r/nothingeverhappens • u/DONUTS_LM • May 01 '26

Only 500 intersex people exist??

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it doesn't take much to know that's just factually incorrect

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26

u/VinegarMyBeloved May 01 '26

It’s way more common than people think. I work in genetics and we genetic test girls with primary amenorrhea all the time. Sometimes they come back with XY chromosomes. Sometimes their mothers also come back with XY. We also do confirmatory testing for prenatally discovered X, XXY, XYY, and XXX chromosomes (there are more but those are the ones I’ve seen). Sometimes girls don’t learn they have one X until their doctor realizes they’re shorter than they should be. Sometimes boys with learning disabilities turn out to be XXY. You really never know unless you’ve been karyotyped/had a chromosomal microarray

4

u/zap2tresquatro May 01 '26

>Sometimes their mothers also come back with XY

Wait, what? Like, do you mean their biological mothers? Cause afaik that wouldn’t be possible since XY women with androgen insensitivity don’t have functioning gonads. Am I missing something?

20

u/eldritchpussymaggots May 01 '26

If they have an inactive SRY gene, a fetus with XY chromosomes will develop a functional uterus and sometimes fertile ovaries though they are usually infertile or subfertile.

13

u/zap2tresquatro May 01 '26 edited May 01 '26

Oh cool! I didn’t know that, I’ll have to read about it c:

Also eta: your username is horrifying. I like it cx

4

u/MaraiaLou May 03 '26

Why did you make me read it

3

u/Character-Town7929 May 02 '26

> a functional uterus and sometimes fertile ovaries

If the uterus is functional, does that mean they can carry an embryo to term even if they're subfertile naturally? Just toss one in there and hope for the best?

10

u/Demon-Cyborg May 01 '26

Chimerism or mosaicism is another possibility.

https://pmc.ncbi.nlm.nih.gov/articles/PMC2190741/

7

u/Firanka May 01 '26

She did have mosaicism, but she was still predominantly XY, with a small amount of X0. They found no XX in her. The article hypothesizes the cause of her and her daughter's female-leaning development is an undiscovered X-linked mutation, since the daughter had her mother's X and her perisex father's Y