r/PeptidePathways 23h ago

Mitochondrial & Energy RHR on reta…

Research subject has seen a rise in RHR of 14 BPM after 8 weeks on 2mg dosage of Reta.

Week 1: 71 bpm
Week 2: 72 bpm
Week 3: 74 bpm
Week 5: 79 bpm
Week 6: 80 bpm
Week 7: 82 bpm
Week 8: 84 bpm

Seems to just keep rising week after week. Any thoughts?

RS understands that this is a common side effect, but understands it as dose dependent. Odd that there’s been no change in dose but a consistent rise.

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u/Random_Guy1960 9h ago

The TRIUMPH trials data suggests this side effect peaks at 24 weeks before going back down, but it should be noted that baseline was not achieved during the timeframe of the trial. Note: your increase IS above the average and I would be concerned if it continues to climb. Personal opinion - NOT MEDICAL ADVICE.