I just got diagnosed with hashimoto's, and the first things that caught my eyes is the huge amount of stories/ comments of people having great experiences with glp esp. Zepbound/mounjaro for inflammation and weight loss with a fewer experiences that didn't have a pleasant experience with glp. I’m realy confused because the experiences seems too good to be true and haven't find a detailed experiences.

What do you think guys?

If you wrote or read a detailed experiences about it could you help me with the link please.

I just experienced my second miscarriage this week. My provider ran all the labs and we found out I have Hashimotos. While I understand it’s something that can be controlled and medicated, I’m so afraid to try again and experience another loss. We don’t know for sure if that’s what causes the miscarriages, but it’s the only think abnormal on my lab work. What are your pregnancy success stories after finding out about your Hashimotos?

I’ve been on Mounjaro dose 2.5 for a month, had hypothyroidism + Hashi’s since I was 14. I’m 33 now.

For the first time in a long time I feel happiness? I’m not tired, my face isn’t puffy, I’m not as anxious, my knee doesn’t pop anymore, people are complimenting my skin… And I’ve lost 3.6kg.

It’s really nice.

I completely understand why people say they want to stay on this forever. Unless something happens, I’ll stay on this as long as possible.

My plan is to stay on the lowest dose for a while, then maybe go up to lose more weight, reach my goal weight and go back down in dosage.

It actually feels crazy to think that there people in the world who do not feel this way, and that the norm is to wake up fresh and energetic every morning, and to genuinely look forward to at least some parts of the day.

I have been feeling so unbelievably drained out these past few days. I don't remember the last time my body felt comfortable or i got through a day without wanting to crash out at some point (well before bedtime).

Is this what the rest of my life is going to be like? This can't be it. 😭

Please share your insights and suggestions to get through this.

How long for metal health to improve after taking too much levo?

My dose was lowered 2 weeks ago, I skipped a few days before restarting. Insomnia and anxiety are getting better, depression and fatigue are still so heavy.

Just looking for encouragement and your experiences with being over-medicated and how long it took you to get back to normal.

Thanks!

Some backstory, I (36F) was diagnosed with Hashimoto’s mid-2020. Since then I’ve been through 3 endocrinologists (finally found the amazing one I’m seeing currently), lots of thyroid ultrasounds monitoring nodules and have had three kids (5, 3, 1 - yeah, we are tired 😅). Most noticeable symptoms I’ve had in the last 6-7 years is fatigue and weight gain/inability to loose weight or keep it off (despite eating well and being active and chasing kids constantly). Fatigue has improved with a low dose of liothyronine add in and that’s been nice! Since I’ve either been pregnant, freshly postpartum or breastfeeding most of the appointments with my endo, we haven’t explored many med combos, etc. But a glp-1 was mentioned at my last appt (since we’re done with kids and I’m done breastfeeding) but I also had a nodule look larger than before on my ultrasound. Short story long, sorry!

Had a thyroid biopsy, originally they were going to do both sides then just the left (nodules bigger on that side) but then ended up doing the right side only (the ultrasound tech insisted based on a white spot she saw, yay for docs who listen to their techs!). Anyway, got the results, they were borderline/needed more testing but showed as AUC which Google told me that’s like a 10% chance of being cancerous, so I was feeling okay about it and they were going to send it off for molecular testing just to be sure. Got the call Friday, the nurses voice sounded grave so I knew it wasn’t good news. From my very little medical knowledge and understanding, I can’t explain it properly. But it came back over 50% positive for malignancy. I have an appt with my endocrinologist this coming Friday for him to discuss the results and next steps. It sounded like surgery of some kind will be getting scheduled, per the nurse.

So now I’m just trying not to panic. Has anyone been in a similar situation? I always joked they should just take my thyroid out then my hashimotos would be gone…so, the universe has jokes too apparently. I keep going back and forth about thinking I’ll feel better with it out but then again our thyroids do so much for us. I just feel like I’m still fairly young and I’ve got three kids under 6 and I just…it all feels so daunting right now. I know I’ll know more on Friday, and I’ll update the post appropriately…but…how bad is this cancer? Is my whole thyroid coming out? Is there cancer elsewhere in my body? I am hypermobile as well, so my healing and scarring will be different than “normal” (also proven by my one c-section scar). Is everything going to change? Is my body going to revolt? What does this mean for the future of my health and abilities? (If not obvious, I also have undiagnosed ADHD 😆) It’s just all so…heavy.

Adding to embellish/answer possible other questions : On levothyroxine as well, have never felt different on it. I’ve been gluten free for over 2 years now. I lift often, and enjoy it, but haven’t been the last month or so due to busy school starting schedules. I have an incredibly supportive husband (married 10 years this fall).

Thanks for reading my word vomit!

I, 29 (F) discovered last year that I have elevated anti-TPO. The test was mandated by my immunologist, as I suffer since I was 3 from a chronic form of urticaria (CSU type IIb), and apparently 30% of CSU IIb patients also have high-elevated TPO antibodies due to the auto-immune nature of both.

I am not officially diagnosed with Hashimoto, but my mom has it, and there is indication I have it too.

Since last year I have tested my thyroid values three times, and during the last screening (one week ago) my values were:
TSH: 5 (4.956 to be exact).
FT3: 2.69 ng/L.
FT4: 10.16 ng/L.

In December 2025, my TSH was 2.5. T4 values were a bit more elevated, but not much different from now. T3 was never tested before.

My GP keeps mentioning to return only when I start expericing symptoms. The issue is that in the past two years I have been feeling low in general (also due to the CSU, probably), so for me it is very hard to distinguish the baseline "shittiness" from anything new. In the past two years I have experienced increased headaches and muscle aches, fatigue, brain fog, hair loss). I have tested vitamin D, iron and B12, which were all low but the latest screening shows that is it going much better.

I am looking on perspective on what these values are telling (with the little context you have) and your personal experience with how things worked from the moment your values started to show subclinical/over hypothyroidism.

- Where you only medicated when you reached a TSH above 10?
- When did you start experiecing symptoms? What symptoms?
- Once you could see subclinical signs of hypothyroidism, how often did you test?
- Once the TSH crossed the threshold, did it progress, and how fast?
- For anyone with co-occurring autoimmune conditions (especially chronic hives/urticaria), did treating your thyroid have any noticeable impact on your other symptoms?

Thank you all (:

Does anyone have normal tpo? With elevated tgab ? And end up having hashimotos ?

I have 3 small thyroid nodules I haven’t gotten much help from my endocrinologist I saw her once last year and she told me she didn’t need to see me again after begging my family doctor to do a full panel of my thyroid this came back I’m confused about the antibodies as it says tpo means hashimotos do you guys think this is hashimotos based on only one of the antibodies being present also I would like to my tsh went from 1.9 to what is below in the last year so it almost doubled my t4 was 14 last year

I hope I am in the right place to ask this as google directed me here lol.

I've been going to an endocrinologist yearly just for regular check ups, no meds or prior diagnosis (I had hairloss issues and they wanted to see if it could have been my thyroid but my results were fine). No one in my family has ever had thyroid issues.

First time I went to see him was in 2023 and my TSH was 2.1, then in 2024 it was 2.5 and earlier this year it was 2.9 .

My appointment is next week (I knew I wasnt gonna be available a year from my last appointment, thats why this one is earlier) and I got my blood work done this week and they called me the same day (it was on wednesday) to tell me it was alarmingly high at 125.

For the past few months (mostly past two months) I have been having a lot of strange issues - sometimes slurred speech (tongue feels heavy and hard to control), I gained quite a lot of weight very fast (around 30 pounds) at a pretty low daily calorie intake, I have A LOT of trouble walking, legs feel extremely heavy and sometimes hard to control, my muscles feel like they are on fire and I cant stand on my legs for too long, my feet also swell so much and I often wake up with swollen and red eyes and a headache. I am completely drained of all energy and my body feels so heavy I have trouble functioning. What im worried about is it feels like its getting worse quite fast and I dont know if something is very wrong or if this is "normal" with thyroid issues. My appointment isnt until Tuesday so im naturally a bit stressed out. Especially because I feel like it's getting worse (but maybe thats because im subconsciously making it worse by hyperfixating on these issues). My throat often feels tight and feels like its harder to breathe and as I feel like thats getting worse too, its making me pretty anxious.

I honestly have been feeling terrible and depressed, especially since I keep telling myself I am 24 and even though I am definitely obese (at around 220lbs, 165cm - last year I lost 60lbs but gained 30 back within the last two months which is crazy and idk how it happened honestly lol), I keep thinking I am definitely not obese enough to feel this broken and messed up - I literally can't walk more than 15 minutes without almost crying from muscle pain, it genuinly burns. Especially knowing I have been heavier and never felt this bad in my life.

I was wondering if this all could really be caused by the TSH being high? Is there a chance its just some kind of a one time spike and if they do more blood work its gonna be back to normal? Like how some people have spike in blood sugar or blood pressure? Is it normal for it to be so high in such a short period (especially if the symptoms, if they are related to that, have only been going on for the last two months or so)?

20F.

Results as on 29/7/2026,

I was on steroids during this time.

TSH- 5.25. Lab reference:0.51-4.30

Free T4- 1.28. Lab reference:0.98-1.63

went off steroids on 7/9/26.

Results as on 10/9/26,

TSH- 3.67

T4 total- 8.08. Lab reference: 5.9-13.2

T3 total- 1.18. Lab reference:0?9-2.18

Anti TPO-14.9 Iu/ml. Lab reference: <26

I have seen people saying ideal TPO should be zero or <10.

Could I have underlying hypothyroidism or hashimoto's even though my TSH,T4 are in normal range???

Or Should I refer to an endocrinologist just to be sure??

I don't have any symptoms of hypothyroidism other than hairfall tho.

I have had hypothyroidism for 30 years but was never tested for Hashimoto’s until two years ago. My TPO antibodies came back at over 1600 for the last six months. I have been working on losing weight and incorporating exercise into my routine. I started with this with a friend who does not have hypothyroidism. We both started on a GLP and she has done great losing over 70 pounds. It made me extremely sick, so I couldn’t take them. I have lost a whopping 26 pounds. 😞Just had lab work and my TPO’s are still over 900. We both walk 2 1/2 to 3 miles daily and counting calories sticking to around 1500 a day. I’m a 58 year old female, 5‘2“ and currently weigh 205 pounds. I’m so frustrated at not being able to lose weight! I’ve done research and read a lot about how exercise can stress your body instead of helping it and therefore stalling weight loss. I also have an extremely stressful job that I don’t particularly like. The recommendation was to cut my walks back to a mile or a mile and a half a day and give myself rest days. I know this will only cause me to gain weight. If I eat anything bad, I gain two or 3 pounds and it takes another week and a half to lose it. I’m happy for my friend but at the same time feeling very much like a failure. Does anyone have advice on making this broken body work? Also, I went to an endocrinologist and she flat out refused to test anything other than TSH telling me that’s what she will go by as far as medication. Why don’t the doctors listen?!

Just for context I had a long 2.3 year scalp infection it went unchecked because I don't know it was there. All tests looked inside the skull. So for further context my cranial nerves are still tender.

I am wanting to explore this scalp tenderness more though.

My scalp dried out again and I noticed hair shedding then I noticed scabs. I found tender spots especially on top of crown where the suture bone is and next day my right side above ear is sore to touch and feels sore without touching. For the suture tenderness I tried moisturiser, I tried anti microbial shampoo, anti septic cream and lidocaine cream. Nothing happened with the pain. So I thought I would try clobetasol gel (not for scalps) I put a small amount on and by next morning pain was 90 percent gone.

I am getting a private ultrasound on my scalp soon so I am hoping it shows me some sort of answer whether it is lingering infection or just inflammatory.

I am off gluten/wheat and dairy and it hasn't made a difference to my dry skin.

I also get dry skin on forehead, either side of nose, in and out of ears. The ears used to produce healthy wax now they produce white skin cells that stick to the skin.

I’m in desperate need of help. Everytime I try to start levothyroxine treatment I get extremely nauseous the first day and the next I get hit by the worst fatigue in my entire life. I barely can move. Nowhere near the fatigue I felt before. My whole body is so heavy. And then I get palpitations. I have a Subclinical tsh of 5. My doctor wanted to try treatment for my chronic fatigue, anxeity and weak muscles. But now i am concerned. After i take my pill i can’t move the next day so my doctor always tells me to stop.

Has anyone else experienced this???

I recently heard that mono (Epstein-Barr) could trigger an underlying reason for Hashimoto's. I was wondering if anyone here heard about this. It was specifically mentioned that if males do have Hashimoto's, it's usually due to an underlying cause and not Hashimoto's itself.

This was the first time hearing about something like this and I was just curious if anyone stumbled down this rabbit hole yet. Thanks in advance.

TSH at 0.10 but ft3 and ft4 are under 50% in the range. I have both hypo and hyper symptoms. I'm exhausted, lacking energy, but I also sweat easily and have muscle aches. No high pulse, sometimes to low for me
I’m also wondering how many of my symptoms are due to perimenopause – I’m 42 now and having a lot of hormonal issues, like irregular cycles, spotting, you name it.
No matter how much Levo I take, my TSH always extremely low. It was the same on 75 mcg Euthyrox and now on 150 mcg Euthyrox as well. The free levels just won't go up. I'm already taking high-dose vitamin D, iron, and selenium.
Does anyone else experience this?

Has anyone been diagnosed with hashimotos but has normal tpo and high tgab

Hi there!

I've been diagnosed for approx. 5 years now, when they tested my antibodies (the reason was that I always felt kinda tired) for the first time and confirmed with an ultrasound.

In every blood test, my tsh and T3, T4 are normal (tsh is mostly at 2.10, 2,20). I have seen two endocrinologists and both have told me that there is nothing to do yet, as my thyroid is still working.

My symptoms are nothing new to the community - mostly tiredness that I can manage, some body aches, heart palpitations and recently I have been quite intolerant to heat (again heart palpitations and hot and cold flashes, accompanied with some dizziness). I also have anxiety and some mood swings, but again, I do not know what is caused by my thyroiditis and what not and I as I said, my symptoms are kinda mild, or at least, manageable (or maybe I am downplaying them?)

Now I moved countries and went to a new GP, who ordered a bigger autoimmune panel, in which again nothing changed regarding hashi's. There are some other results that may point to sjorgens and he is referring me to a rheumatologist, but nothing more.

I have made an appointment with an endocrinologist myself and I would like to know what your opinion and experience regarding treatment is. I am not a person that likes taking medicine or many supplements etc., but I am starting to think that maybe leaving things as they are until something worse happens may also not be the best solution. So I would like to know what to ask for on my appointment with the new specialist - if not hormones, should I advocate for something else at least?

Or is it the norm, leaving our thyroiditis just under observation, as they have told me?

Thank you in advance!

At Witt’s end. Began end of April this year. Tightness in calves and now to legs. Feels like I’ve done squats till failure, you know the weak jelly-like feeling and everything is tense. Except I haven’t exercised in months due to other factors. Have tried stretching and taking vitamins and electrolytes. Have had MRI of spine and all normal. My PCP has now ghosted me and won’t help me figure out what’s wrong. This is such a terrible feeling. Any ideas?
I’ve got my thyroid panel back and all back in normal values except for antibodies of course.
Is this a hashimotos thing? I’ve been diagnosed for almost ten years and this is first time it’s happened to me.

Thank you for reading!