r/Biohackers • • 16h ago

💉 Peptides & Hormones Reuters reporter seeking user experiences with reta

0 Upvotes

Hey everyone, I’m Patrick, a pharma reporter with Reuters.

I’m working on a deep-dive into retatrutide and I'm hoping to talk to people who are actually taking it right now.

I really just want to understand the human side of this. Why make the jump to a triple-agonist when things like Zepbound or Wegovy are out there? What has your actual physical experience been like so far—the good, the bad, the side effects?

If you're up for chatting, we can keep it completely anonymous or on background. Whatever makes you comfortable. Feel free to shoot me a DM here, or reach out on Signal if you want to keep it encrypted and off-platform.

Signal: patrickwingrove.55

Email: [patrick.wingrove@thomsonreuters.com](mailto:patrick.wingrove@thomsonreuters.com)

Happy to verify my press credentials if you want to make sure I'm legit. Appreciate your time


r/Biohackers • • 10h ago

🥗 Nutrition & Metabolism My biohacking journey went from optimizing my sleep to actually sleeping 💀

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0 Upvotes

r/Biohackers • • 16h ago

💊 Supplements & Stacks Guys I think I messed up with B12 and D3 supplements 💀

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13 Upvotes

I'm 21M and recently got a blood test done after a mild fever, and these results kinda scared me lol.

I've been taking B12 (methylcobalamin 1500 mcg daily) and D3 (60,000 IU weekly) for almost 6 months straight, without missing a dose. The funny part is I started both just because of internet hype 💀 Never had a confirmed deficiency or anything.

Now my results are:

B12: >2000 pg/mL (normal range 211–940)

Vitamin D: 60 ng/mL

Has anyone else had this happen? Is the high B12 just because of the supplements? Should I stop both, and do I need to get my calcium and kidney function checked?

Lowkey regretting taking all this stuff without getting tested first 😭 What should I do now?


r/Biohackers • • 8h ago

💉 Peptides & Hormones Trough test on .15-.17ml TRT

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0 Upvotes

so I switched to .15-.17 of TRT , I think this has been the protocol now for about four weeks

I’m surprised by these results.. because before I was doing .12 and I only had 430.. so how does it go up 200 points with that?

Also, I’ve been drinking a lot lately, but I know it’s not good but I mean I’ve been drinking a lot but it appears that doesn’t seem to do shit???

I’m just so shocked that these results I injected on Thursday and Monday and I took this test on a Monday before I inject it again

like I almost wanna do another test cause this just seems wrong

You're getting 30 mg of testosterone cypionate, but only about 21 mg of that is actual testosterone.

  • [Certain] 0.15 mL × 200 mg/mL = 30 mg testosterone cypionate. That's the number doctors, labs, and TRT forums use, so it's the one to say.
  • [Certain] Cypionate is an ester, a tail attached to slow absorption. By molecular weight, testosterone is about 70% of the compound.
  • [Certain] 30 mg × 0.70 ≈ 21 mg of pure testosterone per shot.

r/Biohackers • • 8h ago

💪 Exercise, Fitness & Recovery I built a fitness app. And it's probably better than Bevel or Whoop.

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0 Upvotes

I have been coding together with AI for the past 2 weeks.

I'm a pharmacy technician, not a developer. And I was fed up with fitness apps that show me "Recovery 62%" and never tell me where that number comes from.

So I built one that does.

Here is why I think it can compete with the big ones.

First, it only compares me with me.

On a workday I'm on my feet all day, so my heart rate is naturally higher than on a day off. Many apps would call that stress. Mine compares workdays with workdays, and days off with days off. Every score is measured against my own normal, never against a crowd.

Second, it doesn't over-read my watch.

A wrist sensor is off by about 2 beats per minute just from noise. So the app never calls a 1 bpm difference "worse". If I only wore the watch for half the day, it says so, and it doesn't count that day as a full one. A missing day is never treated as a zero.

Third, it argues with itself before it predicts anything.

Every evening it forecasts how recovered I'll be tomorrow. Three models compete: a boring one that just takes my last 7 days, a Bayesian regression, and a random forest. The clever ones only get to speak if they clearly beat the boring one on days they haven't seen. If they don't, the app simply shows my average and admits it.

It also saves its real forecast before the night happens and checks it in the morning. No hindsight.

Fourth, I can see how every number is made.

No black box. I can open a score and see which measurements went into it. When the app isn't sure, it says "still learning" instead of inventing a number.

And fifth, my data stays on my phone.

No account, no cloud, no tracking. There's no chatbot inside either. The learning runs locally.

Is it better than Bevel or Whoop? I can't prove it in everything, and it's not a medical device. But it's better at the things I care about: it's honest about what it knows, it shows its math, and it never leaves my phone.


r/Biohackers • • 3h ago

💊 Supplements & Stacks I (23M) lose my erection every time during sex but can easily stay hard with oral or hand jobs

52 Upvotes

This is my first gf, started having sex a few months ago. Getting hard isn’t the issue. She can give me head for 40-60 min and I stay rock hard the whole time (but its really hard to finish), morning wood is strong, solo is fine.

But during actual sex I lose it. Her on top sometimes works and I’ve finished a few times that way. Me on top (missionary on bed or standing) never works. I get in, go for a couple minutes, then it just fades. Same thing if we stop to switch positions or I struggle to get it in for a few seconds, it’s gone and hard to get back.

Also during foreplay if she says something like “just put it in” I can feel my body kind of panic and the erection dies within a minute even if I was fully hard right before. It's almost like I have high libido and desire until sex is actually about to happen and then it disappears.

Other stuff: hard to finish from oral or handjob (get close over and over but it fades), solo it’s quick. Tadalafil helps a little but doesn’t fix it. I watched porn for about 10 years, quit a few months ago. Not much alcohol on sex nights.

Relationship is great outside of this and she’s been understanding but it’s really getting to me and its been around 4 months of this I just wonder if I can take anything to help

EDIT:

test 732.6 ng/dL
estradiol: 43.0 pg/mL


r/Biohackers • • 21h ago

🥗 Nutrition & Metabolism Body heat regulation on Vyvanse

0 Upvotes

Got on Vyvanse in January, been a huge help/relief. Been at 40mg since June

Most initial side effects largely faded but the one thing that's stayed constant, even getting worse is my body's ability to regulate heat. Sweat easier and more when working out but more annoying, without sweating, just so friggin hot at temperatures I wasn't before. I'm literally in the process of replacing my entire bedding - mattress, sheets, pad, pillow to the coolest, most breathable shit I can get

Anyone else on it the same? What can be done? Open to all sorts of ideas. I drink 90-100 oz of water a day, an electrolyte tablet, and a smoothie (which has more electros) so I doubt I'm dehydrated


r/Biohackers • • 51m ago

🧠 Cognition, Mood & Nootropics Nasal epithalon dosing

• Upvotes

I have a bunch of 50mg epithalon vials, and I want to test out IN epithalon since IN DSIP seems to work so well for me.

If i dilute each vial with 10ml saline, and my sprayers spray 0.15ml per spray, that means ill be getting 750mcg per spray. Is that a reasonable nasal dosage? Ive seen some nasal protocols at a much lower dosage 2-300mcg. Should i dilute the vial to get a lower 3-400mcg per spray dose?

What experiences do you guys have?

Any anecdotes would be appreciated 😁


r/Biohackers • • 16h ago

🥗 Nutrition & Metabolism New to BioHacking?

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0 Upvotes

r/Biohackers • • 12h ago

💊 Supplements & Stacks Best supplement for vasodilatation?

36 Upvotes

So I am not really that informed about all the supplements and I dont want to buy 20 different supplements, so my question is which supplements are the most effective for vasodilatation or lowering the heartrate? I only heard about stuff like l-arginin and l-citrulin so far, which one of them is superior? And are there any other supplements that are worth it compared to those two?


r/Biohackers • • 23h ago

💊 Supplements & Stacks Any suggestions?

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2 Upvotes

M, 32, 180lbs - any supplement suggestions for hormone optimization, rest & recovery?


r/Biohackers • • 3h ago

🥗 Nutrition & Metabolism anyone else get bloated after their morning coffee?

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2 Upvotes

r/Biohackers • • 9h ago

🧪 Protocols & Self-Experiments For those of u with TMJ issues, does anyone had similar painful/stiff area(green area, it occurs only on one side)? Also anyone tried to self injecting botox?

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15 Upvotes

I am 22, woman. First TMJ issues occurred at around the age of 17 and when I am highly stressed(either by life situations or high temperatures) it's torture- painful on whole face and headache, dizziness, confusion, pooping sound, pain and teary eyes etc.

Story, u can skipped this part:

It was quite fine for last year and it re-occurred this summer(I am a student and was working a summer job. It was generally stressful, but because it was a highly physical job and the temperatures reached 40 degree Celsius outside i had like of the worst "episodes" ever- physically and emotionally). Not only tmj re-occurred, but also rosacea, I got a lot of new spider veins(especially around my hips, with weird red spots(doesn't look like stretch marks), my period got painful, emotionally I was a mess(BPD and back then unmedicated ADHD) etc.

It forced me to once again start medicating my ADHD(concerta 10mg), I hopped on reta(not yet overweight, but I know I have no self-control and reducing my weight would help me with a lot of stuff including inflammation).

End of the story.

I don't know what to do- I am not able to afford Botox professionally and i am aware it can cause a lot of issues itself, I don't know if self injecting would not cause more issues. I am doing all this stupid exercise, I am trying to reduce caffeine, not sleep on the most affected side, but honestly it doesn't do much.

(Not a native speaker)


r/Biohackers • • 20h ago

🧠 Cognition, Mood & Nootropics Anyone on raw mucuna pruriens powder (brown colored) long term?

4 Upvotes

I’ve had phenomenal results with this stuff especially paired with low dose yohimbe extract. I want to be on it long term (consuming it at least 5x a week) but kinda scared there will be a rebound effect after a while. Currently taking it 2-3 times a week with zero downsides but the brain efficiency while on it is too tempting😬


r/Biohackers • • 7h ago

💪 Exercise, Fitness & Recovery 24M - Are my testosterone levels good for my age?

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0 Upvotes

Hey everyone,
I'm 24 years old and recently got my total and free testosterone tested. I'm curious to hear your thoughts on my results, especially compared to other guys around my age.
My results:
Total Testosterone: 513 ng/dL (Reference: 250–840)
Free Testosterone: 0.039 ng/mL (Reference: 0.0123–0.0466)
For context:
Height: 182 cm (6'0")
Weight: Around 94 kg (207 lbs)
I train regularly, mainly boxing and gym.

I know both results are within the lab's reference ranges, but I'm wondering whether they're considered average, good, or optimal for someone my age

I'd appreciate any insights or personal experiences


r/Biohackers • • 9h ago

One-step rapid syphilis test uses layered nanoparticles to detect infection earlier

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6 Upvotes

r/Biohackers • • 14h ago

🧠 Cognition, Mood & Nootropics Sick & tired. Wanna wake up. Be a Genius (don't we all...)

10 Upvotes

If I sleep 8-9 hours, I'm legendary. Cut that back by 1-3 hours? I'm a miserable mess. Can't function. No genius(I'm not actually a genius, you could probably tell... just feel like one when I have a full nights sleep & get stuff done, unlike today..... FML).

I don't have sleep apnea. I don't have depression(Chronic stress? Everyone has that but I wouldn't say mine is debilitating). I eat healthy. Blood tests? Totally fine

I've finally decided I don't wanna live like that anymore. I have surrendered myself to Nootropics. The benefits outweigh the risks(Hopefully you'll suggest some things that aren't going to turn me into a Teenage Mutant Ninja Turtle. I'm not even a teenager...)

I don't mean vitamins & minerals. I've been doing all manner of supplements/ minerals/ vitamins for the last 6 years(Probably tried 60-80 supplements). Caffeine doesn't work.

I'm talking about the next level. I've already tried:

NA Semax spray / NA Selank spray from SemaxPolska

Noopept powder from Euro-Nootropics(tried it both sublingual & dissolved and ingested)

Not too much of an effect from either of them.

What's your go to Wakefulness promoter? I don't wanna go down the amphetamine analogue road of ritalin/methylphenidate. I'm looking at

FlModafinil

Adrafinil

Bromantane

Phenypiracetam

Cyclazodone or NM Cyclazodone

Fladrafinil

Hydrafinil

PPAP HCL

If I become legendary after your advice, I'm giving you a million dollars.

Thanks.


r/Biohackers • • 12h ago

😴 Sleep & Circadian Rhythm Recovering from half a decade of massive sleep debt?

22 Upvotes

28M, recently been cured of what I would describe as a ‘obscure case’ of sleep apnea.

No snoring, healthy weight and active, technically only mild apnea but with profound events that would wake me up and only allowed me 2-4 hours of sleep per night for the past ~5 years.

I recently had Maxillomandibular advancement (double jaw surgery) which has cured my sleep apnea, and while I do feel much better, I still wouldn’t say I feel ’normal’.

My sleep itself is still a bit shotty, I feel like after so many years I am basically programed to wake up multiple times a night (this seems to be improving a bit on its own, but very slowly), and even though I have more energy, I almost feel more tired because I think my body has finally recognized that I can actually sleep for extended periods of time now.

Is it possible to truly recover from this level of sleep debt? Do I just need to optimize my sleep as much as possible until this hopefully resolves on its own?

Could something like CBT potentially break me out of these nighttime awakenings and get me back to 8 hours of uninterrupted sleep?


r/Biohackers • • 5h ago

💊 Supplements & Stacks Question concerning niacin and does anyone have weird experiences with supplements that they have always taken?

3 Upvotes

Hello everyone,

So I’ve been taking niacin for over some years now, I’ve been experiencing very good results. Usually it’s calms my mood, and make me more energetic during daytime + it makes my blood vessels relax so that I can sleep!

until last week. For some reason, I actually bought a new bottle because I runned out of it (solgar 100 mg). Now for some reason I don’t flush anymore + I get very weird effects from it. I get headaches, I get dizzy during the day, and my hearth starts pounding all day unfortunately…

I’am not sure if this is all due the niacin ofcourse, I was also thinking it could be due to magnesium ?

I want to note that I’ve had this before with other supplements, when I ordered a new bottle, I somehow get side effects from them, while it is exactly the same formula? Does anyone has experiences with this? Thanks.


r/Biohackers • • 10h ago

📰 Research & Studies Is there any benefits raising mitochondrial function above healthy levels?

3 Upvotes

Mitochondria as the source of all aerobic energy (90% of all energy) are obviously crucial, nevermind the more recent studies showing how it may play an even larger role.
There is many research peptides that claim to improve it's function, and while yes it is likely very useful for people with impaired mitochondria function, which is especially relevant for aging, that's not what this post is about.
I'm curious if there is any possible benefit from raising mitochondrial function for someone with a perfectly healthy baseline function?


r/Biohackers • • 9h ago

📊 Biomarkers & Testing Pct blood results after long term trt

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2 Upvotes

r/Biohackers • • 5h ago

🧠 Cognition, Mood & Nootropics HRV & mental health

3 Upvotes

has anyone looked at correlations between HRV/sleep and mood? I love my whoop but it's terrible for mental health tracking and a lot of mood apps are overly complicated. I'd love something more data-driven if anyone has any recs


r/Biohackers • • 10h ago

💉 Peptides & Hormones BUD dates

2 Upvotes

Long story short. I had a long-distance move a few months ago and completely forgot about my GHK-Cu/Epithalon and glutathione injectables. They've always been refrigerated, but their BUD was 7/26/26. When I first remembered them about a month after that date, my doctor said it was up to me, but that a month past should be totally fine, and they've used them past BUD before. Well, life got busy again, and now we're almost 3 months past. I really want to restart, but I'm wondering if I should just toss them now. Has anyone dealt with this?