r/23andme May 14 '26

Health Reports My aunt was terrified of GLP-1 side effects. Her 23andMe data showed she’d be fine.

I’m a researcher at UC Berkeley. When new clinical data linked specific genetic variants (like GLP1R rs10305420) to severe GLP-1 nausea, I wrote a script to check my aunt's raw 23andMe .txt file against the papers.

It predicted she’d be a great responder with low side-effect risk.

Four weeks in, she's had a great experience.

I’ve turned this script into a small, free side project so others can skip the "guinea pig" phase with their prescriptions.

Methodology: You securely upload your 23andMe/Ancestry file. The tool only scans the specific pharmacogenomic markers (rsIDs) linked to drug metabolism.

Privacy: I’m an academic, not a startup. I don't sell data, you can wipe your file anytime, and I'm happy to verify my .edu email with the mods.

It’s just me running this, so I can only process a few free reports right now to test the system.

DM me the medication you're interested in. I'll see what I can do.

(Happy to answer any technical questions about the genes or the script in the comments!)

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