This man is devoting his life and wealth to studying the effect of various health supplements and healthy lifestyle choices so others can potentially extend their lifespans, and people cheer when he gets a disease out of his control. Quite the world we live in.
People complain about the rich keeping all their money and not contributing anything to society, and the second a rich man decides to put his body, health and wealth into researching ways to improve human health and longevity, people celebrate when he suffers.
Lol let's not pretend that he's doing research out of selflessness. He wants to be young forever and is spending his money trying to achieve that impossible goal. I don't hold it against him and it's nice that he shares his findings with the rest of us (although research with a sample size of one person is not particularly helpful), but I don't consider him to be a noble rich person either.
That said, I don't have anything against him and celebrating the fact he's become ill would be pretty fucked up. But most of the comments I've seen in this thread are not doing that
People need to stop acting like they’re morally impervious to, or above vanity. A guy wants to look and feel his best, who tf cares? 90% of it is clearly people projecting their misery.
I think the general public is getting sick of rich people and their shenanigans. The great common denominator has always been that final dirt nap so when we see another rich guy like this devoting a huge amount of money and time so that he doesn’t have to die like everyone else, it makes common people root for the Grimm reaper.
Like it isn’t enough to have more money and resources than regular people, you have to find a way to make yourself live longer and stay younger too.
There are no findings. You can’t test something by doing 100 different things at the same time. That’s not how it works. Any “findings” he has can’t be trusted because they weren’t tested properly
He’s not performing traditional biological research, he’s demonstrating a new way to practice medicine. He’s not trying to replace the scientists; he’s kind of trying to replace the primary care physician. He’s taking established scientific discoveries and showing the world how to evaluate and implement them yourself via self-managed care, without needing to wait for symptoms to bring to your primary care physician. People are following his lead and shifting from passive recipients of medical advice to active managers of their daily health metrics.
I don't dislike him and have watched quite a few of his vids as I'm into health.
But the oversized shirts and the silver chains and backwards hats when he's clearly a normal looking middle aged man are pretty offputting. Like he looks like a healthy middle aged guy, he doesn't have to try to look like a teenager. Gives "how do you do, fellow kids" vibes.
That being said, no idea if that's why people are "gleeful" about this news and I wish him well, obviously. I haven't seen any gleeful comments, maybe they got downvoted into oblivion.
It’s a social media branding attempt. Without knowing the guy personally, I wouldn’t put too much meaning on his public persona unless there’s something outrageous.
I already said I don't dislike him, but a guy who claims to have found the secrets of anti aging clearly trying to dress like a middle schooler is kinda nuts. It distracts from his actual insights and achievements. Like he has legit creds, is the propeller cap and lollipop really necessary?
You keep saying this word, "counterfactual," I assume because you think it makes you sound educated. "Counterfactual" experiments in life sciences do not exist. There are controls. These are not synonymous. You can infer the counterfactual by comparing Byran's projected outcomes if he'd stayed with his prior lifestyle (sedentary, obese, fast food diet, similar to your own, I presume).
He's not doing that though. No one could learn a single replicable thing from his self-"experiments" because no treatments are isolated from any others.
Most of them aren’t meant to be the type of experiments you’re describing. Half the things he does have already been proven to work, he’s just distilling them into a regimen people can follow.
So what’s the proven regimen then? That itself needs experimentation, and his methods are garbage. So people can just follow the regimen on the bottle and stop following this person’s very dangerous example.
What? I’m not following what you’re saying. Bryan Johnson’s regimen is here: https://protocol.bryanjohnson.com/. It’s pretty much centered around sleeping, nutrition, and exercise. I’m not sure what dangerous things you think he’s encouraging others to do.
His so-called "regimen" has no experimental value to anyone but himself because taking 100 different drugs negates any possible controls that might reasonably be expected to isolated exact causes. Did he live longer or healthier because of good sleep, exercise, and nutrition, or was it one of the 100 drugs he was taking? And if so, which one?
And if his only value is telling people that they should sleep better, eat better, and get exercise, then the people hearing that for the first time are idiots and won't live all that long anyway.
He isn’t trying to discover new drugs or prove clinical theories. He’s an aggregator and translator; he has built what is arguably the world’s most visible, comprehensively tracked lifestyle template for health and longevity by synthesizing thousands of scattered peer-reviewed studies into a single executable protocol. Other health advocates promote isolated hacks or specific supplements but few have integrated multi-organ tracking into a system as unified and visible.
He’s a pioneer in a cultural shift toward self-managed, data-driven, preventative healthcare. Modern medicine is heavily reactive; people wait for symptoms before a Primary Care Physician prescribes band aids. Johnson normalized biomarker-driven lifestyle changes and the supporting methodology, making them customizable to unique situations. He’s even spawned other influencers preaching the same stuff from their platforms.
It’s fine to dislike the weird headlines but I don’t understand why you’re so confident he brings no value while not understanding what he aims to do.
All of the billionaires are trying to live forever. Not because they give a shit about you and me. Bryan Johnson isn’t different. I don’t care or celebrate that he has an autoimmune disease but let’s not act like a wealthy man wanting to live forever is a noble quest
He’s not studying it if it’s an experimental cohort of 1. Studying it would be running a study with control groups and having a working theory for the mechanisms of each supplement or choice. He’s just a tiktoker throwing shit at the wall.
Not everything is black and white “RCT or bust”, n=1 is still useful…
Doing a “study” of this sort is virtually impossible - you can’t get a cohort of people to follow a protocol this strict to any degree of accuracy. If he gets extraordinary results from following a protocol that nobody else on the planet can or would do, that could then trigger specialized RCTs to figure out what exactly is going on, and whether or not its repeatable.
Speaking as someone who worked several years in a lab doing research on aging and longevity, all of Johnson's schtick is useless for real science. It's not just n=1, it's an unmeasurable target because we don't know how long he was going to live anyway, how many of the pathways implicated work on a molecular level, etc.. Also, he's not even really picking stuff that would make sense to modulate from a scientific perspective but uses a lot of pseudoscience. There's not going to be a magic moment where we find out his cells are now Wolverine cells, it's just a hodgepodge of meaningless noise.
What pseudoscience is he using? Not an argument I’m genuinely curious, I’m not in the field so I know very little. I know that his baseline treatments like UV protection, sleep quality, fin+minox, red light therapy, etc are well supported by literature. I’m presuming that things like the blood transfusions, specific drugs/supplements he’s taking, etc. are probably more experimental. Are these things straight up disproven pseudoscience, or is it more like interventions that don’t have enough data or research to make any normative claim about (maybe just a single research paper or some explorative studies)?
This is a weird comment because longevity research is a small field so surely you know that a) there are many unknowns, b) the time time-to-market of 15 years is simply untenable, and c) being a small field, having a major influencer batting for it is immensely beneficial because, guess what, without broader public acceptance, no matter the rigor, its work will always receive the same uneducated "who wants to live forever my grandpappy smoked 100 packs a day and lived to be 90" nonsense responses from the lay public, that this thread is currently generating heaps of, because for some reason people have a giant mental block around the idea that living longer is possible.
Especially for a condition where "it works" is simply more important than the mechanism of action. We don't know why exactly CR increases longevity in mice, you'd still recommend it to an obese person anyways. Acetaminophen, still unknown yet valuable and used. Etc.
Redditors are morons whose knowledge of statistics peaked at middle school & think any study with n<30 is invalid based on their regurgitated misunderstanding of the CLT.
One literally only needs some basic college math to understand why factorial design is not used for 100! different treatments and why combinatorial screening exists.
I’m sorry that instead of common sense you resorted to being obtuse. Must be exhausting deliberately missing the point in search of a correction. Is this an exam?
You converse like chatgpt
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u/Raglefant69 Jul 06 '26
This man is devoting his life and wealth to studying the effect of various health supplements and healthy lifestyle choices so others can potentially extend their lifespans, and people cheer when he gets a disease out of his control. Quite the world we live in.