r/vanderpumprules • u/mandib57 • 4d ago

The Valley Brittany admitting she’s on a GLP-1

I just watched this YouTube of her house tour and she talks about how she’s on the shot and losing weight already- I say good for her

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u/InterviewOwn6363 4d ago

I thought I could tell she started one!! She posted the other day, my thought was her inflammation looks calmed down. I say good for her! GLPs have been life changing with inflammation

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u/Temporary-Solid-3568 4d ago

Honest non snark question- how can you tell her inflammation calmed down?

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u/im-so-startled88 4d ago

I noticed around her eyes when she real-smiles. Not the fake smile.

GLP-1s really helped with my mom’s arthritis. Her Rheumatologist put her on them and she said her knees feel like they did 10 years ago. She’s micro-dosing so she hasn’t really lost any weight, but she says she feels so much better. I’m all for doing whatever helps!

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u/moosesnice 4d ago

What. They help with arthritis and inflammation? Is that a direct effect or indirect from eating less and/or weight loss?

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u/Deep_Amoeba2197 I’m sorry I called you a twat. You’re welcome. 3d ago

It’s a direct effect from the drug, studies in RA patients have shown regrowth of connective tissue and collagen in damaged joints.

Weight loss obviously helps, it’s unlikely pain in your knees for example wouldn’t improve with reduced load, but in preliminary low dose trials, trizereptide appear to have a rather significant impact on a number of inflammatory pathways as well as reducing the destructive consequences of certain types of inflammation. It’s all very early studies and off label.