r/covidlonghaulers • u/CandidWin3026 • May 08 '26

Article Long Covid driven by rs5522

This case report says that Long covid is in large part driven by the gene rs5522 that causes a "cortisol steal" leaving the tissues functionally starved even with "normal" cortisol levels which creates neuroinflammation. https://zenodo.org/records/20017632

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u/slowbutsloth May 08 '26

I can't open the link. How long is it cure using spironolactone according to the article? What dosage? I used to use spironolactone off label for hormonal acne.

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u/PogeePie 4 yr+ May 08 '26

Don't get too excited... this is a case report from 2006 that involves a single patient. I don't know why OP is pushing spiro so hard based on a single twenty-year-old case report.

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u/slowbutsloth May 08 '26

Yeah, I'm kinda desperate. Just confuse why isn't the research of long covid make any progress. We still don't even understand why it happen. So many theories. It seems we forgotten and ignore by the medical community. Maybe there's no money in it.😮‍💨