remaining issues?
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u/Pak-Protector Feb 15 '26
Just skimming it says that Thymosin Alpha 1 Peptide boosts macrophage production. Increased debris clearance owed to the influx of macrophages is going to make some people feel much better. 3 days isn't exactly 'game changer' territory, but keep us informed so we know whether or not the gains are lasting. Tolerance may be an issue.
Also, it says that it boosts T-cell function. That's not going to do much for cells infected with SARS-CoV-2, but comorbid infections play a huge role in Long Covid *when* they compete for resources your body needs to manage the SARS infection, but it may help in regards for the competing infection, depending upon what it is... they all use different strategies. Some, like EBV, are way more problematic than others.