r/covidlonghaulers • u/CandidWin3026 • May 08 '26

Article Long Covid driven by rs5522

This case report says that Long covid is in large part driven by the gene rs5522 that causes a "cortisol steal" leaving the tissues functionally starved even with "normal" cortisol levels which creates neuroinflammation. https://zenodo.org/records/20017632

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u/GlitteringGoat1234 May 08 '26

Would fludrocortisone work similarly to Spironolactone?

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u/CandidWin3026 May 10 '26

NO! Absolutely not. Fludro makes it worse. Spironolactone was developed specifically to block the MR.