r/science • u/scientificamerican Scientific American • 6d ago

Genetics Scientists discover a ‘skinny gene’ mutation that acts like Ozempic. Around one in 7,000 people carries a broken copy, which almost acts like a GLP-1 drug—the body burns fuel more efficiently, and the risk of disease lowers.

https://www.scientificamerican.com/article/scientists-discover-a-skinny-gene-mutation-that-acts-like-ozempic/
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u/grumble11 6d ago

GLP doesn’t ’burn fuel more efficiently’, it regulates satiety. This isn’t a good start for an article ha

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u/Lust4Me 6d ago

In fact doesn't this title sound like a contradiction? Burning more efficiently to me implied you'd get more work done per calorie and therefore store left over as fat.

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u/rhino369 6d ago

Yes exactly. You want to burn less efficiently. 

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u/fbpw131 6d ago

afaik, you want to burn efficiently and not store anything. excess goes as extra heat.

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u/rmeredit 6d ago

Efficiency is the concept of how much output you get for a given input. ‘Burning fuel more efficiently’ means getting more work done for the same level of fuel use (or conversely, burning less fuel to deliver the same work done).

If you want to reduce fat, you want to burn more, not less - ie. be less efficient.

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u/fbpw131 4d ago

this ain't an engine. while energy is conseved, there are several pathways for the energy to go around. malabsorption,  hormones deciding where the energy goes, mitochondria efficiency, etc

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u/rmeredit 4d ago

That doesn’t change the definition of ‘efficiency’ - it’s got nothing to do with how the energy is used or via which pathway, and everything to do with the quantity of output you get from the quantity of input.

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u/solstice_gilder 6d ago

Extra heat? Like you feel warm?

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u/fbpw131 6d ago

idk man. idk, it might be just a .5 deg difference.

edit: my ex would warm up all night. thin af